{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:40:04Z","timestamp":1762875604838},"reference-count":16,"publisher":"Japanese Pharmacological Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pharmacol Sci"],"published-print":{"date-parts":[[2014]]},"DOI":"10.1254\/jphs.14001sc","type":"journal-article","created":{"date-parts":[[2014,4,24]],"date-time":"2014-04-24T00:24:10Z","timestamp":1398299050000},"page":"112-115","source":"Crossref","is-referenced-by-count":23,"title":["Involvement of the Long-Chain Fatty Acid Receptor GPR40 in Depression-Related Behavior"],"prefix":"10.1254","volume":"125","author":[{"given":"Takashi","family":"Nishinaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Nakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiyo","family":"Kasuya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shogo","family":"Tokuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"332","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1 Wall R, Ross RP, Fitzgerald GF, Stanton C. Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids. Nutr Rev. 2010;68:280\u2013289.","DOI":"10.1111\/j.1753-4887.2010.00287.x"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 McNamara RK, Strawn JR. Role of long-chain omega-3 fatty acids in psychiatric practice. PharmaNutrition. 2013;1:41\u201349.","DOI":"10.1016\/j.phanu.2012.10.004"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, et al. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem. 2003;278:11303\u2013113011.","DOI":"10.1074\/jbc.M211495200"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Itoh Y, Kawamata Y, Harada M, Kobayashi M, Fujii R, Fukusumi S, et al. Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature. 2003;422:173\u2013176.","DOI":"10.1038\/nature01478"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 Nakamoto K, Nishinaka T, Matsumoto K, Kasuya F, Mankura M, Koyama Y, et al. Involvement of the long-chain fatty acid receptor GPR40 as a novel pain regulatory system. Brain Res. 2012;1432:74\u201383.","DOI":"10.1016\/j.brainres.2011.11.012"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Boneva NB, Yamashima T. New insights into \u201cGPR40-CREB interaction in adult neurogenesis\u201d specific for primates. Hippocampus. 2012;22:896\u2013905.","DOI":"10.1002\/hipo.20951"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci. 2002;22:3251\u20133261.","DOI":"10.1523\/JNEUROSCI.22-08-03251.2002"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, Pandey GN. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry. 2003;60:804\u2013815.","DOI":"10.1001\/archpsyc.60.8.804"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 Ohira H, Fujioka Y, Katagiri C, Mamoto R, Aoyama-Ishikawa M, Amako K, et al. Butyrate attenuates inflammation and lipolysis generated by the interaction of adipocytes and macrophages. J Atheroscler Thromb. 2013;20:425\u2013442.","DOI":"10.5551\/jat.15065"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Hashimoto M, Hossain S. Neuroprotective and ameliorative actions of polyunsaturated fatty acids against neuronal diseases: beneficial effect of docosahexaenoic acid on cognitive decline in Alzheimer\u2019s disease. J Pharmacol Sci. 2011;116:150\u2013162.","DOI":"10.1254\/jphs.10R33FM"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Cao D, Kevala K, Kim J, Moon HS, Jun SB, Lovinger D, et al. Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function. J Neurochem. 2009;111:510\u2013521.","DOI":"10.1111\/j.1471-4159.2009.06335.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Hamazaki K, Choi KH, Kim HY. Phospholipid profile in the postmortem hippocampus of patients with schizophrenia and bipolar disorder: no changes in docosahexaenoic acid species. J Psychiatr Res. 2010;44:688\u2013693.","DOI":"10.1016\/j.jpsychires.2009.11.017"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Umhau JC, Zhou W, Carson RE, Rapoport SI, Polozova A, Demar J, et al. Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography. J Lipid Res. 2009;50:1259\u20131268.","DOI":"10.1194\/jlr.M800530-JLR200"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Porsolt RD, Le Pichon M, Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature. 1977;266:730\u2013732.","DOI":"10.1038\/266730a0"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15 Lin DC, Guo Q, Luo J, Zhang J, Nguyen K, Chen M, et al. Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor. Mol Pharmacol. 2012;82:843\u2013598.","DOI":"10.1124\/mol.112.079640"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Yabuki C, Komatsu H, Tsujihata Y, Maeda R, Ito R, Matsuda-Nagasumi K, et al. A novel antidiabetic drug, fasiglifam\/TAK-875, acts as an ago-allosteric modulator of FFAR1. PLoS One. 2013;8:e76280.","DOI":"10.1371\/journal.pone.0076280"}],"container-title":["Journal of Pharmacological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jphs\/125\/1\/125_14001SC\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T15:11:24Z","timestamp":1621437084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jphs\/125\/1\/125_14001SC\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1254\/jphs.14001sc","relation":{},"ISSN":["1347-8613","1347-8648"],"issn-type":[{"value":"1347-8613","type":"print"},{"value":"1347-8648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}