{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:51:53Z","timestamp":1777434713277,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Biochem"],"published-print":{"date-parts":[[2007,3,1]]},"abstract":"<jats:p>A 26-year-old female overseas student was admitted to hospital with a fracture of her left humerus following minimal trauma. Biochemical abnormalities included hypercalcaemia, hypophosphataemia, raised alkaline phosphatase, raised parathyroid hormone and undetectable 25-hydroxy-vitamin D. Skeletal X-rays revealed multiple osteolytic lesions in the humerus as well as similar lesions in the femora and pelvis. Magnetic resonance imaging of her left shoulder showed a large soft tissue mass in the proximal humerus. Bone biopsy was reported as consistent with a brown tumour of primary hyperparathyroidism and a sestamibi scan confirmed the presence of a parathyroid adenoma. However, the isotope bone scan was reported as showing features typical of fibrous dysplasia involving multiple sites. The patient subsequently fractured her right femoral shaft, and a femoral nail was inserted. Parathyroidectomy was performed at the same time. Postoperatively she exhibited increased calcium and vitamin D requirements. Coexistence of primary hyperparathyroidism and polyostotic fibrous dysplasia is very rare.<\/jats:p>","DOI":"10.1258\/000456307780118145","type":"journal-article","created":{"date-parts":[[2007,3,13]],"date-time":"2007-03-13T19:43:02Z","timestamp":1173814982000},"page":"192-195","source":"Crossref","is-referenced-by-count":1,"title":["A rare case of metabolic bone disease"],"prefix":"10.1177","volume":"44","author":[{"given":"Rajeev","family":"Srivastava","sequence":"first","affiliation":[{"name":"Department of Biochemical Medicine, Ninewells Hospital & Medical School, Dundee DD1 9SY, Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona","family":"Jenkinson","sequence":"additional","affiliation":[{"name":"Department of Biochemical Medicine, Ninewells Hospital & Medical School, Dundee DD1 9SY, Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Biochemical Medicine, Ninewells Hospital & Medical School, Dundee DD1 9SY, Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2007,3,1]]},"container-title":["Annals of Clinical Biochemistry: International Journal of Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/000456307780118145","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/000456307780118145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:54:36Z","timestamp":1777377276000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/000456307780118145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3,1]]}},"alternative-id":["10.1258\/000456307780118145"],"URL":"https:\/\/doi.org\/10.1258\/000456307780118145","relation":{},"ISSN":["0004-5632","1758-1001"],"issn-type":[{"value":"0004-5632","type":"print"},{"value":"1758-1001","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,1]]}}}