{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T01:43:41Z","timestamp":1695865421909},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1990,1,1]],"date-time":"1990-01-01T00:00:00Z","timestamp":631152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T00:00:00Z","timestamp":1567728000000},"content-version":"vor","delay-in-days":10840,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Japanese Journal of Pharmacology"],"published-print":{"date-parts":[[1990]]},"DOI":"10.1254\/jjp.54.171","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T05:03:34Z","timestamp":1201151014000},"page":"171-178","source":"Crossref","is-referenced-by-count":2,"title":["Changes in Brain Lipid Composition in Thiamine Deficient Rats"],"prefix":"10.1016","volume":"54","author":[{"given":"Masako","family":"OKAZAKI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideharu","family":"SAKAMOTO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"OHTSUKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuji","family":"OGUCHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1254\/jjp.54.171_bib1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1749-6632.1982.tb31191.x","article-title":"Beriberi caused by antithiamin factors in food and its prevention","volume":"378","author":"Vimokesant","year":"1982","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1254\/jjp.54.171_bib2","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/oxfordjournals.alcalc.a044888","article-title":"Effect of chronic ethanol administration on thiamine transport in microvillous vesicles of rat small intestine","volume":"24","author":"Gastaldi","year":"1989","journal-title":"Alcohol Alcohol."},{"key":"10.1254\/jjp.54.171_bib3","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1254\/fpj.76.553","article-title":"Effect of pyrithiamine on rat sciatic nerve. (1) Morphological changes during the early stage of thiamine deficiency","volume":"76","author":"Oguchi","year":"1980","journal-title":"Folia Pharmacol. Japon."},{"key":"10.1254\/jjp.54.171_bib4","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1254\/fpj.76.567","article-title":"Effect of pyrithiamine on rat sciatic nerve. (2) Morphological changes during the last stage of thiamine deficiency","volume":"76","author":"Oguchi","year":"1980","journal-title":"Folia Pharmacol. Japon."},{"key":"10.1254\/jjp.54.171_bib5","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1254\/fpj.79.293","article-title":"Effect of oxythiamine on rat peripheral nerve.\u2014Morphological changes in sciatic nerve and plantar nerve of thiamine deficiency","volume":"79","author":"Kato","year":"1982","journal-title":"Folia Pharmacol. Japon."},{"key":"10.1254\/jjp.54.171_bib6","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1749-6632.1982.tb31211.x","article-title":"Medical and neurological aspects of thiamin: An introduction","volume":"378","author":"Dreyfus","year":"1982","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1254\/jjp.54.171_bib7","series-title":"Thiamine","first-page":"353","article-title":"Subacute necrotizing encephalomyelopathy","author":"Cooper","year":"1976"},{"key":"10.1254\/jjp.54.171_bib8","series-title":"The Wernicke-Korsakoff Syndrome","first-page":"72","article-title":"Pathological findings","author":"Victor","year":"1971"},{"key":"10.1254\/jjp.54.171_bib9","series-title":"Thiamine","first-page":"229","article-title":"Thiamine-deficiency encephalopathy: Thoughts on its pathogenesis","author":"Dreyfus","year":"1976"},{"key":"10.1254\/jjp.54.171_bib10","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0014-4800(78)90012-6","article-title":"Pyrithiamine-induced acute thiamine-deficient encephalopathy in the mouse","volume":"28","author":"Watanabe","year":"1978","journal-title":"Exp. Mol. Pathol."},{"key":"10.1254\/jjp.54.171_bib11","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1254\/fpj.74.991","article-title":"Effect of oxythiamine and pyrithiamine on rat brain\u2014Morphological changes in the thiamine deficient rat brain","volume":"74","author":"Oguchi","year":"1978","journal-title":"Folia Pharmacol. Japon."},{"key":"10.1254\/jjp.54.171_bib12","first-page":"77","article-title":"Reversible Impairment of cerebral DNA synthesis in thiamine deficiency","volume":"86","author":"Henderson","year":"1975","journal-title":"J. Lab. Clin. Med."},{"key":"10.1254\/jjp.54.171_bib13","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the Isolation and purification of total lipides from animal tissues","volume":"226","author":"Folch","year":"1957","journal-title":"J. Biol. Chem."