{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T19:48:09Z","timestamp":1696362489876},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2006,5,31]],"date-time":"2006-05-31T00:00:00Z","timestamp":1149033600000},"content-version":"unspecified","delay-in-days":912,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2003,12]]},"abstract":"<jats:p>Most patients with squamous cancer of the head and neck treated at Groote Schuur Hospital are from a poor socio-economic background with a high prevalence of tuberculosis (TB), human immunodeficiency virus (HIV) and other infections that may cause cervical lymphadenopathy resulting in overstaging of the neck.<\/jats:p><jats:p>A retrospective review of 186 patients requiring therapeutic and elective neck dissection was undertaken and the sensitivity and specificity of clinical and intra-operative staging of the neck determined.<\/jats:p><jats:p>Results showed overall sensitivity of staging at 80.1 per cent. Specificity was 52.2 per cent. Staging of the N<jats:sub>1<\/jats:sub>, N<jats:sub>2b<\/jats:sub> and N<jats:sub>2c<\/jats:sub> necks had positive predictive values of 53.2, 65.8 and 68.2 per cent respectively. Occult nodal metastases were present in 32 per cent elective neck dissections (END)s. Specificity of intra-operative staging of the N<jats:sub>0<\/jats:sub> neck was 33.3 per cent and sensitivity was 72.4 per cent.<\/jats:p><jats:p>Conclusions were that our indications for elective neck dissection are appropriate. The high false positive rates for staging of the N<jats:sub>1<\/jats:sub>, N<jats:sub>2b<\/jats:sub> and N<jats:sub>2c<\/jats:sub> necks, necessitate a change in management strategy.<\/jats:p>","DOI":"10.1258\/002221503322683876","type":"journal-article","created":{"date-parts":[[2004,1,13]],"date-time":"2004-01-13T22:33:37Z","timestamp":1074033217000},"page":"976-978","source":"Crossref","is-referenced-by-count":7,"title":["Pre- and intra-operative staging of the neck in a developing world practice"],"prefix":"10.1017","volume":"117","author":[{"given":"Patrick J.","family":"de Waal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes J.","family":"Fagan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sedick","family":"Isaacs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2006,5,31]]},"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215103002500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T22:13:17Z","timestamp":1557180797000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215103002500\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,12]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2003,12]]}},"alternative-id":["S0022215103002500"],"URL":"https:\/\/doi.org\/10.1258\/002221503322683876","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,12]]}}}