{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:50:58Z","timestamp":1777434658319,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Biochem"],"published-print":{"date-parts":[[2007,1,1]]},"abstract":"\n Background: Angiotensin II (AngII), through the AngII type 2 receptor (AT\n 2<\/jats:sub>\n -R), might exert some effect on adipocyte-and lipogenesis-related biology. The Adenine\/Cytosine 3123 (A\/C\n 3123<\/jats:sup>\n ) polymorphism in the AT\n 2<\/jats:sub>\n -R gene is reportedly involved in some diseases, such as hypertension.\n <\/jats:p>\n \n Methods: A total of 201 healthy Japanese women (mean age 43.2 years) were enrolled in the study to investigate the association among the AT\n 2<\/jats:sub>\n -R A\/C\n 3123<\/jats:sup>\n polymorphism detected by polymerase chain reaction methods, body mass index (BMI) and other obesity-linked metabolic parameters (blood pressure, serum lipid\/lipoprotein, plasma glucose).\n <\/jats:p>\n \n Results: Homozygotes of the C-allele in the AT\n 2<\/jats:sub>\n -R A\/C\n 3123<\/jats:sup>\n polymorphism were associated with small but significant increases in BMI levels. There were no differences between genotype-based groups in the obesity-linked metabolic parameters.\n <\/jats:p>\n \n Conclusion: These findings suggest that the AT\n 2<\/jats:sub>\n -R A\/C\n 3123<\/jats:sup>\n polymorphism could be a polymorphic marker related to BMI in Japanese women.\n <\/jats:p>","DOI":"10.1258\/000456307779595959","type":"journal-article","created":{"date-parts":[[2007,1,20]],"date-time":"2007-01-20T10:49:36Z","timestamp":1169290176000},"page":"83-85","source":"Crossref","is-referenced-by-count":9,"title":["The angiotensin II type 2 receptor gene polymorphism and body mass index in healthy Japanese women"],"prefix":"10.1177","volume":"44","author":[{"given":"Kazuhiko","family":"Kotani","sequence":"first","affiliation":[{"name":"Division of Health Administration and Promotion, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan; Department of Preventive Medicine, Clinical Research Institute for Endocrine and Metabolic Disease, National Hospital\r Organization Kyoto Medical Center, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Sakane","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Clinical Research Institute for Endocrine and Metabolic Disease, National Hospital Organization Kyoto Medical Center, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoko","family":"Saiga","sequence":"additional","affiliation":[{"name":"Division of Health Administration and Promotion, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan; Department of Preventive Medicine, Clinical Research Institute for Endocrine and Metabolic Disease, National Hospital\r Organization Kyoto Medical Center, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kokoro","family":"Tsuzaki","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Clinical Research Institute for Endocrine and Metabolic Disease, National Hospital Organization Kyoto Medical Center, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiko","family":"Sano","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Clinical Research Institute for Endocrine and Metabolic Disease, National Hospital Organization Kyoto Medical Center, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haosheng","family":"Mu","sequence":"additional","affiliation":[{"name":"Division of Health Administration and Promotion, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youichi","family":"Kurozawa","sequence":"additional","affiliation":[{"name":"Division of Health Administration and Promotion, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2007,1,1]]},"container-title":["Annals of Clinical Biochemistry: International Journal of Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/000456307779595959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/000456307779595959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:54:26Z","timestamp":1777377266000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/000456307779595959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1,1]]}},"alternative-id":["10.1258\/000456307779595959"],"URL":"https:\/\/doi.org\/10.1258\/000456307779595959","relation":{},"ISSN":["0004-5632","1758-1001"],"issn-type":[{"value":"0004-5632","type":"print"},{"value":"1758-1001","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1,1]]}}}