{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:52:03Z","timestamp":1777434723165,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Biochem"],"published-print":{"date-parts":[[2007,7,1]]},"abstract":"<jats:p>We report on two teenage girls presenting following significant paracetamol overdoses (&gt;28 g paracetamol). Both presented within 4 h of the overdose and both were treated with N-acetylcysteine, in accordance with the National Poisons Information Service protocol. Within 8 h of presentation both had developed significant hypokalaemia with serum potassium concentrations &lt;3.0 mmol\/L and were treated with intravenous potassium chloride. Potassium concentrations returned to within reference limits (&gt;3.5 mmol\/L) after commencing potassium chloride supplementation. An audit of potassium concentrations in 254 patients presenting with significant paracetamol overdose (paracetamol &gt;0.5 mmol\/L) admitted through four A&amp;E departments in the West of Scotland showed a significant decline in mean serum potassium from 3.9 mmol\/L on admission to 3.6 mmol\/L ( P = &lt;0.001) over the next 36 h. The mechanism for this hypokalaemia in these two individuals is unclear, however regular monitoring of potassium is advocated in such patients during their initial treatment.<\/jats:p>","DOI":"10.1258\/000456307780945615","type":"journal-article","created":{"date-parts":[[2007,6,16]],"date-time":"2007-06-16T13:38:09Z","timestamp":1182001089000},"page":"403-405","source":"Crossref","is-referenced-by-count":5,"title":["Hypokalaemia following paracetamol overdose in two teenage girls"],"prefix":"10.1177","volume":"44","author":[{"given":"Ian M","family":"Godber","sequence":"first","affiliation":[{"name":"Biochemistry Department, Wishaw General Hospital, Wishaw, Lanarkshire, ML2 0DP, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J","family":"Jarvis","sequence":"additional","affiliation":[{"name":"Biochemistry Department, Glasgow Royal Infirmary, Glasgow, G4 0SF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donogh","family":"Maguire","sequence":"additional","affiliation":[{"name":"Accident and Emergency Wishaw General Hospital, Wishaw, Lanarkshire, ML2 0DP, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2007,7,1]]},"container-title":["Annals of Clinical Biochemistry: International Journal of Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/000456307780945615","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/000456307780945615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:54:40Z","timestamp":1777377280000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/000456307780945615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,7,1]]}},"alternative-id":["10.1258\/000456307780945615"],"URL":"https:\/\/doi.org\/10.1258\/000456307780945615","relation":{},"ISSN":["0004-5632","1758-1001"],"issn-type":[{"value":"0004-5632","type":"print"},{"value":"1758-1001","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7,1]]}}}