{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T00:46:00Z","timestamp":1700786760699},"reference-count":61,"publisher":"Japanese Pharmacological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Folia Pharmacol. Jpn.","Folia Pharmacologica Japonica"],"published-print":{"date-parts":[[2022]]},"DOI":"10.1254\/fpj.22026","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T22:11:57Z","timestamp":1656627117000},"page":"271-279","source":"Crossref","is-referenced-by-count":0,"title":["Pharmacological actions of anifrolumab (Saphnelo&lt;sup&gt;\u00ae&lt;\/sup&gt;) and clinical trial results as a treatment for systemic lupus erythematosus","\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\uff08\u30b5\u30d5\u30cd\u30ed\u30fc&lt;sup&gt;\u00ae&lt;\/sup&gt;\u70b9\u6ef4\u9759\u6ce8300\u2005mg\uff09\u306e\u85ac\u7406\u5b66\u7684\u7279\u5fb4\u304a\u3088\u3073\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u8a66\u9a13\u6210\u7e3e"],"prefix":"10.1254","volume":"157","author":[{"given":"Takeshi","family":"Ueha","sequence":"first","affiliation":[{"name":"AstraZeneca K.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Kusuda","sequence":"additional","affiliation":[{"name":"AstraZeneca K.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoko","family":"Shibata","sequence":"additional","affiliation":[{"name":"AstraZeneca K.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Hirata","sequence":"additional","affiliation":[{"name":"AstraZeneca K.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoko","family":"Ozaki","sequence":"additional","affiliation":[{"name":"AstraZeneca K.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"332","reference":[{"key":"1","unstructured":"1) Nived O, et al. J Rheumatol. 2002;28:1398-1400."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Alarc\u00f3n GS, et al. Arthritis Rheum. 2004;51:465-474.","DOI":"10.1002\/art.20409"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Munoz LE, et al. Rheumatology (Oxford). 2005;44:1101-1107.","DOI":"10.1093\/rheumatology\/keh693"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Rahman A, et al. N Engl J Med. 2008;358:929-939.","DOI":"10.1056\/NEJMra071297"},{"key":"5","unstructured":"5) Yu Y, et al. J Clin Cell Immunol. 2013;4:139."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Mayadas TN, et al. Circulation. 2009;120:2012-2024.","DOI":"10.1161\/CIRCULATIONAHA.108.771170"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Weckerle CE, et al. Arthritis Rheum. 2011;63:1044-1053.","DOI":"10.1002\/art.30187"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Kirou KA, et al. Arthritis Rheu. 2005;52:1491-1503.","DOI":"10.1002\/art.21031"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Lichtman EI, et al. Clin Immunol. 2012;143:210-221.","DOI":"10.1016\/j.clim.2012.03.005"},{"key":"10","unstructured":"10) Psarras A, et al. Rheumatology (Oxford). 2017;56:1662-1675."},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Deng Y, et al. Curr Opin Rheumatol. 2014;26:482-492.","DOI":"10.1097\/BOR.0000000000000086"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Crow YJ, et al. Nat Rev Immunol. 2015;15:429-440.","DOI":"10.1038\/nri3850"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Ioannou Y, et al. Arthritis Rheum. 2000;43:1431-1442.","DOI":"10.1002\/1529-0131(200007)43:7<1431::AID-ANR3>3.0.CO;2-E"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Okanoue T, et al. J Hepatol. 1996;25:283-291.","DOI":"10.1016\/S0168-8278(96)80113-9"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Seillet C, et al. Blood. 2012;12:454-464.","DOI":"10.1002\/mabi.201100337"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Ytterberg SR, et al. Arthritis Rheum. 1982;25:401-406.","DOI":"10.1002\/art.1780250407"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Baechler EC, et al. Proc Natl Acad Sci U S A. 2003;100:2610-2615.","DOI":"10.1073\/pnas.0337679100"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Bengtsson AA, et al. Lupus. 