{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T10:06:44Z","timestamp":1648807604504},"reference-count":13,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1986,1,1]],"date-time":"1986-01-01T00:00:00Z","timestamp":504921600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T00:00:00Z","timestamp":1569369600000},"content-version":"vor","delay-in-days":12320,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Japanese Journal of Pharmacology"],"published-print":{"date-parts":[[1986]]},"DOI":"10.1254\/jjp.41.415","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T04:54:36Z","timestamp":1201150476000},"page":"416-419","source":"Crossref","is-referenced-by-count":1,"title":["Copper-Induced Alteration of Muscarinic Binding in Bovine Adrenal Medulla"],"prefix":"10.1016","volume":"41","author":[{"given":"Kyozo","family":"YAMANAKA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"KIGOSHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikunobu","family":"MURAMATSU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1254\/jjp.41.415_bib1","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/283090a0","article-title":"Pirenzepine distinguishes between different subclasses of muscarinic receptors","volume":"283","author":"Hammer","year":"1980","journal-title":"Nature"},{"key":"10.1254\/jjp.41.415_bib2","doi-asserted-by":"crossref","first-page":"2991","DOI":"10.1016\/0024-3205(82)90066-2","article-title":"Muscarinic receptor subtypes M1 and M2 biochemical and functional characterization","volume":"31","author":"Hammer","year":"1982","journal-title":"Life Set"},{"key":"10.1254\/jjp.41.415_bib3","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1016\/0024-3205(82)90041-8","article-title":"[3H]Pirenzepme selectively identifies a high affinity population of muscannic cholinergic recopiors in the rat cerebral cortex","volume":"31","author":"Watson","year":"1982","journal-title":"Life Sci."},{"key":"10.1254\/jjp.41.415_bib4","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1016\/0024-3205(83)90652-5","article-title":"A unique regulatory profile and regional distribution of (3H)pirenzepine binding in the rat provide evidence for distinct M1 and M2 muscarinic receptor subtypes","volume":"32","author":"Watson","year":"1983","journal-title":"Life So."},{"key":"10.1254\/jjp.41.415_bib5","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0041-008X(79)90432-0","article-title":"Transition and heavy metal inhibition of Itgand binding to muscarinic acetylcholine receptors from rat brain","volume":"48","author":"Aronatam","year":"1979","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1254\/jjp.41.415_bib6","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1016\/0006-2952(84)90206-5","article-title":"Effects of copper on the binding of agonists and antagonists to muscarinic receptors in rat brain","volume":"33","author":"Farrar","year":"1984","journal-title":"Biochem, Pharmacol"},{"key":"10.1254\/jjp.41.415_bib7","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0006-291X(84)91444-X","article-title":"Copper ions and diamide induce a high affinity guantne-nucleoiide-inseneilive state for muscarinic agonists","volume":"120","author":"Gurwitz","year":"1984","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1254\/jjp.41.415_bib8","first-page":"3654","article-title":"Recognition of the muscarinic receptor by its endogenous neurotransmitter Binding of [3H]-acetylcholine and its modulation by transition metal ions and guanine nucleotides","volume":"81","author":"Gurwitz","year":"1984","journal-title":"Proc. NaB. Acad So USA."},{"key":"10.1254\/jjp.41.415_bib9","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/0006-291X(83)90412-6","article-title":"Differential regulation of high-affinity agonist binding to muscarinic sites in the rat heart, cerebellum and cerebral cortox","volume":"118","author":"Vickroy","year":"1983","journal-title":"BiochemJ Biophys. Res. Commun."},{"key":"10.1254\/jjp.41.415_bib10","unstructured":"Yamanaka, K., Kigoshi, S. and Muramatsu, I.: Muscarinic receptor subtypes in bovine adrenal; medulla. Biochem. Pharmacol (1986) (in press)"},{"key":"10.1254\/jjp.41.415_bib11","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Follin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1254\/jjp.41.415_bib12","series-title":"Neurotransmitter Receptor Binding","first-page":"57","article-title":"Methods in binding studies","author":"Bennet","year":"1978"},{"key":"10.1254\/jjp.41.415_bib13","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/0003-2697(80)90515-1","article-title":"Ligand A versatile computerized approach for characterization of hgand-binding systems","volume":"107","author":"Munson","year":"1980","journal-title":"Anal Biochem."}],"container-title":["Japanese Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021519819521552?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021519819521552?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T14:19:58Z","timestamp":1630592398000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021519819521552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1986]]}},"alternative-id":["S0021519819521552"],"URL":"https:\/\/doi.org\/10.1254\/jjp.41.415","relation":{},"ISSN":["0021-5198"],"issn-type":[{"value":"0021-5198","type":"print"}],"subject":[],"published":{"date-parts":[[1986]]}}}