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The role of inflammation and metabolic risk factors in the pathogenesis of calcific aortic valve stenosis. <i>Aging Clin Exp Res<\/i> 2021; 33: 1765\u20131770.","DOI":"10.1007\/s40520-020-01681-2"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Parisi V, Rengo G, Pagano G, D\u2019Esposito V, Passaretti F, Caruso A, et al. Epicardial adipose tissue has an increased thickness and is a source of inflammatory mediators in patients with calcific aortic stenosis. <i>Int J Cardiol<\/i> 2015; 186: 167\u2013169.","DOI":"10.1016\/j.ijcard.2015.03.201"},{"key":"9","unstructured":"9. Mahabadi AA, Kahlert HA, Dykun I, Balcer B, Kahlert P, Rassaf T. Epicardial adipose tissue thickness independently predicts severe aortic valve stenosis. <i>J Heart Valve Dis<\/i> 2017; 26: 262\u2013267."},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Eberhard M, Stocker D, Meyer M, Kebernik J, St\u00e4hli BE, Frauenfelder T, et al. Epicardial adipose tissue volume is associated with adverse outcomes after transcatheter aortic valve replacement. <i>Int J Cardiol<\/i> 2019; 286: 29\u201335.","DOI":"10.1016\/j.ijcard.2019.01.068"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kitagawa T, Sentani K, Ikegami Y, Takasaki T, Takahashi S, Nakano Y. Relationship between clinical parameters and histological features of epicardial adipose tissue and aortic valve calcification assessed on computed tomography. <i>Circ J<\/i> 2024; 88: 1986\u20131995.","DOI":"10.1253\/circj.CJ-24-0226"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Kitagawa T, Yamamoto H, Sentani K, Takahashi S, Tsushima H, Senoo A, et al. 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Sarin S, Wenger C, Marwaha A, Qureshi A, Go BD, Woomert CA, et al. Clinical significance of epicardial fat measured using cardiac multislice computed tomography. <i>Am J Cardiol<\/i> 2008; 102: 767\u2013771.","DOI":"10.1016\/j.amjcard.2008.04.058"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Baumgartner H, Hung J, Bermejo J, Chambers JB, Edvardsen T, Goldstein S, et al. Recommendations on the echocardiographic assessment of aortic valve stenosis: A focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. <i>J Am Soc Echocardiogr<\/i> 2017; 30: 372\u2013392.","DOI":"10.1016\/j.echo.2017.02.009"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Takahari K, Utsunomiya H, Itakura K, Yamamoto H, Nakano Y. 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Relationship of metabolic syndrome with incident aortic valve calcium and aortic valve calcium progression: The Multi-Ethnic Study of Atherosclerosis (MESA). <i>Diabetes<\/i> 2009; 58: 813\u2013819.","DOI":"10.2337\/db08-1515"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Pag\u00e9 A, Dumesnil JG, Clavel MA, Chan KL, Teo KK, Tam JW, et al. Metabolic syndrome is associated with more pronounced impairment of left ventricle geometry and function in patients with calcific aortic stenosis: A substudy of the ASTRONOMER (Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin). <i>J Am Coll Cardiol<\/i> 2010; 55: 1867\u20131874.","DOI":"10.1016\/j.jacc.2009.11.083"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Chen Y, Jia S, Zhang J, Han J, Zhang H, Jiang W. Calcific aortic valve disease: From mechanism to treatment. <i>Circ J<\/i> 2025; 89: 1447\u20131452.","DOI":"10.1253\/circj.CJ-24-0706"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Coisne A, Ninni S, Ortmans S, Davin L, Kasprzak K, Long\u00e8re B, et al. Epicardial fat amount is associated with the magnitude of left ventricular remodeling in aortic stenosis. <i>Int J Cardiovasc Imaging<\/i> 2019; 35: 267\u2013273.","DOI":"10.1007\/s10554-018-1477-z"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. 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