{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T05:00:24Z","timestamp":1773810024009,"version":"3.50.1"},"reference-count":27,"publisher":"Japanese Pharmacological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pharmacol Sci"],"published-print":{"date-parts":[[2006]]},"DOI":"10.1254\/jphs.fp0060380","type":"journal-article","created":{"date-parts":[[2006,8,21]],"date-time":"2006-08-21T05:35:42Z","timestamp":1156138542000},"page":"329-334","source":"Crossref","is-referenced-by-count":9,"title":["Vascular Reactivity to Various Vasoconstrictor Agents and Endothelium-Dependent Relaxations of Rat Thoracic Aorta in the Long-Term Period of Pinealectomy"],"prefix":"10.1254","volume":"101","author":[{"given":"Zehra","family":"Kurcer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Engin","family":"Sahna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ercument","family":"Olmez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"332","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1 Vanecek J. Celluler mechanisms of melatonin action. Physiol Rev. 1998;78:687–721.","DOI":"10.1152\/physrev.1998.78.3.687"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Sack RL, Lewy AJ, Erb DL, Vollmer WM, Singer CM. Human melatonin production decreases with age. J Pineal Res. 1986;3:379–388.","DOI":"10.1111\/j.1600-079X.1986.tb00760.x"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Zeitzer JM, Daniels JE, Duffy JF. Do plasma melatonin concentrations decline with age? Am J Med. 1999;107:432–436.","DOI":"10.1016\/S0002-9343(99)00266-1"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Sack RL, Lewy AJ, Hughes RJ. Use of melatonin for sleep and circadian rhythm disorders. Ann Med. 1998;30:115–121.","DOI":"10.3109\/07853899808999393"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 Zanaboni A, Forni A, Zanaboni-Muciaccia W, Zanussi C. Effect of pinealectomy on arterial blood pressure and food and water intake in the rat. J Endocrinol Inves. 1978;1:125–130.","DOI":"10.1007\/BF03350359"},{"issue":"3","key":"6","first-page":"360","volume":"56","year":"1976","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1188","issn-type":"print"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Birau N, Pettersson V, Meyer C, Gottschalk J. Hypotensive effect of melatonin in essential hypertension. IRCS Med Sci Biochem. 1981;9:906–962.","DOI":"10.1016\/B978-0-08-026400-4.50006-2"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Arangino S, Cagnaccia A, Vacco A M, Longu G, Volpe A, et al. Effects of melatonin on vascular reactivity, catecholamine levels, and blood pressure in healthy men. Am J Cardiol. 1999;83:1417–1419.","DOI":"10.1016\/S0002-9149(99)00112-5"},{"issue":"3","key":"9","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1139\/y80-049","volume":"58","year":"1980","ISSN":"https:\/\/id.crossref.org\/issn\/0008-4212","issn-type":"print"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Sahna E, Olmez E, Acet A. Effects of physiological and pharmacological concentrations of melatonin on ischemia-reperfusion arrhythmias in rats: Can the incidence of sudden cardiac death be reduced? J Pineal Res. 2002;32:194–198.","DOI":"10.1034\/j.1600-079x.2002.1o853.x"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Sahna E, Acet A, Ozer MK, Olmez E. Myocardial ischemia-reperfusion in rats: reduction of infarct size by either supplemental physiological or pharmacological doses of melatonin. J Pineal Res. 2002;33:234–238.","DOI":"10.1034\/j.1600-079X.2002.02924.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Kuszak J, Rodin M. A new technique of pinealectomy for adult rats. Experientia. 1977;33:283–284.","DOI":"10.1007\/BF02124114"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Grace MS, Cahill GM, Besharse JC. Melatonin deacetylation: retinal vertebrate class distribution and Xenopus laevis tissue distribution. Brain Res. 1991;559:56–63.","DOI":"10.1016\/0006-8993(91)90286-5"},{"key":"14","unstructured":"14 Sewerynek E. Melatonin and the cardiovascular system. Neuro Endocrinol Lett. 2002;23:79–83."},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/0306-3623(91)90435-9"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/0306-3623(91)90589-X"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Pache M, Krauchi K, Haefliger IO, Wirz-Justice A, Flammer J, Meyer P. Effect of melatonin on vascular responses of porcine ciliary arteries. Curr Eye Res. 2002;24:313–317.","DOI":"10.1076\/ceyr.24.4.313.8416"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Muck AO, Seeger H, Bartsch C, Lippert TH. Does melatonin affect calcium influx in human aortic smooth muscle cells and estradiol-mediated calcium antagonism? J Pineal Res. 1996;20:145–147.","DOI":"10.1111\/j.1600-079X.1996.tb00250.x"},{"issue":"1","key":"19","first-page":"34","volume":"207","year":"1994","ISSN":"https:\/\/id.crossref.org\/issn\/0037-9727","issn-type":"print"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980;288:373–376.","DOI":"10.1038\/288373a0"},{"key":"21","unstructured":"21 Furchgott RF. Studies on relaxation of rabbit aorta by sodium nitrite: The basis for the proposal that the acid-activated inhibitory factor from bovine retractor penis is inorganic nitrite and the endothelium-derived relaxing factor is nitric oxide. In: Vanhoutte PM, editor. Vasodilatasyon: vascular smooth muscle. Peptides, autonomic nerves and endothelium. New York: Raven Press; 1988. p. 401–414."},{"key":"22","unstructured":"22 Ignarro LJ, Bryns RE, Woods KS. Biochemical and pharmacological properties of EDRF and its similarity to nitric oxide radical. In: Vanhoutte PM, editor. Vasodilatasyon: vascular smooth muscle. Peptides, autonomic nerves and endothelium. New York: Raven Press; 1988. p. 427–435."},{"key":"23","doi-asserted-by":"crossref","unstructured":"23 Paskaloglu K, Sener G, Ayanoglu-Dulger G. Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum. Eur J Pharmacol. 2004;499:345–354.","DOI":"10.1016\/j.ejphar.2004.08.002"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24 Pogan L, Bissonnette P, Parent L, Sauve R. The effects of melatonin on Ca2+<\/sup> homeostasis in endothelial cells. J Pineal Res. 2002;33:37–47.","DOI":"10.1034\/j.1600-079X.2002.01890.x"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-3623(97)00090-6"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26 Reyes-Toso CF, Roson MI, Albornoz LE, Aran M, Pinto JE, Rodriguez RR, et al. Vascular reactivity in diabetic rats: effect of melatonin. J Pineal Res. 2002;33:81–86.","DOI":"10.1034\/j.1600-079X.2002.01886.x"},{"issue":"8","key":"27","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1038\/sj.bjp.0701761","volume":"123","year":"1998","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1188","issn-type":"print"}],"container-title":["Journal of Pharmacological Sciences"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T15:15:46Z","timestamp":1621437346000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jphs\/101\/4\/101_4_329\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.1254\/jphs.fp0060380","relation":{},"ISSN":["1347-8613","1347-8648"],"issn-type":[{"value":"1347-8613","type":"print"},{"value":"1347-8648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}