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Vericiguat in patients with heart failure and reduced ejection fraction. <i>N Engl J Med<\/i> 2020; 382: 1883\u20131893.","DOI":"10.1056\/NEJMoa1915928"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Fukui A, Takahashi N, Nakada C, Masaki T, Kume O, Shinohara T, et al. Role of leptin signaling in the pathogenesis of angiotensin II-mediated atrial fibrosis and fibrillation. <i>Circ Arrhythm Electrophysiol<\/i> 2013; 6: 402\u2013409.","DOI":"10.1161\/CIRCEP.111.000104"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Follmann M, Ackerstaff J, Redlich G, Wunder F, Lang D, Kern A, et al. Discovery of the soluble guanylate cyclase stimulator vericiguat (BAY 1021189) for the treatment of chronic heart failure. <i>J Med Chem<\/i> 2017; 60: 5146\u20135161.","DOI":"10.1021\/acs.jmedchem.7b00449"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Kondo H, Kira S, Oniki T, Gotoh K, Fukui A, Abe I, et al. 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Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. <i>Circ Res<\/i> 2011; 108: 837\u2013846.","DOI":"10.1161\/CIRCRESAHA.110.232306"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Schnee JM, Hsueh WA. Angiotensin II, adhesion, and cardiac fibrosis. <i>Cardiovasc Res<\/i> 2000; 46: 264\u2013268.","DOI":"10.1016\/S0008-6363(00)00044-4"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Zablocki D, Sadoshima J. Angiotensin II and oxidative stress in the failing heart. <i>Antioxid Redox Signal<\/i> 2013; 19: 1095\u20131109.","DOI":"10.1089\/ars.2012.4588"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Ikeda Y, Kumagai H, Motozawa Y, Suzuki J, Komuro I. Biased agonism of the angiotensin II type I receptor. <i>Int Heart J<\/i> 2015; 56: 485\u2013488.","DOI":"10.1536\/ihj.15-256"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Numata G, Takimoto E. 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