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McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Bohm M, et al. 2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure. <i>Eur Heart J<\/i> 2021; 42: 3599\u20133726.","DOI":"10.1093\/eurheartj\/ehab368"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Vos T, Allen C, Arora M. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990\u20132015: A systematic analysis for the global burden of disease study 2015. <i>Lancet<\/i> 2016; 388: 1545\u20131602.","DOI":"10.1016\/S0140-6736(16)31678-6"},{"key":"3","unstructured":"3. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Heart disease and stroke statistics \u2013 2015 update: A report from the American Heart Association. <i>Circulation<\/i> 2015; 131: e29\u2013e322."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Okura Y, Ramadan MM, Ohno Y, Mitsuma W, Tanaka K, Ito M, et al. Impending epidemic: Future projection of heart failure in Japan to the year 2055. <i>Circ J<\/i> 2008; 72: 489\u2013491.","DOI":"10.1253\/circj.72.489"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Ziaeian B, Fonarow GC. Epidemiology and aetiology of heart failure. <i>Nat Rev Cardiol<\/i> 2016; 13: 368\u2013378.","DOI":"10.1038\/nrcardio.2016.25"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Long L, Mordi IR, Bridges C, Sagar VA, Davies EJ, Coats AJ, et al. Exercise-based cardiac rehabilitation for adults with heart failure. <i>Cochrane Database Syst Rev<\/i> 2019; 1: CD003331.","DOI":"10.1002\/14651858.CD003331.pub5"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Belardinelli R, Georgiou D, Cianci G, Purcaro A. 10-Year exercise training in chronic heart failure: A randomized controlled trial. <i>J Am Coll Cardiol<\/i> 2012; 60: 1521\u20131528.","DOI":"10.1016\/j.jacc.2012.06.036"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. 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Effects of aerobic and inspiratory training on skeletal muscle microRNA-1 and downstream-associated pathways in patients with heart failure. <i>J Cachexia Sarcopenia Muscle<\/i> 2020; 11: 89\u2013102.","DOI":"10.1002\/jcsm.12495"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Ayad SW, Hassanein M, El Dabe FWY, El Amrawy A. Impact of cardiac rehabilitation on patients with heart failure with preserved ejection fraction. <i>J Am Coll Cardiol<\/i> 2021; 77: 574.","DOI":"10.1016\/S0735-1097(21)01933-1"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Baldassarri F, Schwedhelm E, Atzler D, B\u00f6ger RH, Cordts K, Haller B, et al. Relationship between exercise intervention and NO pathway in patients with heart failure with preserved ejection fraction. <i>Biomarkers<\/i> 2018; 23: 540\u2013550.","DOI":"10.1080\/1354750X.2018.1460762"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Bernocchi P, Vitacca M, La Rovere MT, Volterrani M, Galli T, Baratti D, et al. Home-based telerehabilitation in older patients with chronic obstructive pulmonary disease and heart failure: A randomized controlled trial. <i>Age Ageing<\/i> 2018; 47: 82\u201388.","DOI":"10.1093\/ageing\/afx146"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Chen Y, Funk M, Wen J, Tang X, He G, Liu H. Effectiveness of a multidisciplinary disease management program on outcomes in patients with heart failure in China: A randomized controlled single center study. <i>Heart Lung<\/i> 2018; 47: 24\u201331.","DOI":"10.1016\/j.hrtlng.2017.10.002"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Chen YW, Wang CY, Lai YH, Liao YC, Wen YK, Chang ST, et al. Home-based cardiac rehabilitation improves quality of life, aerobic capacity, and readmission rates in patients with chronic heart failure. <i>Medicine (Baltimore)<\/i> 2018; 97: e9629.","DOI":"10.1097\/MD.0000000000009629"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Chou CH, Fu TC, Tsai HH, Hsu CC, Wang CH, Wang JS. High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. <i>Int J Cardiol<\/i> 2019; 274: 214\u2013220.","DOI":"10.1016\/j.ijcard.2018.07.104"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Dalal HM, Taylor RS, Jolly K, Davis RC, Doherty P, Miles J, et al. The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: The REACH-HF multicentre randomized controlled trial. <i>Eur J Prev Cardiol<\/i> 2019; 26: 262\u2013272.","DOI":"10.1177\/2047487318806358"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Ellis RE, Dodd KJ, Holland AE, Lim K, Tacey M, Shields N. Effect of eccentric exercise on quality of life and function in people with chronic