2000;9:664-671.","DOI":"10.1191\/096120300674499064"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Chiche L, et al. Arthritis Rheum. 2014;66:1583-1595.","DOI":"10.1002\/art.38628"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Saadeh D, et al. Exp Dermatol. 2016;25:415-421.","DOI":"10.1111\/exd.12957"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Tucci M, et al. Arthritis Rheum. 2008;58:251-262.","DOI":"10.1002\/art.23186"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Shiozawa S, et al. Arthritis Rheum. 1992;35:417-422.","DOI":"10.1002\/art.1780350410"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Fairhurst AM, et al. Eur J Immunol. 2008;38:1948-1960.","DOI":"10.1002\/eji.200837925"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Theofilopoulos AN, et al. Annu Rev Immunol. 2005;23:307-336.","DOI":"10.1146\/annurev.immunol.23.021704.115843"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Liu YJ. Annu Rev Immunol. 2005;23:275-306.","DOI":"10.1146\/annurev.immunol.23.021704.115633"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Mogensen KE, et al. J Interferon Cytokine Res. 1999;19:1069-1098.","DOI":"10.1089\/107999099313019"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Stark GR, et al. Annu Rev Biochem. 1998;67:227-264.","DOI":"10.1146\/annurev.biochem.67.1.227"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Blanco P, et al. Science. 2001;294:1540-1543.","DOI":"10.1126\/science.1064890"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) B\u00e5ve U, et al. J Immunol. 2003;171:3296-3302.","DOI":"10.4049\/jimmunol.171.6.3296"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) L\u00f6vgren T, et al. Arthritis Rheum. 2004;50:1861-1872.","DOI":"10.1002\/art.20254"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Means TK, et al. J Clin Invest. 2005;115:407-417.","DOI":"10.1172\/JCI23025"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Vollmer J, et al. J Exp Med. 2005;202:1575-1585.","DOI":"10.1084\/jem.20051696"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Banchereau J, et al. Immunity. 2004;20:539-550.","DOI":"10.1016\/S1074-7613(04)00108-6"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Parlato S, et al. Blood. 2001;98:3022-3029.","DOI":"10.1182\/blood.V98.10.3022"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Axtell RC, et al. Clin Rev Allergy Immunol. 2013;44:114-120.","DOI":"10.1007\/s12016-011-8296-5"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36) Gangaplara A, et al. PLoS Pathog. 2018;14:e1006985.","DOI":"10.1371\/journal.ppat.1006985"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) Jego GAK, et al. Immunity. 2003;19:225-234.","DOI":"10.1016\/S1074-7613(03)00208-5"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38) Le Bon A, et al. J Immunol. 2006;176:2074-2078.","DOI":"10.4049\/jimmunol.176.4.2074"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39) Banchereau R, et al. Cell. 2016;165:551-565.","DOI":"10.1016\/j.cell.2016.03.008"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40) Bengtsson AA, et al. Best Pract Res Clin Rheumatol. 2017;31:415-428.","DOI":"10.1016\/j.berh.2017.10.003"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41) Riggs JM, et al. Lupus Sci Med. 2018;5:e000261.","DOI":"10.1136\/lupus-2018-000261"},{"key":"42","unstructured":"42) \u30a2\u30b9\u30c8\u30e9\u30bc\u30cd\u30ab\u793e\u5185\u8cc7\u6599\uff1a\u30b5\u30d5\u30cd\u30ed\u30fc (<i>In vitr<\/i>o\u7d50\u5408\u8a66\u9a13) (2021\u5e749\u670827\u65e5\u627f\u8a8d\uff0cCTD2.6.2.2.1.2)"},{"key":"43","unstructured":"43) \u30a2\u30b9\u30c8\u30e9\u30bc\u30cd\u30ab\u793e\u5185\u8cc7\u6599\uff1a\u30b5\u30d5\u30cd\u30ed\u30fc (\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u306e<i>in vitro<\/i>\u85ac\u7406\u8a66\u9a13) (2021\u5e749\u670827\u65e5\u627f\u8a8d\uff0cCTD2.6.2.2.1)"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44) Peng L, et al. MAbs. 2015;7:428-439.","DOI":"10.1080\/19420862.2015.1007810"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45) Wang B, et al. Clin Pharmacol Ther. 2013;93:483-492.","DOI":"10.1038\/clpt.2013.35"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46) Yao Y, et al. Arthritis Rheum. 