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Guidelines for the treatment of pulmonary hypertension (JCS 2017\/JPCPHS 2017). <i>Circ J<\/i> 2019; 83: 842\u2013945.","DOI":"10.1253\/circj.CJ-66-0158"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Humbert M, Kovacs G, Hoeper MM, Badagliacca R, Berger RMF, Brida M, et al. 2022 ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension. <i>Eur Heart J<\/i> 2022; 43: 3618\u20133731.","DOI":"10.1093\/eurheartj\/ehac237"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Hoeper MM, Benza RL, Corris P, de Perrot M, Fadel E, Keogh AM, et al. Intensive care, right ventricular support and lung transplantation in patients with pulmonary hypertension. <i>Eur Respir J<\/i> 2019; 53: 1801906.","DOI":"10.1183\/13993003.01906-2018"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Sitbon O, Jais X, Savale L, Cottin V, Bergot E, Macari EA, et al. Upfront triple combination therapy in pulmonary arterial hypertension: A pilot study. <i>Eur Respir J<\/i> 2014; 43: 1691\u20131697.","DOI":"10.1183\/09031936.00116313"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Tamura Y, Kumamaru H, Satoh T, Miyata H, Ogawa A, Tanabe N, et al. Effectiveness and outcome of pulmonary arterial hypertension-specific therapy in Japanese patients with pulmonary arterial hypertension. <i>Circ J<\/i> 2017; 82: 275\u2013282.","DOI":"10.1253\/circj.CJ-17-0139"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Bhorade S, Christenson J, O\u2019Connor M, Lavoie A, Pohlman A, Hall JB. Response to inhaled nitric oxide in patients with acute right heart syndrome. <i>Am J Respir Crit Care Med<\/i> 1999; 159: 571\u2013579.","DOI":"10.1164\/ajrccm.159.2.9804127"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Tremblay JA, Couture EJ, Albert M, Beaubien-Souligny W, Elmi-Sarabi M, Lamarche Y, et al. Noninvasive administration of inhaled nitric oxide and its hemodynamic effects in patients with acute right ventricular dysfunction. <i>J Cardiothorac Vasc Anesth<\/i> 2019; 33: 642\u2013647.","DOI":"10.1053\/j.jvca.2018.08.004"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Kitamukai O, Sakuma M, Takahashi T, Nawata J, Ikeda J, Shirato K. Hemodynamic effects of inhaled nitric oxide using pulse delivery and continuous delivery systems in pulmonary hypertension. <i>Intern Med<\/i> 2002; 41: 429\u2013434.","DOI":"10.2169\/internalmedicine.41.429"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Perez-Penate GM, Julia-Serda G, Ojeda-Betancort N, Garcia-Quintana A, Pulido-Duque J, Rodriguez-Perez A, et al. Long-term inhaled nitric oxide plus phosphodiesterase 5 inhibitors for severe pulmonary hypertension. <i>J Heart Lung Transplant<\/i> 2008; 27: 1326\u20131332.","DOI":"10.1016\/j.healun.2008.08.007"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Ogo T, Shimokawahara H, Kinoshita H, Sakao S, Abe K, Matoba S, et al. Selexipag for the treatment of chronic thromboembolic pulmonary hypertension. <i>Eur Respir J<\/i> 2022; 60: 2101694.","DOI":"10.1183\/13993003.01694-2021"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Simonneau G, D\u2019Armini AM, Ghofrani HA, Grimminger F, Hoeper MM, Jansa P, et al. Riociguat for the treatment of chronic thromboembolic pulmonary hypertension: A long-term extension study (CHEST-2). <i>Eur Respir J<\/i> 2015; 45: 1293\u20131302.","DOI":"10.1183\/09031936.00087114"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Perez-Penate GM, Julia-Serda G, Galvan-Fernandez H, Aleman-Segura D, Leon-Marrero F, Garcia-Quintana A, et al. Safety of inhaled nitric oxide withdrawal in severe chronic pulmonary hypertension. <i>Pulm Circ<\/i> 2024; 14: e12344.","DOI":"10.1002\/pul2.12344"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Frostell CG, Blomqvist H, Hedenstierna G, Lundberg J, Zapol WM. Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation. <i>Anesthesiology<\/i> 1993; 78: 427\u2013435.","DOI":"10.1097\/00000542-199303000-00005"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Griffiths MJ, Evans TW. Inhaled nitric oxide therapy in adults. <i>N Engl J Med<\/i> 2005; 353: 2683\u20132695.","DOI":"10.1056\/NEJMra051884"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Pocock SJ, Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. <i>Biometrics<\/i> 1975; 31: 103\u2013115.","DOI":"10.2307\/2529712"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Hashimoto K, Hashimoto A, Kishimoto M, Sugawara K, Funahashi H, Nakano K, et al. 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