{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T15:44:34Z","timestamp":1791042274419,"version":"4.1.0"},"reference-count":32,"publisher":"Japanese Pharmacological Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pharmacol Sci"],"published-print":{"date-parts":[[2007]]},"DOI":"10.1254\/jphs.fm0070050","type":"journal-article","created":{"date-parts":[[2007,10,17]],"date-time":"2007-10-17T05:49:54Z","timestamp":1192600194000},"page":"145-150","source":"Crossref","is-referenced-by-count":47,"title":["Life Style-Related Diseases of the Digestive System: Cell Culture System for the Screening of Anti-Hepatitis C Virus (HCV) Reagents: Suppression of HCV Replication by Statins and Synergistic Action With Interferon"],"prefix":"10.1254","volume":"105","author":[{"given":"Masanori","family":"Ikeda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"332","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1 Hayashi N, Takehara T. Antiviral therapy for chronic hepatitis C: past, present, and future. J Gastroenterol. 2006;41:17–27.","DOI":"10.1007\/s00535-005-1740-7"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21232"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.03.062"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.02.138"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1126\/science.285.5424.110"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.8.4008-4021.2002"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.5.3181-3190.2003"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.6.2997-3006.2002"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1038\/sj.embor.embor840"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Wakita T, Pietschmann T, Kato T, Date T, Miyamoto M, Zhao Z, et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med. 2005;11:791–796.","DOI":"10.1038\/nm1268"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1126\/science.1114016"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0503596102"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/0270-9139(95)90083-7"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0510727103"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409666102"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.7.4160-4168.2003"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2004.03.034"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.45.120403.095748"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2005.04.004"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Molina S, Castet V, Fournier-Wirth C, Pichard-Garcia L, Avner R, Harats D, et al. The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus. J Hepatol. 2007;46:411–419.","DOI":"10.1016\/j.jhep.2006.09.024"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21 von Hahn T, McKeating JA. In vitro veritas? The challenges of studying hepatitis C virus infectivity in a test tube. J Hepatol. 2007;46:355–358.","DOI":"10.1016\/j.jhep.2006.12.004"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22 Sakamoto H, Okamoto K, Aoki M, Kato H, Katsume A, Ohta A, et al. Host sphingolipid biosynthesis as a target for hepatitis C virus therapy. Nat Chem Biol. 2005;1:333–337.","DOI":"10.1038\/nchembio742"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.05.085"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.04.019"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25 Yano M, Ikeda M, Abe K, Dansako H, Ohkoshi S, Aoyagi Y, et al. Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture. Antimicrob Agents Chemother. 2007;51:2016–2027.","DOI":"10.1128\/AAC.01426-06"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409834102"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2237238100"},{"issue":"3","key":"28","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0022-3565(24)29609-9","volume":"297","author":"NAKAI D","year":"2001","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3565","issn-type":"print"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29 Kocarek TA, Dahn MS, Cai H, Strom SC, Mercer-Haines NA. Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. Drug Metab Dispos. 2002;30:1400–1405.","DOI":"10.1124\/dmd.30.12.1400"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1086\/382595"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31 Kim SS, Peng LF, Lin W, Choe WH, Sakamoto N, Schreiber SL, et al. A cell-based, high-throughput screen for small molecule regulators of hepatitis C virus replication. Gastroenterology. 2007;132:311–320.","DOI":"10.1053\/j.gastro.2006.10.032"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32 O’Leary JG, Chan JL, McMahon CM, Chung RT. Atorvastatin does not exhibit antiviral activity against HCV at conventional doses: a pilot clinical trial. Hepatology. 2007;45:895–898.","DOI":"10.1002\/hep.21554"}],"container-title":["Journal of Pharmacological Sciences"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T18:15:17Z","timestamp":1737483317000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jphs\/105\/2\/105_2_145\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1254\/jphs.fm0070050","relation":{},"ISSN":["1347-8613","1347-8648"],"issn-type":[{"value":"1347-8613","type":"print"},{"value":"1347-8648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}