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Egan BM, Laken MA. Pre-hypertension: Rationale for pharmacotherapy. <i>Curr Hypertens Rep<\/i> 2013; 15: 669\u2013675.","DOI":"10.1007\/s11906-013-0387-7"},{"key":"2","unstructured":"2. Assadi F. Prehypertension: A warning sign of future cardiovascular risk. <i>Int J Prev Med<\/i> 2014; 5(Suppl 1): S4\u2013S9."},{"key":"3","unstructured":"3. Oza R, Garcellano M. Nonpharmacologic management of hypertension: What works? <i>Am Fam Physician<\/i> 2015; 91: 772\u2013776."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Turner JM, Spatz ES. Nutritional supplements for the treatment of hypertension: A practical guide for clinicians. <i>Curr Cardiol Rep<\/i> 2016; 18: 126.","DOI":"10.1007\/s11886-016-0806-x"},{"key":"5","unstructured":"5. Ohkubo T, Mihailidou AS. Is there a role for day-to-day home blood pressure variability in guiding management of hypertension? <i>Clin Exp Pharmacol Physiol<\/i> 2014; 41: 54\u201357."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. 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The Japanese Society of Hypertension Guidelines for the management of hypertension (JSH 2014). <i>Hypertens Res<\/i> 2014; 37: 253\u2013390.","DOI":"10.1038\/hr.2014.20"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Tomiyama H, Yamazaki M, Sagawa Y, Teraoka K, Shirota T, Miyawaki Y, et al. Synergistic effect of smoking and blood pressure on augmentation index in men, but not in women. <i>Hypertens Res<\/i> 2009; 32: 122\u2013126.","DOI":"10.1038\/hr.2008.20"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Yamashina A, Tomiyama H, Takeda K, Tsuda H, Arai T, Hirose K, et al. Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement. <i>Hypertens Res<\/i> 2002; 25: 359\u2013364.","DOI":"10.1291\/hypres.25.359"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Tomiyama H, Kohro T, Higashi Y, Takase B, Suzuki T, Ishizu T, et al. Reliability of measurement of endothelial function across multiple institutions and establishment of reference values in Japanese. <i>Atherosclerosis<\/i> 2015; 242: 433\u2013442.","DOI":"10.1016\/j.atherosclerosis.2015.08.001"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Tomiyama H, Yoshida M, Higashi Y, Takase B, Furumoto T, Kario K, et al; sub-group study of FMD-J. Autonomic nervous activation triggered during induction of reactive hyperemia exerts a greater influence on the measured reactive hyperemia index by peripheral arterial tonometry than on flow-mediated vasodilatation of the brachial artery in patients with hypertension. <i>Hypertens Res<\/i> 2014; 37: 914\u2013918.","DOI":"10.1038\/hr.2014.103"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Yoshizawa M, Maeda S, Miyaki A, Misono M, Choi Y, Shimojo N, et al. Additive beneficial effects of lactotripeptides intake with regular exercise on endothelium-dependent dilatation in postmenopausal women. <i>Am J Hypertens<\/i> 2010; 23: 368\u2013372.","DOI":"10.1038\/ajh.2009.270"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Yamasue K, Morikawa N, Mizushima S, Tochikubo O. The blood pressure lowering effect of lactotripeptides and salt intake in 24-h ambulatory blood pressure measurements. <i>Clin Exp Hypertens<\/i> 2010; 32: 214\u2013220.","DOI":"10.3109\/10641963.2010.491885"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Misu Y, Yue JL, Miyamae T, Goshima Y. Altered L-DOPA systems for blood pressure regulation in the lower brainstem of spontaneously hypertensive rats. <i>Hypertens Res<\/i> 1995; 18: 267\u2013277.","DOI":"10.1291\/hypres.18.267"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Chanson-Rolle A, Aubin F, Braesco V, Hamasaki T, Kitakaze M. Influence of the lactotripeptides isoleucine-proline-proline and valine-proline-proline on systolic blood pressure in Japanese subjects: A systematic review and meta-analysis of randomized controlled trials. <i>PLoS One<\/i> 2015; 10: e0142235.","DOI":"10.1371\/journal.pone.0142235"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Cicero AF, Aubin F, Azais-Braesco V, Borghi C. Do the lactotripeptides isoleucine-proline-proline and valine-proline-proline reduce systolic blood pressure in European subjects?: A meta-analysis of randomized controlled trials. <i>Am J Hypertens<\/i> 2013; 26: 442\u2013449.","DOI":"10.1093\/ajh\/hps044"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Cicero AF, Gerocarni B, Laghi L, Borghi C. Blood pressure lowering effect of lactotripeptides assumed as functional foods: A meta-analysis of current available clinical trials. <i>J Hum Hypertens<\/i> 2011; 25: 425\u2013436.","DOI":"10.1038\/jhh.2010.85"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Qin LQ, Xu JY, Dong JY, Zhao Y, van Bladeren P, Zhang W. Lactotripeptides intake and blood pressure management: A meta-analysis of randomised controlled clinical trials. <i>Nutr Metab Cardiovasc Dis<\/i> 2013; 23: 395\u2013402.","DOI":"10.1016\/j.numecd.2013.02.006"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Cicero AF, Rosticci M, Gerocarni B, Bacchelli S, Veronesi M, Strocchi E, et al. Lactotripeptides effect on office and 24-h ambulatory blood pressure, blood pressure stress response, pulse wave velocity and cardiac output in patients with high-normal blood pressure or first-degree hypertension: A randomized double-blind clinical trial. <i>Hypertens Res<\/i> 2011; 34: 1035\u20131040.","DOI":"10.1038\/hr.2011.92"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. van Mierlo LA, Koning MM, van der Zander K, Draijer R. Lactotripeptides do not lower ambulatory blood pressure in untreated whites: Results from 2 controlled multicenter crossover studies. <i>Am J Clin Nutr<\/i> 2009; 89: 617\u2013623.","DOI":"10.3945\/ajcn.2008.26918"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Engberink MF, Schouten EG, Kok FJ, van Mierlo LA, Brouwer IA, Geleijnse JM. 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