{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T07:02:57Z","timestamp":1775890977762,"version":"3.50.1"},"reference-count":15,"publisher":"Japanese Pharmacological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pharmacol Sci"],"published-print":{"date-parts":[[2008]]},"DOI":"10.1254\/jphs.sc0080027","type":"journal-article","created":{"date-parts":[[2008,4,21]],"date-time":"2008-04-21T05:52:16Z","timestamp":1208757136000},"page":"663-666","source":"Crossref","is-referenced-by-count":9,"title":["Decreased Expression of Angiotensin II Type 1 and Type 2 Receptors in the Brain After Long-Term Administration of Antihypertensive Drugs in Stroke-Prone Spontaneously Hypertensive Rat"],"prefix":"10.1254","volume":"106","author":[{"given":"Yayoi","family":"Nishida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumi","family":"Sugahara-Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouichi","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Asai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"332","reference":[{"issue":"3","key":"1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0031-6997(24)01458-3","volume":"52","author":"DE GASPARO M","year":"2000","ISSN":"https:\/\/id.crossref.org\/issn\/0031-6997","issn-type":"print"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Siragy HM. The role of the AT2 receptor in hypertension. Am J Hypertens. 2000;13:62S–67S.","DOI":"10.1016\/S0895-7061(00)00274-0"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-006-0190-8"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Ando H, Jezova M, Zhou J, Saavedra JM. Angiotensin II AT1 receptor blockade decreases brain artery inflammation in a stress-prone rat strain. Ann N Y Acad Sci. 2004;1018:345–350.","DOI":"10.1196\/annals.1296.043"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 McKinley MJ, McAllen RM, Pennington GL, Smardencas A, Weisinger RS, Oldfield BJ. Physiological actions of angiotensin II mediated by AT1 and AT2 receptors in the brain. Clin Exp Pharmacol Physiol Suppl. 1996;3:S99–S104.","DOI":"10.1111\/j.1440-1681.1996.tb02821.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/0169-328X(95)00309-G"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0705448"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbrainres.2004.01.008"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 Takahashi Y, Ishii Y, Nishida Y, Ikarashi M, Nagata T, Nakamura T, et al. Detection of aberrations of ubiquitin-conjugating enzyme E2C gene (UBE2C) in advanced colon cancer with liver metastases by DNA microarray and two-color FISH. Cancer Genet Cytogenet. 2006;168:30–35.","DOI":"10.1016\/j.cancergencyto.2005.12.011"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Takahashi Y, Masuda H, Ishii Y, Nishida Y, Kobayashi M, Asai S. Decreased expression of thioredoxin interacting protein mRNA in inflamed colonic mucosa in patients with ulcerative colitis. Oncol Rep. 2007;18:531–535.","DOI":"10.3892\/or.18.3.531"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Zhang X, Hintze TH. Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent. Circulation. 1998;97:576–580.","DOI":"10.1161\/01.CIR.97.6.576"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Inada Y, Wada T, Ojima M, Sanada T, Shibouta Y, Kanagawa R, et al. Protective effects of candesartan cilexetil (TCV-116) against stroke, kidney dysfunction and cardiac hypertrophy in stroke-prone spontaneously hypertensive rats. Clin Exp Hypertens. 1997;19:1079–1099.","DOI":"10.3109\/10641969709083206"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(01)01071-2"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1210\/me.2006-0005"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000229648.67883.f9"}],"container-title":["Journal of Pharmacological Sciences"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T20:47:17Z","timestamp":1738183637000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jphs\/106\/4\/106_SC0080027\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1254\/jphs.sc0080027","relation":{},"ISSN":["1347-8613","1347-8648"],"issn-type":[{"value":"1347-8613","type":"print"},{"value":"1347-8648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008]]}}}