{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T11:05:45Z","timestamp":1775905545393,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T00:00:00Z","timestamp":1565222400000},"content-version":"vor","delay-in-days":6428,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Japanese Journal of Pharmacology"],"published-print":{"date-parts":[[2002]]},"DOI":"10.1254\/jjp.89.296","type":"journal-article","created":{"date-parts":[[2002,8,26]],"date-time":"2002-08-26T16:44:18Z","timestamp":1030380258000},"page":"296-301","source":"Crossref","is-referenced-by-count":8,"title":["Inhibitory Effects of Metals on ATP-Induced Current Through P2X7 Receptor in NG108-15 Cells"],"prefix":"10.1016","volume":"89","author":[{"given":"Tomokazu","family":"Watano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isao","family":"Matsuoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1254\/jjp.89.296_bib1","first-page":"855","article-title":"Extracellular ATP stimulates adenylyl cyclase and phospholipase C through distinct purinoceptors in NG108-15 cells","volume":"47","author":"Matsuoka","year":"1995","journal-title":"Mol Pharmacol"},{"key":"10.1254\/jjp.89.296_bib2","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1046\/j.1471-4159.1996.67010398.x","article-title":"ATP-activated nonselective cation current in NG108-15 cells","volume":"67","author":"Kaiho","year":"1996","journal-title":"J Neurochem"},{"key":"10.1254\/jjp.89.296_bib3","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.1152\/jn.1997.77.5.2717","article-title":"Effects of anions on ATP-activated nonselective cation current in NG108-15 cells","volume":"77","author":"Kaiho","year":"1997","journal-title":"J Neurophysiol"},{"key":"10.1254\/jjp.89.296_bib4","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1046\/j.1471-4159.1998.70030951.x","article-title":"Identification of P2X7 (P2Z) receptor in N18TG-2 cells and NG108-15 cells","volume":"70","author":"Kaiho","year":"1998","journal-title":"J Neurochem"},{"key":"10.1254\/jjp.89.296_bib5","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/PL00005237","article-title":"Inhibition of ATP-induced cAMP formation by 5\u2032-\/)-fluorosulfonylbenzoyl-adenosine in NG108-15 cells","volume":"358","author":"Ohkubo","year":"1998","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1254\/jjp.89.296_bib6","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1038\/sj.bjp.0703168","article-title":"Effects of AMP derivatives on cyclic AMP levels in NG108-15 cells","volume":"129","author":"Ohkubo","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1254\/jjp.89.296_bib7","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1254\/jjp.84.325","article-title":"Correlation between adenine nucleotide-induced cyclic AMP elevation and extracellular adenosine formation in NG108-15 cells","volume":"84","author":"Ohkubo","year":"2000","journal-title":"Jpn J Pharmacol"},{"key":"10.1254\/jjp.89.296_bib8","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1111\/j.1471-4159.1993.tb09816.x","article-title":"Extracellular ATP stimulates calcium influx in neuroblastoma \u03c7 glioma hybrid NG108-15 cells","volume":"61","author":"Chueh","year":"1993","journal-title":"J Neurochem"},{"key":"10.1254\/jjp.89.296_bib9","first-page":"532","article-title":"Two distinct ATP signaling mechanisms in differentiated neuroblastoma \u03c7 glioma hybrid NG108-15 cells","volume":"45","author":"Chueh","year":"1994","journal-title":"Mol Pharmacol"},{"key":"10.1254\/jjp.89.296_bib10","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1254\/jjp.78.269","article-title":"Effects of YT-146[2-(1-Octynyl) adenosine], an adenosine A2A receptor agonist, on cAMP production and noradrenaline release in PC12 cells","volume":"78","author":"Ono","year":"1998","journal-title":"Jpn J Pharmacol"},{"key":"10.1254\/jjp.89.296_bib11","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/S0021-9258(19)83641-4","article-title":"A new generation of Ca2+ indicators with greatly improved fluorescence properties","volume":"260","author":"Grynkiewicz","year":"1985","journal-title":"J Biol Chem"},{"key":"10.1254\/jjp.89.296_bib12","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1074\/jbc.273.1.133","article-title":"Receptor-activated Ca2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK)293 cells. Evidence for a non-capacitative Ca2+ entry","volume":"273","author":"Zhu","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1254\/jjp.89.296_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1469-7793.2001.0001m.x","article-title":"Regulation of Drosophila transient receptor potential-like (TrpL) channels by phospholipase C-dependent mechanisms","volume":"530","author":"Estacion","year":"2001","journal-title":"J