heart failure: A pilot randomized controlled trial. <i>Disabil Rehabil<\/i> 2022; 44: 2705\u20132714.","DOI":"10.1080\/09638288.2020.1836679"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Fabri T, Catai AM, Ribeiro FHO, Junior JAA, Milan-Mattos J, Rossi DAA, et al. Impact of a supervised twelve-week combined physical training program in heart failure patients: A randomized trial. <i>Cardiol Res Pract<\/i> 2019; 2019: 1718281.","DOI":"10.1155\/2019\/1718281"},{"key":"21","unstructured":"21. Giovannini S, Coraci D, Di Caro F, Castelli L, Loreti C, Chicco A, et al. Prehabilitation and heart failure: Perspective in primary outcomes, a randomized controlled trial. <i>Eur Rev Med Pharmacol Sci<\/i> 2021; 25: 6684\u20136690."},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Groennebaek T, Sieljacks P, Nielsen R, Pryds K, Jespersen NR, Wang J, et al. Effect of blood flow restricted resistance exercise and remote ischemic conditioning on functional capacity and myocellular adaptations in patients with heart failure. <i>Circ Heart Fail<\/i> 2019; 12: e006427.","DOI":"10.1161\/CIRCHEARTFAILURE.119.006427"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Guimar\u00e3es GV, Ribeiro F, Castro RE, Roque JM, Machado ADT, Antunes-Correa LM, et al. Effects of the exercise training on skeletal muscle oxygen consumption in heart failure patients with reduced ejection fraction. <i>Int J Cardiol<\/i> 2021; 343: 73\u201379.","DOI":"10.1016\/j.ijcard.2021.08.050"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Kitzman DW, Whellan DJ, Duncan P, Pastva AM, Mentz RJ, Reeves GR, et al. Physical rehabilitation for older patients hospitalized for heart failure. <i>N Engl J Med<\/i> 2021; 385: 203\u2013216.","DOI":"10.1056\/NEJMoa2026141"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Koppen E, Omland T, Larsen AI, Karlsen T, Linke A, Prescott E, et al. Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction. <i>ESC Heart Fail<\/i> 2021; 8: 2183\u20132192.","DOI":"10.1002\/ehf2.13310"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Lan NSR, Lam K, Naylor LH, Green DJ, Minaee NS, Dias P, et al. The impact of distinct exercise training modalities on echocardiographic measurements in patients with heart failure with reduced ejection fraction. <i>J Am Soc Echocardiogr<\/i> 2020; 33: 148\u2013156.","DOI":"10.1016\/j.echo.2019.09.012"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Lang CC, Smith K, Wingham J, Eyre V, Greaves CJ, Warren FC, et al. A randomized controlled trial of a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction and their caregivers: The REACH-HFpEF pilot study. <i>BMJ Open<\/i> 2018; 8: e019649.","DOI":"10.1136\/bmjopen-2017-019649"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Liu MH, Wang CH, Tung TH, Kuo LT, Chiou AF. Effects of a multidisciplinary disease management programme with or without exercise training for heart failure patients: Secondary analysis of a randomized controlled trial. <i>Int J Nurs Stud<\/i> 2018; 87: 94\u2013102.","DOI":"10.1016\/j.ijnurstu.2018.06.010"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Lugo LH, Navas CM, Plata JA, Ortiz SD, Caraballo D, Henao AC, et al. Ensayo cl\u00ednico aleatorizado para evaluar el efecto de un programa de rehabilitaci\u00f3n cardiaca supervisado con ejercicio en el consumo de ox\u00edgeno, la funci\u00f3n y calidad de vida de pacientes con falla cardiaca cr\u00f3nica. <i>Rev Colomb Cardiol<\/i> 2018; 25: 106\u2013115.","DOI":"10.1016\/j.rccar.2017.05.018"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Maru S, Mudge AM, Suna JM, Scuffham PA; EJECTION-HF Trial Investigators. One-year cost-effectiveness of supervised center-based exercise training in addition to a post-discharge disease management program for patients recently hospitalized with acute heart failure: The EJECTION-HF study. <i>Heart Lung<\/i> 2019; 48: 414\u2013420.","DOI":"10.1016\/j.hrtlng.2019.03.003"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Mueller S, Winzer EB, Duvinage A, Gevaert AB, Edelmann F, Haller B, et al. Effect of high-intensity interval training, moderate continuous training, or guideline-based physical activity advice on peak oxygen consumption in patients with heart failure with preserved ejection fraction: A randomized clinical trial. <i>JAMA<\/i> 2021; 325: 542\u2013551.","DOI":"10.1001\/jama.2020.26812"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Peng X, Su Y, Hu Z, Sun X, Li X, Dolansky MA, et al. Home-based telehealth exercise training program in Chinese patients with