{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:40:58Z","timestamp":1777434058602,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2003,7,1]],"date-time":"2003-07-01T00:00:00Z","timestamp":1057017600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Biochem"],"published-print":{"date-parts":[[2003,7,1]]},"abstract":"<jats:p>\n                    Nephrotoxicity from non-steroidal anti-inflammatory drugs (NSAID) is well recognized. We report a case of severe hypokalaemia and weakness due to renal tubular acidosis in a young woman who was taking 40-60 tablets per day of Nurofen Plus\n                    <jats:sup>\u00ae<\/jats:sup>\n                    (ibuprofen 200 mg and codeine phosphate 12\u00b78 mg). Proprietary brands of ibuprofen are freely available to the public and those containing codeine may be potentially subject to abuse. This case highlights the need to be aware of this potential and of the life-threatening electrolyte and acid-base disturbances that might be encountered with the widespread availability of these types of NSAID.\n                  <\/jats:p>","DOI":"10.1258\/000456303766477101","type":"journal-article","created":{"date-parts":[[2003,7,8]],"date-time":"2003-07-08T17:13:32Z","timestamp":1057684412000},"page":"422-423","source":"Crossref","is-referenced-by-count":32,"title":["Severe hypokalaemia and weakness due to Nurofen\n                    <sup>\u00ae<\/sup>\n                    misuse"],"prefix":"10.1177","volume":"40","author":[{"given":"R.","family":"Chetty","sequence":"first","affiliation":[{"name":"Department of Clinical Biochemistry, Russells Hall Hospital, Dudley DY1 2HQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Baoku","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Mildner","sequence":"additional","affiliation":[{"name":"Department of Medicine Russells Hall Hospital Dudley DY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Department of Medicine Russells Hall Hospital Dudley DY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Vallance","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Haddon","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Labib","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,7,1]]},"container-title":["Annals of Clinical Biochemistry: International Journal of Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/000456303766477101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/000456303766477101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:52:41Z","timestamp":1777377161000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/000456303766477101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,7,1]]}},"alternative-id":["10.1258\/000456303766477101"],"URL":"https:\/\/doi.org\/10.1258\/000456303766477101","relation":{},"ISSN":["0004-5632","1758-1001"],"issn-type":[{"value":"0004-5632","type":"print"},{"value":"1758-1001","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,7,1]]}}}