{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:43:22Z","timestamp":1777884202726,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1980,1,1]],"date-time":"1980-01-01T00:00:00Z","timestamp":315532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lab Anim"],"published-print":{"date-parts":[[1980,1,1]]},"abstract":"<jats:p>This stock of albino mice is minimally inbred (0\u00b75% per generation), and has been rigidly selected for fecundity. It is widely employed in oncological and pharmaceutical research. Spontaneous tumours arose in 55% of animals, multiple in 28%, averaging 1\u00b766 per mouse. Females developed tumours at an earlier age than males. Predominant tumour types were pulmonary (23\u00b71%), lymphoreticular (20%), and mammary (14%-23% of females). Miscellaneous tumour types (42\u00b79%) ranged in frequency from 0\u00b72 to 2\u00b70%, the latter being hepatomas. Distribution of mammary tumours indicated that milk-borne mammary tumour virus was absent. Non-neoplastic disease was present in 58\u00b06%, 24\u00b01% being pulmonary and predominant in the young, while renal (31\u00b72%) and cardiovascular (10\u00b72%) disease was common in the elderly. Males outlived females.<\/jats:p>","DOI":"10.1258\/002367780780943141","type":"journal-article","created":{"date-parts":[[2007,6,16]],"date-time":"2007-06-16T13:38:09Z","timestamp":1182001089000},"page":"17-24","source":"Crossref","is-referenced-by-count":27,"title":["The Icr:Ha(ICR) mouse: a current account of breeding, mutations, diseases and mortality"],"prefix":"10.1177","volume":"14","author":[{"given":"Gordon J.","family":"Eaton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederic N.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Institute for Cancer Research, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, Pennsylvania 19111, United States of America"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Philip","family":"Custer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Reynolds","family":"Crane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1980,1,1]]},"container-title":["Laboratory Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/002367780780943141","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/002367780780943141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:16:27Z","timestamp":1777601787000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/002367780780943141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1980,1,1]]}},"alternative-id":["10.1258\/002367780780943141"],"URL":"https:\/\/doi.org\/10.1258\/002367780780943141","relation":{},"ISSN":["0023-6772","1758-1117"],"issn-type":[{"value":"0023-6772","type":"print"},{"value":"1758-1117","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,1,1]]}}}