{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T18:09:07Z","timestamp":1648663747985},"reference-count":36,"publisher":"Japanese Pharmacological Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Folia Pharmacol. Jpn."],"published-print":{"date-parts":[[2001]]},"DOI":"10.1254\/fpj.118.51","type":"journal-article","created":{"date-parts":[[2004,4,13]],"date-time":"2004-04-13T06:04:58Z","timestamp":1081836298000},"page":"51-58","source":"Crossref","is-referenced-by-count":1,"title":["Pharmacological, pharmacokinetic and clinical properties of olopatadine hydrochloride (olopatadine), an antiallergic drug."],"prefix":"10.1254","volume":"118","author":[{"given":"Kenji","family":"OHMORI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihide","family":"IKEMURA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"KOBAYASHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akimichi","family":"MUKOUYAMA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"332","reference":[{"issue":"4","key":"1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1254\/fpj.106.289","volume":"106","author":"ISHII HIDEE","year":"1995","journal-title":"\u65e5\u85ac\u7406\u8a8c","ISSN":"http:\/\/id.crossref.org\/issn\/0015-5691","issn-type":"print"},{"issue":"10","key":"2","first-page":"1825","volume":"5","author":"SASAKI YASUO","year":"1995","journal-title":"\u85ac\u7406\u3068\u81e8\u5e8a","ISSN":"http:\/\/id.crossref.org\/issn\/0917-3994","issn-type":"print"},{"issue":"10","key":"3","first-page":"1817","volume":"5","author":"NONAKA HIROMI","year":"1995","journal-title":"\u85ac\u7406\u3068\u81e8\u5e8a","ISSN":"http:\/\/id.crossref.org\/issn\/0917-3994","issn-type":"print"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1994.2295"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(97)01620-8"},{"key":"6","first-page":"33","volume":"77","author":"Yanni JM, Sharif NA, Gamache DA, Mi","year":"1999","journal-title":"Acta Ophthamol Scand"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1006\/cimm.1996.0205"},{"key":"8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000237311","volume":"110","author":"Ikemura T, Manabe H, Sasaki Y, Ishi","year":"1996","journal-title":"Int Arch Allergy Immunol","ISSN":"http:\/\/id.crossref.org\/issn\/1018-2438","issn-type":"print"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1592.2001.00207.x"},{"issue":"5","key":"10","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1111\/j.1476-5381.1996.tb15289.x","volume":"117","year":"1996","journal-title":"Br J Pharmacol","ISSN":"http:\/\/id.crossref.org\/issn\/0007-1188","issn-type":"print"},{"issue":"2","key":"11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1254\/jjp.71.179","volume":"71","author":"IKEMURA T","year":"1996","journal-title":"Jpn J Pharmacol","ISSN":"http:\/\/id.crossref.org\/issn\/0021-5198","issn-type":"print"},{"issue":"14","key":"12","first-page":"3543","volume":"29","author":"ISHII HIDEE","year":"1995","journal-title":"\u57fa\u790e\u3068\u81e8\u5e8a","ISSN":"http:\/\/id.crossref.org\/issn\/0385-2806","issn-type":"print"},{"issue":"10","key":"13","first-page":"1229","volume":"44","author":"KAISE TOSHIHIKO","year":"1995","journal-title":"\u30a2\u30ec\u30eb\u30ae\u30fc","ISSN":"http:\/\/id.crossref.org\/issn\/0021-4884","issn-type":"print"},{"issue":"9","key":"14","first-page":"1005","volume":"45","year":"1995","journal-title":"Arzneimittelforschung","ISSN":"http:\/\/id.crossref.org\/issn\/0004-4172","issn-type":"print"},{"issue":"4","key":"15","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1254\/jjp.69.435","volume":"69","author":"KAISE T","year":"1995","journal-title":"Jpn J Pharmacol","ISSN":"http:\/\/id.crossref.org\/issn\/0021-5198","issn-type":"print"},{"key":"16","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1159\/000237312","volume":"110","author":"Ohmori K, Ishii H, Sasaki Y, Ikemur","year":"1996","journal-title":"Int Arch Allergy Immunol","ISSN":"http:\/\/id.crossref.org\/issn\/1018-2438","issn-type":"print"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/0306-3623(95)02004-7"},{"issue":"2","key":"18","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1254\/jjp.70.199","volume":"70","author":"KATO Y","year":"1996","journal-title":"Jpn J Pharmacol","ISSN":"http:\/\/id.crossref.org\/issn\/0021-5198","issn-type":"print"},{"issue":"16","key":"19","first-page":"4129","volume":"29","author":"TSUNOO MICHIO","year":"1995","journal-title":"\u57fa\u790e\u3068\u81e8\u5e8a","ISSN":"http:\/\/id.crossref.org\/issn\/0385-2806","issn-type":"print"},{"key":"20","first-page":"1","volume":"29","author":"Tateishi