{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:10:25Z","timestamp":1790982625491,"version":"4.1.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2006,3,8]],"date-time":"2006-03-08T00:00:00Z","timestamp":1141776000000},"content-version":"unspecified","delay-in-days":1011,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2003,6]]},"abstract":"<jats:p>The aetiopathogenesis of acute unilateral peripheral vestibular dysfunction (APV), also known as vestibular neuritis, is still debated: the principal cause is viral infection with vascular factors second in importance.<\/jats:p><jats:p>Plasmatic D-dimer, considered a plasmatic index of hypercoagulation, was measured in a group of 45 APV patients and in a group of 25 patients suffering from M\u00e9ni\u00e8re\u2019s disease. Measurements were taken both during the acute stage and after a four to six week period of pharmacological washout. The mean D-dimer levels were significantly higher than those measured in the controls both during the acute phase (301 SD161 <jats:italic>vs<\/jats:italic> 202 SD113 ng\/mL) and after follow up (304 SD211 <jats:italic>vs<\/jats:italic> 192 SD111 ng\/mL) (<jats:italic>p<\/jats:italic> = 0.008). Moreover, during the acute stage 23 of the APV patients (51.1 per cent) had plasmatic D-dimer levels above the upper normal limit (i.e.: &lt;300 ng\/mL), compared to four of those with M\u00e9ni\u00e8re\u2019s disease (16 per cent).<\/jats:p><jats:p>Our results lead us to postulate\tan involvement of the haemostatic system in APV.<\/jats:p>","DOI":"10.1258\/002221503321892316","type":"journal-article","created":{"date-parts":[[2003,6,3]],"date-time":"2003-06-03T21:45:47Z","timestamp":1054676747000},"page":"467-472","source":"Crossref","is-referenced-by-count":11,"title":["Relevance of plasma D-dimer measurement in patients with acute peripheral vertigo"],"prefix":"10.1017","volume":"117","author":[{"given":"Bruno","family":"Fattori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Ursino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renza","family":"Cristofani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Galetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Nacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2006,3,8]]},"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221510300118X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T23:05:48Z","timestamp":1557183948000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221510300118X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["S002221510300118X"],"URL":"https:\/\/doi.org\/10.1258\/002221503321892316","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6]]}}}