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Drug Metab Pharmacokinet. 2018;33:31-39.","DOI":"10.1016\/j.dmpk.2017.11.001"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Ohtsuki S, et al. Drug Metab Dispos. 2014;42:1039-1043.","DOI":"10.1124\/dmd.114.057646"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Sanoh S, et al. Biopharm Drug Dispos. 2014;35:71-86.","DOI":"10.1002\/bdd.1864"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Sanoh S, et al. Drug Metab Dispos. 2012;40:2267-2272.","DOI":"10.1124\/dmd.112.047555"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Igawa Y, et al. Xenobiotica. 2014;44:154-163.","DOI":"10.3109\/00498254.2013.865857"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Dickie AP, et al. Biochem Pharmacol. 2017;135:139-150.","DOI":"10.1016\/j.bcp.2017.03.015"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Nakada N, et al. Xenobiotica. 2015;45:757-765.","DOI":"10.3109\/00498254.2015.1019594"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) De Serres M, et al. Xenobiotica. 2011;41:464-475.","DOI":"10.3109\/00498254.2011.560295"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Fan PW, et al. Drug Metab Dispos. 2016;44:1253-1261.","DOI":"10.1124\/dmd.116.070169"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Sodhi JK, et al. Drug Metab Dispos. 2015;43:908-915.","DOI":"10.1124\/dmd.114.061804"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Terao M, et al. Arch Toxicol. 2016;90:753-780.","DOI":"10.1007\/s00204-016-1683-1"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Sanoh S, et al. Drug Metab Pharmacokinet. 2015;30:52-63.","DOI":"10.1016\/j.dmpk.2014.10.009"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Kitamura S, et al. Drug Metab Dispos. 2008;36:1202-1205.","DOI":"10.1124\/dmd.107.019075"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Sanoh S, et al. Drug Metab Dispos. 2012;40:76-82.","DOI":"10.1124\/dmd.111.041954"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Tanoue C, et al. Xenobiotica. 2013;43:956-962.","DOI":"10.3109\/00498254.2013.788232"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Utoh R, et al. Am J Pathol. 2010;177:654-665.","DOI":"10.2353\/ajpath.2010.090430"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Liu L, et al. Drug Metab Dispos. 2011;39:1840-1849.","DOI":"10.1124\/dmd.111.040840"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Akabane T, et al. Xenobiotica. 2011;41:372-384.","DOI":"10.3109\/00498254.2010.549970"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Sanoh S, et al. Drug Metab Dispos. 2012;40:322-328.","DOI":"10.1124\/dmd.111.040923"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Sanoh S, et al. Xenobiotica. 2015;45:605-614.","DOI":"10.3109\/00498254.2015.1007112"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Miyamoto M, et al. Xenobiotica. 2017;47:1052-1063.","DOI":"10.1080\/00498254.2016.1265160"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Utoh M, et al. Xenobiotica. 2016;46:1049-1055.","DOI":"10.3109\/00498254.2016.1147102"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Hu Y, et al. Pharmacogenet Genomics. 2013;23:78-83.","DOI":"10.1097\/FPC.0b013e32835cb2c7"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Kamimura H, et al. Xenobiotica. 2017;47:382-393.","DOI":"10.1080\/00498254.2016.1199063"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Kato K, et al. 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Toxicol Res. 2015;4:106-111.","DOI":"10.1039\/C4TX00068D"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38) Schulz-Utermoehl T, et al. Xenobiotica. 2012;42:503-517.","DOI":"10.3109\/00498254.2011.640716"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39) Samuelsson K, et al. Xenobiotica. 2014;44:186-195.","DOI":"10.3109\/00498254.2013.879237"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40) Kakuni M, et al. Toxicol Lett. 2012;214:9-18.","DOI":"10.1016\/j.toxlet.2012.08.001"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41) Foster JR, et al. Toxicol Pathol. 2012;40:1106-1116.","DOI":"10.1177\/0192623312447542"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42) Xu D, et al. J Pharmacol Exp Ther. 2015;352:274-280.","DOI":"10.1124\/jpet.114.220798"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43) Okada K, et al. 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Toxicol Pathol. 2015;43:233-248.","DOI":"10.1177\/0192623314544378"},{"key":"50","doi-asserted-by":"crossref","unstructured":"51) Sanoh S, et al. J Toxicol Sci. 2017;42:589-596.","DOI":"10.2131\/jts.42.589"},{"key":"51","doi-asserted-by":"crossref","unstructured":"52) Chayama K, et al. J Gastroenterol Hepatol. 2011;26:13-18.","DOI":"10.1111\/j.1440-1746.2010.06470.x"},{"key":"52","doi-asserted-by":"crossref","unstructured":"54) Yoshizato K, et al. Expert Opin Drug Metab Toxicol. 2013;9:1419-1435.","DOI":"10.1517\/17425255.2013.826649"},{"key":"53","doi-asserted-by":"crossref","unstructured":"55) Kosaka K, et al. Biochem Biophys Res Commun. 2013;441:230-235.","DOI":"10.1016\/j.bbrc.2013.10.040"},{"key":"54","doi-asserted-by":"crossref","unstructured":"56) Kremsdorf D, et al. Curr Opin Virol. 2017;25:119-125.","DOI":"10.1016\/j.coviro.2017.07.029"},{"key":"55","doi-asserted-by":"crossref","unstructured":"57) Kikuchi R, et al. 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