2009;60:1785-1796.","DOI":"10.1002\/art.24557"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47) Canfield SM, et al. J Exp Med. 1991;173:1483-1491.","DOI":"10.1084\/jem.173.6.1483"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48) Chappel MS, et al. Proc Natl Acad Sci U S A. 1991;88:9036-9040.","DOI":"10.1073\/pnas.88.20.9036"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49) Idusogie EE, et al. J Immunol. 2000;164:4178-4184.","DOI":"10.4049\/jimmunol.164.8.4178"},{"key":"50","doi-asserted-by":"crossref","unstructured":"50) Hezareh MA, et al. J Virol. 2001;75:12161-12168.","DOI":"10.1128\/JVI.75.24.12161-12168.2001"},{"key":"51","unstructured":"51) \u30a2\u30b9\u30c8\u30e9\u30bc\u30cd\u30ab\u793e\u5185\u8cc7\u6599\uff1a\u30b5\u30d5\u30cd\u30ed\u30fc (<i>In vivo<\/i>\u30de\u30a6\u30b9\u8a66\u9a13) (2021\u5e749\u670827\u65e5\u627f\u8a8d\uff0cCTD2.6.2.2.2)"},{"key":"52","doi-asserted-by":"crossref","unstructured":"52) Delaney TA, et al. J Immunol. 2016;197:42-50.","DOI":"10.4049\/jimmunol.1502190"},{"key":"53","doi-asserted-by":"crossref","unstructured":"53) Morand EF, et al. N Engl J Med. 2020;382:211-221.","DOI":"10.1056\/NEJMoa1912196"},{"key":"54","doi-asserted-by":"crossref","unstructured":"54) Morand EF, et al. N Engl J Med. 2020;382:211-221. Supplemental Protocol.","DOI":"10.1056\/NEJMoa1912196"},{"key":"55","unstructured":"55) \u30a2\u30b9\u30c8\u30e9\u30bc\u30cd\u30ab\u793e\u5185\u8cc7\u6599\uff1a\u30b5\u30d5\u30cd\u30ed\u30fc (04\u8a66\u9a13\uff1a\u4e2d\u7b49\u75c7\u304b\u3089\u91cd\u75c7\u306e\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7b2c\u2162\u76f8\u56fd\u969b\u5171\u540c\u8a66\u9a13 (D3461C00004) (2021\u5e749\u670827\u65e5\u627f\u8a8d\uff0cCTD2.6.2.2.2)"},{"key":"56","doi-asserted-by":"crossref","unstructured":"56) Furie R, et al. Arthritis Rheumatol. 2017;69:376-386.","DOI":"10.1002\/art.39962"},{"key":"57","unstructured":"57) \u30a2\u30b9\u30c8\u30e9\u30bc\u30cd\u30ab\u793e\u5185\u8cc7\u6599\uff1a\u30b5\u30d5\u30cd\u30ed\u30fc (1013\u8a66\u9a13\uff1a\u4e2d\u7b49\u75c7\u304b\u3089\u91cd\u75c7\u306e\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7b2c\u2161\u76f8\u56fd\u969b\u5171\u540c\u8a66\u9a13 (CD-IA-MEDI-546-1013)) (2021\u5e749\u670827\u65e5\u627f\u8a8d\uff0cCTD2.7.6.2.3)"},{"key":"58","unstructured":"58) \u30a2\u30b9\u30c8\u30e9\u30bc\u30cd\u30ab\u793e\u5185\u8cc7\u6599\uff1a\u30b5\u30d5\u30cd\u30ed\u30fc (\u751f\u7269\u85ac\u5264\u5b66\u8a66\u9a13\u53ca\u3073\u95a2\u9023\u3059\u308b\u5206\u6790\u6cd5) (2021\u5e749\u670827\u65e5\u627f\u8a8d\uff0cCTD2.7.1)"},{"key":"59","doi-asserted-by":"crossref","unstructured":"59) Casey KA, et al. Lupus Sci Med. 2018;5:e000286.","DOI":"10.1136\/lupus-2018-000286"},{"key":"60","doi-asserted-by":"crossref","unstructured":"60) Smith MA, et al. Sci Rep. 2020;10:4462.","DOI":"10.1038\/s41598-020-65465-4"},{"key":"61","doi-asserted-by":"crossref","unstructured":"61) Casey KA, et al. Arthritis Rheum. 2021;73:459-471.","DOI":"10.1002\/art.41518"}],"container-title":["Folia Pharmacologica Japonica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/fpj\/157\/4\/157_22026\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T00:23:09Z","timestamp":1700785389000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/fpj\/157\/4\/157_22026\/_article\/-char\/ja\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1254\/fpj.22026","relation":{},"ISSN":["0015-5691","1347-8397"],"issn-type":[{"value":"0015-5691","type":"print"},{"value":"1347-8397","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"article-number":"22026"}}