{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T02:53:13Z","timestamp":1767149593948,"version":"build-2238731810"},"reference-count":19,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1983,1,1]],"date-time":"1983-01-01T00:00:00Z","timestamp":410227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T00:00:00Z","timestamp":1570492800000},"content-version":"vor","delay-in-days":13429,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Japanese Journal of Pharmacology"],"published-print":{"date-parts":[[1983]]},"DOI":"10.1016\/s0021-5198(19)60167-8","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T07:37:42Z","timestamp":1605685062000},"page":"253-256","source":"Crossref","is-referenced-by-count":5,"title":["CARDIOVASCULAR EFFECTS OF MICROINJECTION OF MORPHINE INTO THE NUCLEUS LOCUS COERULEUS OF THE CAT"],"prefix":"10.1016","volume":"33","author":[{"given":"Kamlesh K.","family":"PANT","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil","family":"GURTU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devendra K.","family":"SHARMA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagdish N.","family":"SINHA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna P.","family":"BHARGAVA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0021-5198(19)60167-8_bib1","first-page":"1","article-title":"Evidence for the existence of monoamine neurones in the central nervous system","volume":"64","author":"Dahlstrom","year":"1965","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/S0021-5198(19)60167-8_bib2","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0006-8993(69)90185-1","article-title":"Projections of the nucleus locus coeruleus in the albino rat","volume":"15","author":"Loizou","year":"1969","journal-title":"Brain Res."},{"key":"10.1016\/S0021-5198(19)60167-8_bib3","series-title":"Advances in Biochemical Pharmacol","first-page":"51","article-title":"Immunohisto-chemical distribution of enkephalin neurones","author":"Johanssan","year":"1978"},{"key":"10.1016\/S0021-5198(19)60167-8_bib4","series-title":"Opiates and Endogenous Opioid Peptides","first-page":"199","article-title":"Microiontophoretic study of the effects of opiates on autoradiographically located opiate receptors","author":"Bird","year":"1976"},{"key":"10.1016\/S0021-5198(19)60167-8_bib5","series-title":"Developments in Opiate Research","first-page":"107","article-title":"Endogenous ligands of opiate receptors (Endorphins)","author":"Teschemacher","year":"1978"},{"key":"10.1016\/S0021-5198(19)60167-8_bib6","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1212\/WNL.25.3.223","article-title":"Biochemical mapping of the noradrenergic projection from the locus coeruleus","volume":"25","author":"Kobayashi","year":"1975","journal-title":"Neurology"},{"key":"10.1016\/S0021-5198(19)60167-8_bib7","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/0006-8993(70)90246-5","article-title":"Direct hypothalamic projections to the locus coeruleus","volume":"19","author":"Mizuno","year":"1970","journal-title":"Brain Res."},{"key":"10.1016\/S0021-5198(19)60167-8_bib8","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1152\/ajplegacy.1968.214.2.258","article-title":"Vagal cardioinhibitory mechanisms in the hind brain of the dog and cat","volume":"214","author":"Gunn","year":"1968","journal-title":"Am. J. Physiol."},{"key":"10.1016\/S0021-5198(19)60167-8_bib9","first-page":"658","article-title":"Activation of solitary nucleus neurones from the locus coeruleus and vicinity","author":"Ward","year":"1975","journal-title":"Neuroscience, Abs."},{"key":"10.1016\/S0021-5198(19)60167-8_bib10","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/0024-3205(71)90333-X","article-title":"Selective action of 6-hydroxydopa on noradrenergic terminals: Mapping of preterminal axons of the brain","volume":"10","author":"Jacobowitz","year":"1971","journal-title":"Life Sci."},{"key":"10.1016\/S0021-5198(19)60167-8_bib11","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0006-8993(72)90763-9","article-title":"Projections ascendantes du locus coeruleus et d\u2019autres neurones aminergiques pontiques au niveau du prosencephale du rat","volume":"36","author":"Maeda","year":"1972","journal-title":"Brain Res."},{"key":"10.1016\/S0021-5198(19)60167-8_bib12","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0006-8993(72)90299-5","article-title":"Further mapping out of central noradrenaline systems: Projections of the subcoeruleus area","volume":"43","author":"Olson","year":"1972","journal-title":"Brain Res."},{"key":"10.1016\/S0021-5198(19)60167-8_bib13","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/cne.901560205","article-title":"Connections of the median and dorsal raphe nuclei in the rat: An auto-radiographic and degeneration study","volume":"156","author":"Conard","year":"1974","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/S0021-5198(19)60167-8_bib14","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0006-8993(77)90515-7","article-title":"Serotonergic innervation of noradrenergic neurones in nucleus locus coeruleus: demonstration by immunohistochemical localization of the transmitter specific enzyme tyrosine hydroxylase and tryptophan hydroxylase","volume":"131","author":"Pickel","year":"1977","journal-title":"Brain Res."},{"key":"10.1016\/S0021-5198(19)60167-8_bib15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0006-8993(78)90243-3","article-title":"Cardiovascular alteration by nucleus locus coeruleus in spontaneously hypertensive rat","volume":"140","author":"Kawamura","year":"1978","journal-title":"Brain Res."},{"key":"10.1016\/S0021-5198(19)60167-8_bib16","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/BF00501184","article-title":"Reduced pressor responses to stimulation of locus coeruleus after lesion of the posterior hypothalamus","volume":"276","author":"Przuntek","year":"1973","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/S0021-5198(19)60167-8_bib17","article-title":"A Stereotaxic Atlas of Cat Brain","author":"Snider","year":"1961","journal-title":"The University of Chicago Press"},{"key":"10.1016\/S0021-5198(19)60167-8_bib18","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/279013a0","article-title":"Clinical relevance of opiate receptors and opioid peptide research","volume":"279","author":"Snider","year":"1979","journal-title":"Nature"},{"key":"10.1016\/S0021-5198(19)60167-8_bib19","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1126\/science.7384811","article-title":"Opiates and opioid peptides hyperpolarise locus coeruleus neurones in vitro","volume":"209","author":"Pepper","year":"1980","journal-title":"Science"}],"container-title":["Japanese Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021519819601678?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021519819601678?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T07:37:47Z","timestamp":1605685067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021519819601678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983]]},"references-count":19,"aliases":["10.1254\/jjp.33.253"],"journal-issue":{"issue":"1","published-print":{"date-parts":[[1983]]}},"alternative-id":["S0021519819601678"],"URL":"https:\/\/doi.org\/10.1016\/s0021-5198(19)60167-8","relation":{},"ISSN":["0021-5198"],"issn-type":[{"value":"0021-5198","type":"print"}],"subject":[],"published":{"date-parts":[[1983]]}}}