{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:41:39Z","timestamp":1777434099220,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2004,9,1]],"date-time":"2004-09-01T00:00:00Z","timestamp":1093996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Biochem"],"published-print":{"date-parts":[[2004,9,1]]},"abstract":"<jats:p>We report the case of a 56-year-old woman with a 7-year history of metastatic cancer who presented with severe copper deficiency following self-treatment with the copper-chelating agent tetrathiomolybdate. This compound was used with the aim of inhibiting tumour angiogenesis and was obtained from the USA by placing an order on the internet. The patient exhibited severe neutropenia as her serum copper concentration fell from 19.8 \u03bcmol\/L to 3.3 \u03bcmol\/L and her caeruloplasmin concentration from 35 mg\/dL to 4 mg\/dL.<\/jats:p>","DOI":"10.1258\/0004563041731574","type":"journal-article","created":{"date-parts":[[2004,8,21]],"date-time":"2004-08-21T20:55:26Z","timestamp":1093121726000},"page":"417-420","source":"Crossref","is-referenced-by-count":2,"title":["Iatrogenic copper deficiency following information and drugs obtained over the internet"],"prefix":"10.1177","volume":"41","author":[{"given":"TF","family":"Lang","sequence":"first","affiliation":[{"name":"Department of Clinical Biochemistry, The John Radcliffe Hospital, Oxford, OX3 9DU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Glynne-Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Blake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JDS","family":"Kay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,9,1]]},"container-title":["Annals of Clinical Biochemistry: International Journal of Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/0004563041731574","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/0004563041731574","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:52:58Z","timestamp":1777377178000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/0004563041731574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,9,1]]}},"alternative-id":["10.1258\/0004563041731574"],"URL":"https:\/\/doi.org\/10.1258\/0004563041731574","relation":{},"ISSN":["0004-5632","1758-1001"],"issn-type":[{"value":"0004-5632","type":"print"},{"value":"1758-1001","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,9,1]]}}}