},{"key":"10.1254\/jjp.54.171_bib14","series-title":"Lipids and Steroidhormones in Clinical Medicine","first-page":"9","article-title":"Method for determination of total serum lipids","author":"Bragdon","year":"1960"},{"key":"10.1254\/jjp.54.171_bib15","series-title":"Thiamine","first-page":"261","article-title":"The morphology of myelin degeneration in thiamine deficiency","author":"Collins","year":"1976"},{"key":"10.1254\/jjp.54.171_bib16","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1254\/jjp.32.775","article-title":"Effect of a single, large dose injection of pyrithiamin on the thiamin deficiency of the mouse","volume":"32","author":"Oguchi","year":"1982","journal-title":"Japan. J. Pharmacol."},{"key":"10.1254\/jjp.54.171_bib17","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0006-8993(79)90494-3","article-title":"Effect of thiamine deficiency of brain serotonin turnover","volume":"179","author":"Woert","year":"1979","journal-title":"Brain Res."},{"key":"10.1254\/jjp.54.171_bib18","first-page":"537","article-title":"Impairment of behavior and acetylcholine metabolism in thiamine deficiency","volume":"217","author":"Barclay","year":"1981","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1254\/jjp.54.171_bib19","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0005-2736(80)90120-0","article-title":"Effects of chronic consumption of ethanol and low-thiamin, low-protein diets on the lipid composition of rat whole brain and brain membranes","volume":"596","author":"Moscatelli","year":"1980","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1254\/jjp.54.171_bib20","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1471-4159.1975.tb11887.x","article-title":"Brain lipid composition of immature thiamin-deficient and undernourished rats","volume":"24","author":"Geel","year":"1975","journal-title":"J. Neurochem."},{"key":"10.1254\/jjp.54.171_bib21","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1172\/JCI105912","article-title":"Encephalopathy of thiamine deficiency: Studies of intracerebral mechanisms","volume":"47","author":"McCandless","year":"1968","journal-title":"J. Clin. Invest."},{"key":"10.1254\/jjp.54.171_bib22","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/0304-4165(65)90222-9","article-title":"The effect of thiamine deficiency on the pyruvate decarboxylase system on the central nervous system","volume":"104","author":"Dreyfus","year":"1965","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1254\/jjp.54.171_bib23","first-page":"1","article-title":"Thiamine metabolism in the experimental magnesium deficient rat. (III) Lipid synthesis in magnesium deficient rat. Studies with C-acetate and C-glucose","volume":"48","author":"Itokawa","year":"1974","journal-title":"Vitamin"},{"key":"10.1254\/jjp.54.171_bib24","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1016\/0006-2952(73)90023-3","article-title":"Effects of thiamin antagonists on drug hydroxylation and properties of cytochrome p-450 in the rat","volume":"22","author":"Wade","year":"1973","journal-title":"Biochem. Pharmacol."},{"key":"10.1254\/jjp.54.171_bib25","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/jn\/81.2.147","article-title":"Distribution and phosphorylation of oxythiamine in rat tissues","volume":"81","author":"Rindi","year":"1963","journal-title":"J. Nutr."},{"key":"10.1254\/jjp.54.171_bib26","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1254\/fpj.78.529","article-title":"Effect of oxythiamine and pyrithiamine on thiamine levels in the blood, liver and urine of rats","volume":"78","author":"Hobara","year":"1981","journal-title":"Folia Pharmacol. Japon."},{"key":"10.1254\/jjp.54.171_bib27","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/jn\/101.6.731","article-title":"Biochemical factors involved in the anorexia of thiamin deficiency in rats","volume":"101","author":"Bai","year":"1971","journal-title":"J. Nutr."},{"key":"10.1254\/jjp.54.171_bib28","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3177\/jnsv.24.105","article-title":"Lipogenesis in the brain of thiamine-deficient rat pups","volume":"24","author":"Trostler","year":"1978","journal-title":"J. Nutr. Sci. Vitaminol."},{"key":"10.1254\/jjp.54.171_bib29","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1152\/ajplegacy.1976.230.4.1101","article-title":"Thiamine transport in the central nervous system","volume":"230","author":"Spector","year":"1976","journal-title":"Am. J. Physiol."}],"container-title":["Japanese Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021519819327866?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021519819327866?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T14:21:48Z","timestamp":1630592508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021519819327866"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990]]}},"alternative-id":["S0021519819327866"],"URL":"https:\/\/doi.org\/10.1254\/jjp.54.171","relation":{},"ISSN":["0021-5198"],"issn-type":[{"value":"0021-5198","type":"print"}],"subject":[],"published":{"date-parts":[[1990]]}}}