Physiol (Lond)"},{"key":"10.1254\/jjp.89.296_bib14","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1111\/j.1476-5381.1996.tb15293.x","article-title":"Full sensitivity of P2X2 purinoceptor to ATP revealed by changing extracellular pH","volume":"117","author":"King","year":"1996","journal-title":"Br J Pharmacol"},{"key":"10.1254\/jjp.89.296_bib15","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S0028-3908(99)00141-0","article-title":"P2Y receptors contribute to ATP-induced increases in intracellular calcium in differentiated but not undifferentiated PC12 cells","volume":"39","author":"Arslan","year":"2000","journal-title":"Neuropharmacology"},{"key":"10.1254\/jjp.89.296_bib16","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/PL00005328","article-title":"Ionic effects on human recombinatn P2X7 receptor function","volume":"39","author":"Michel","year":"1999","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1254\/jjp.89.296_bib17","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/sj.bjp.0703302","article-title":"Apparent species differences in the kinetic properties of P2X7 receptors","volume":"130","author":"Hibell","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1254\/jjp.89.296_bib18","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1074\/jbc.273.5.2653","article-title":"Activation of P2Y2 receptors by UTP and ATP stimulates mitogen-activated kinase activity through a pathway that involves related adhesion focal tyrosine kinase and protein kinase C","volume":"273","author":"Soltoff","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1254\/jjp.89.296_bib19","doi-asserted-by":"crossref","first-page":"19965","DOI":"10.1074\/jbc.273.32.19965","article-title":"ATP-stimulated activation of the mitogen-activated protein kinases through ion-otrophic P2X2 purinoreceptors in PC12 cells. Difference in purinoreceptor sensitivity in two PC12 cell lines","volume":"273","author":"Swanson","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1254\/jjp.89.296_bib20","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1111\/j.1476-5381.1996.tb15771.x","article-title":"Selectivity and activity of adenine dinucleotides at recombinant P2X2 and P2Yi purinoceptors","volume":"119","author":"Pintor","year":"1996","journal-title":"Br J Pharmacol"},{"key":"10.1254\/jjp.89.296_bib21","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1042\/bj1880789","article-title":"The ATP4- receptor of rat mast cells","volume":"188","author":"Cockcroft","year":"1980","journal-title":"Biochem J"},{"key":"10.1254\/jjp.89.296_bib22","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1113\/jphysiol.1996.sp021777","article-title":"Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells","volume":"497","author":"Evans","year":"1996","journal-title":"J Physiol (Lond)"},{"key":"10.1254\/jjp.89.296_bib23","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0003-9861(92)90010-T","article-title":"The ATP4- receptor-operated ion channel of human lymphocytes: inhibition of ion fluxes by amiloride analogs and by extracellular sodium ions","volume":"292","author":"Wiley","year":"1992","journal-title":"Arch Biochem Biophys"},{"key":"10.1254\/jjp.89.296_bib24","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1113\/jphysiol.1984.sp015517","article-title":"Isolation of calcium current and its sensitivity to monovalent cations in dialysed ventricular cells of guinea-pig","volume":"357","author":"Matsuda","year":"1984","journal-title":"J Physiol (Lond)"},{"key":"10.1254\/jjp.89.296_bib25","doi-asserted-by":"crossref","first-page":"7149","DOI":"10.1073\/pnas.82.20.7149","article-title":"The Ca channel in skeletal muscle is a large pore","volume":"82","author":"McCleskey","year":"1985","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1254\/jjp.89.296_bib26","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0006-3495(87)83371-4","article-title":"Monovalent ion current through single calcium channels of skeletal muscle transverse tubules","volume":"51","author":"Coronado","year":"1987","journal-title":"Biophys J"}],"container-title":["Japanese Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021519819301155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021519819301155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T05:41:52Z","timestamp":1622094112000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021519819301155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002]]}},"alternative-id":["S0021519819301155"],"URL":"https:\/\/doi.org\/10.1254\/jjp.89.296","relation":{},"ISSN":["0021-5198"],"issn-type":[{"value":"0021-5198","type":"print"}],"subject":[],"published":{"date-parts":[[2002]]}}}