{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T02:52:33Z","timestamp":1767149553353,"version":"build-2238731810"},"reference-count":17,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1980,1,1]],"date-time":"1980-01-01T00:00:00Z","timestamp":315532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,27]],"date-time":"2019-09-27T00:00:00Z","timestamp":1569542400000},"content-version":"vor","delay-in-days":14514,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Japanese Journal of Pharmacology"],"published-print":{"date-parts":[[1980]]},"DOI":"10.1016\/s0021-5198(19)31491-x","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T13:36:59Z","timestamp":1605620219000},"page":"221-229","source":"Crossref","is-referenced-by-count":4,"title":["Continuous Determination of Tracheobronchial Secretory Activity in Dogs"],"prefix":"10.1016","volume":"30","author":[{"given":"Miwa","family":"MISAWA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saizo","family":"YANAURA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0021-5198(19)31491-X_bib1","first-page":"153","article-title":"Expectorants","volume":"2","author":"Henderson","year":"1910","journal-title":"J. Pharmacol. exp. Ther"},{"key":"10.1016\/S0021-5198(19)31491-X_bib2","first-page":"779","article-title":"Pharmacological studies of expectorants, especially of the effect of autonomic nerve drugs on mucus secretions of the lower respiratory tract.","volume":"33","author":"Sakuno","year":"1940","journal-title":"J. Oriental Med"},{"key":"10.1016\/S0021-5198(19)31491-X_bib3","first-page":"65","article-title":"A method for studying expectorant action in animals by direct measurement of the output of respiratory tract fluids","volume":"73","author":"Perry","year":"1941","journal-title":"J. Pharmacol. exp. Ther"},{"key":"10.1016\/S0021-5198(19)31491-X_bib4","first-page":"777","article-title":"Pharmacological studies on a new mucolytic expectorant, S-carboxy-methyl-cysteine","volume":"12","author":"Yanaura","year":"1976","journal-title":"Pharmacometrics, Sendai"},{"key":"10.1016\/S0021-5198(19)31491-X_bib5","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1254\/jjp.28.391","article-title":"New method for evaluating bronchomotor and bron-chosecretory activities: Effects of prostaglandins and antigen","volume":"28","author":"Yamatake","year":"1978","journal-title":"Japan. J. Pharmacol"},{"key":"10.1016\/S0021-5198(19)31491-X_bib6","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1254\/fpj.70.447","article-title":"Pharmacological studies on measurement of secretion in the respiratory tract","volume":"70","author":"Yanaura","year":"1974","journal-title":"Folia pharmacol. japon"},{"key":"10.1016\/S0021-5198(19)31491-X_bib7","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1248\/bpb1978.2.127","article-title":"Direct effects of expectorants on the tracheobronchial system","volume":"2","author":"Misawa","year":"1979","journal-title":"in vivo. J. Pharm. Dyn."},{"key":"10.1016\/S0021-5198(19)31491-X_bib8","first-page":"346","article-title":"Ether anesthesia and the output of fluids from the respiratory tract.","volume":"79","author":"Boyd","year":"1943","journal-title":"J. Pharmacol. exp. Ther"},{"key":"10.1016\/S0021-5198(19)31491-X_bib9","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1254\/fpj.73.605","article-title":"Pharmacological studies on expectorants","volume":"73","author":"Kas\u00e9","year":"1977","journal-title":"Folia pharmacol. japon"},{"key":"10.1016\/S0021-5198(19)31491-X_bib10","first-page":"741","article-title":"The canine tracheal pouch\u2014A model for use in respiratory mucus research","volume":"101","author":"Wardell","year":"1970","journal-title":"Am. Rev. Resp. Dis"},{"key":"10.1016\/S0021-5198(19)31491-X_bib11","series-title":"Respiratory Tract Fluid","first-page":"209","author":"Boyd","year":"1972"},{"key":"10.1016\/S0021-5198(19)31491-X_bib12","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1042\/cs0430533","article-title":"An organ culture study of the effect of drugs on the secretory activities of the human bronchial submucosal gland","volume":"43","author":"Sturgess","year":"1972","journal-title":"Clin. Sci"},{"key":"10.1016\/S0021-5198(19)31491-X_bib13","first-page":"388","article-title":"The effect of isoprenaline and pilocarpine on (a) bronchial mucussecreting tissue and (b) pancreas, salivary glands, heart, thymus, liver and spleen","volume":"54","author":"Sturgess","year":"1973","journal-title":"Brit. J. exp. Pathol"},{"key":"10.1016\/S0021-5198(19)31491-X_bib14","first-page":"521","article-title":"Expectorants and respiratory tract fluids","volume":"6","author":"Boyd","year":"1954","journal-title":"Pharmacol. Rev"},{"key":"10.1016\/S0021-5198(19)31491-X_bib15","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.2042-7158.1964.tb07430.x","article-title":"The expectorant action of cephaeline, emetine and 2-dehydroemetine","volume":"16","author":"Boyd","year":"1964","journal-title":"J. Pharm. Pharmacol"},{"key":"10.1016\/S0021-5198(19)31491-X_bib16","series-title":"International Encyclopedia of Pharmacology and Therapeutics","first-page":"760","author":"Lish","year":"1970"},{"key":"10.1016\/S0021-5198(19)31491-X_bib17","first-page":"124","article-title":"The expectorant action of creosote and the guaiacols","volume":"48","author":"Stevens","year":"1946","journal-title":"Canad. med. Ass. J"}],"container-title":["Japanese Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002151981931491X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002151981931491X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T12:37:28Z","timestamp":1618403848000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002151981931491X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980]]},"references-count":17,"aliases":["10.1254\/jjp.30.221"],"journal-issue":{"issue":"2","published-print":{"date-parts":[[1980]]}},"alternative-id":["S002151981931491X"],"URL":"https:\/\/doi.org\/10.1016\/s0021-5198(19)31491-x","relation":{},"ISSN":["0021-5198"],"issn-type":[{"value":"0021-5198","type":"print"}],"subject":[],"published":{"date-parts":[[1980]]}}}