T, Kobayashi S, Shigeyama","year":"1998","journal-title":"Drugs Exp Clin Res","ISSN":"http:\/\/id.crossref.org\/issn\/0378-6501","issn-type":"print"},{"issue":"1","key":"21","first-page":"107","volume":"42","author":"KOSHIKAWA SHOZO","year":"1997","journal-title":"\u814e\u3068\u900f\u6790","ISSN":"http:\/\/id.crossref.org\/issn\/0385-2156","issn-type":"print"},{"issue":"5","key":"22","doi-asserted-by":"crossref","first-page":"651","DOI":"10.2133\/dmpk.10.651","volume":"10","author":"OISHI TAKAYOSHI","year":"1995","journal-title":"\u85ac\u7269\u52d5\u614b","ISSN":"http:\/\/id.crossref.org\/issn\/0916-1139","issn-type":"print"},{"issue":"10","key":"23","first-page":"1116","volume":"47","year":"1997","journal-title":"Arzneimittelforschung","ISSN":"http:\/\/id.crossref.org\/issn\/0004-4172","issn-type":"print"},{"key":"24","unstructured":"24) \u5965\u7530\u7a14, \u9ad8\u5742\u77e5\u7bc0, \u4e09\u5b85\u6d69\u90f7, \u539f\u7530\u5eb7\u592b, \u77f3\u5ddd\u54ee, \u72ac\u5c71\u5f81\u592b, \u9593\u53e3\u56db\u90ce, \u6734\u6ca2\u4e8c\u90ce, \u677e\u539f\u7be4, \u7a32\u6751\u76f4\u6a39\u307b\u304b: KW-4679 (olopatadine hydrochloride) \u306e\u901a\u5e74\u6027\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u524d\u671f\u7b2cII\u76f8\u8a66\u9a13. (\u793e\u5185\u8cc7\u6599)"},{"key":"25","unstructured":"25) \u5965\u7530\u7a14, \u9ad8\u5742\u77e5\u7bc0, \u4e09\u5b85\u6d69\u90f7, \u539f\u7530\u5eb7\u592b, \u77f3\u5ddd\u54ee, \u72ac\u5c71\u5f81\u592b, \u9593\u53e3\u56db\u90ce, \u5289\u6fa4\u5468, \u6734\u6ca2\u4e8c\u90ce, \u6c60\u91ce\u656c\u4e00\u307b\u304b: KW-4679 (olopatadine hydrochloride) \u306e\u901a\u5e74\u6027\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u5f8c\u671f\u7b2cII\u76f8\u8a66\u9a13-\u591a\u65bd\u8a2d\u4e8c\u91cd\u76f2\u691c\u6cd5\u306b\u3088\u308b\u81f3\u9069\u7528\u91cf\u306e\u691c\u8a0e-. (\u793e\u5185\u8cc7\u6599)"},{"key":"26","unstructured":"26) \u5965\u7530\u7a14, \u9ad8\u5742\u77e5\u7bc0, \u4e09\u5b85\u6d69\u90f7, \u539f\u7530\u5eb7\u592b, \u77f3\u5ddd\u54ee, \u72ac\u5c71\u5f81\u592b, \u9593\u53e3\u56db\u90ce, \u65b0\u5ddd\u79c0\u4e00, \u6c60\u91ce\u656c\u4e00, \u677e\u539f\u7be4\u307b\u304b: KW-4679 (olopatadine hydrochloride) \u306e\u901a\u5e74\u6027\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u8a55\u4fa1-Oxatomide\u3092\u5bfe\u7167\u85ac\u3068\u3057\u305f\u4e8c\u91cd\u76f2\u691c\u6bd4\u8f03\u8a66\u9a13-. (\u793e\u5185\u8cc7\u6599)"},{"issue":"2","key":"27","first-page":"191","volume":"17","author":"NISHIYAMA SHIGEO","year":"2001","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"2","key":"28","first-page":"211","volume":"17","author":"NISHIYAMA SHIGEO","year":"2001","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"2","key":"29","first-page":"237","volume":"17","author":"NISHIYAMA SHIGEO","year":"2001","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"8","key":"30","first-page":"1597","volume":"12","author":"NISHIYAMA SHIGEO","year":"1996","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"8","key":"31","first-page":"1615","volume":"12","author":"NISHIYAMA SHIGEO","year":"1996","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"8","key":"32","first-page":"1543","volume":"12","author":"MIYAMOTO TERUMASA","year":"1996","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"1","key":"33","first-page":"87","volume":"17","author":"MIYAMOTO TERUMASA","year":"2001","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"9","key":"34","first-page":"1915","volume":"12","author":"YAMAKIDO MICHIO","year":"1996","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"9","key":"35","first-page":"1935","volume":"12","author":"SANO YASUYUKI","year":"1996","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"},{"issue":"9","key":"36","first-page":"1883","volume":"12","author":"MIYAMOTO TERUMASA","year":"1996","journal-title":"\u81e8\u5e8a\u533b\u85ac","ISSN":"http:\/\/id.crossref.org\/issn\/0910-8211","issn-type":"print"}],"container-title":["Folia Pharmacologica Japonica"],"original-title":["????????????????????????????????????????"],"language":"ja","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/fpj\/118\/1\/118_1_51\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T16:08:41Z","timestamp":1621440521000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/fpj\/118\/1\/118_1_51\/_article\/-char\/ja\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001]]}},"URL":"https:\/\/doi.org\/10.1254\/fpj.118.51","relation":{},"ISSN":["0015-5691","1347-8397"],"issn-type":[{"value":"0015-5691","type":"print"},{"value":"1347-8397","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001]]}}}