heart failure: A randomized controlled trial. <i>Medicine (Baltimore)<\/i> 2018; 97: e12069.","DOI":"10.1097\/MD.0000000000012069"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Piotrowicz E, Pencina MJ, Opolski G, Zareba W, Banach M, Kowalik I, et al. Effects of a 9-week hybrid comprehensive telerehabilitation program on long-term outcomes in patients with heart failure: The telerehabilitation in heart failure patients (TELEREH-HF) randomized clinical trial. <i>JAMA Cardiol<\/i> 2020; 5: 300\u2013308.","DOI":"10.1001\/jamacardio.2019.5006"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Pourhabib A, Fotokian Z, Nasiri M, Abrotan S. Effects of a group-based aerobic and resistance exercise program on physiological-psychological adaptation in elderly with heart failure. <i>J Clin Gerontol Geriatr<\/i> 2018; 9: 59\u201366.","DOI":"10.24816\/jcgg.2018.v9i2.05"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Pozehl B, Duncan K, Hertzog M, Norman JF. Heart failure exercise and training camp: Effects of a multicomponent exercise training intervention in patients with heart failure. <i>Heart Lung<\/i> 2010; 39(Suppl): S1\u2013S13.","DOI":"10.1016\/j.hrtlng.2010.04.008"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Redwine LS, Wilson K, Pung MA, Chinh K, Rutledge T, Mills PJ, et al. A randomized study examining the effects of mild-to-moderate group exercises on cardiovascular, physical, and psychological well-being in patients with heart failure. <i>J Cardiopulm Rehabil Prev<\/i> 2019; 39: 403\u2013408.","DOI":"10.1097\/HCR.0000000000000430"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Sadek Z, Ahmaidi S, Youness M, Awada C, Joumaa WH, Ramadan W. 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Turri-Silva N, Vale-Lira A, Verboven K, Quaglioti Durigan JL, Hansen D, Cipriano G Jr. High-intensity interval training versus progressive high-intensity circuit resistance training on endothelial function and cardiorespiratory fitness in heart failure: A preliminary randomized controlled trial. <i>PLoS One<\/i> 2021; 16: e0257607.","DOI":"10.1371\/journal.pone.0257607"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43. Valborgland T, Isaksen K, Munk PS, Grabowski ZP, Larsen AI. Impact of an exercise training program on cardiac neuronal function in heart failure patients on optimal medical therapy: A randomized iodine-123 metaiodobenzylguanidine scintigraphy study. <i>J Nucl Cardiol<\/i> 2018; 25: 1164\u20131171.","DOI":"10.1007\/s12350-016-0724-8"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44. Taylor SA, Mallett S, Miles A, Morris S, Quinn L, Clarke CS, et al. Whole-body MRI compared with standard pathways for staging metastatic disease in lung and colorectal cancer: The streamline diagnostic accuracy studies. <i>Health Technol Assess<\/i> 2019; 23: 1\u2013270.","DOI":"10.3310\/hta23660"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45. O\u2019Connor CM, Whellan DJ, Lee KL, Keteyian SJ, Cooper LS, Ellis SJ, et al. Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. <i>JAMA<\/i> 2009; 301: 1439\u20131450.","DOI":"10.1001\/jama.2009.454"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46. Taylor RS, Walker S, Smart NA, Piepoli MF, Warren FC, Ciani O, et al. Impact of exercise rehabilitation on exercise capacity and quality-of-life in heart failure: Individual participant meta-analysis. <i>J Am Coll Cardiol<\/i> 2019; 73: 1430\u20131443.","DOI":"10.1016\/j.jacc.2018.12.072"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47. Cahalin LP, Chase P, Arena R, Myers J, Bensimhon D, Peberdy MA, et al. A meta-analysis of the prognostic significance of cardiopulmonary exercise testing in patients with heart failure. <i>Heart Fail Rev<\/i> 2013; 18: 79\u201394.","DOI":"10.1007\/s10741-012-9332-0"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48. Ferreira JP, Metra M, Anker SD, Dickstein K, Lang CC, Ng L, et al. Clinical correlates and outcome associated with changes in 6-minute walking distance in patients with heart failure: Findings from the BioStat-CHF study. <i>Eur J Heart Fail<\/i> 2019; 21: 218\u2013226.","DOI":"10.1002\/ejhf.1380"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49. Marume K, Takashio S, Nakanishi M, Kumasaka L, Fukui S, Nakao K, et al. Efficacy of cardiac rehabilitation in heart failure patients with low body mass index. <i>Circ J<\/i> 2019; 83: 334\u2013341.","DOI":"10.1253\/circj.CJ-18-0852"},{"key":"50","doi-asserted-by":"crossref","unstructured":"50. 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