{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:44:23Z","timestamp":1761155063653,"version":"3.33.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1985,10,1]],"date-time":"1985-10-01T00:00:00Z","timestamp":496972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lab Anim"],"published-print":{"date-parts":[[1985,10,1]]},"abstract":"<jats:p> Hysterectomy-derived germ-free rabbits were given colonization-resistant caecal flora (CRF) from mice, or microflora obtained from the caecum of an antibiotic-decontaminated conventional rabbit and compared with rabbits conventionally raised with the doe. Bodyweight and the following intestinal parameters were determined for the 3 groups: colonization resistance to E. coli, relative caecal weight, villus:crypt ratio (ileum), \u03b2-aspartylglycine (faeces), volatile fatty acids (caecum), and bile acids (faeces). Germ-free rabbits given mouse CRF-flora showed values quite different from control animals (or most parameters, indicating unsuitability of mouse CRF flora to 'normalize' rabbits. In germ-free rabbits given modified (antibiotic-treated) rabbit flora, values for most parameters were intermediate between those found for the other 2 groups. This species-specific caecal flora should be improved to provide full 'normalization' of germ-free rabbits. <\/jats:p>","DOI":"10.1258\/002367785780887428","type":"journal-article","created":{"date-parts":[[2007,6,6]],"date-time":"2007-06-06T23:37:28Z","timestamp":1181173048000},"page":"344-352","source":"Crossref","is-referenced-by-count":14,"title":["The 'normalization' of germ-free rabbits with host-specific caecal microflora"],"prefix":"10.1177","volume":"19","author":[{"given":"R.","family":"Boot","sequence":"first","affiliation":[{"name":"Department of Animal Supply, National Institute of Public Health and Environmental Hygiene, P.O. Box, 3720 BA Bitthoven, The Netherlands; Department for Laboratory Animal Bacteriology, National Institute of Public Health and Environmental Hygiene,\r P.O. Box, 3720 BA Bitthoven, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. P.","family":"Koopman","sequence":"additional","affiliation":[{"name":"Central Animal Laboratory, Catholic University, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. C.","family":"Kruijt","sequence":"additional","affiliation":[{"name":"Department of Animal Supply, National Institute of Public Health and Environmental Hygiene, P.O. Box, 3720 BA Bitthoven, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. M.","family":"Lammers","sequence":"additional","affiliation":[{"name":"Department for Laboratory Animal Bacteriology, National Institute of Public Health and Environmental Hygiene, P.O. Box, 3720 BA Bitthoven, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henri\u00ebtte M.","family":"Kennis","sequence":"additional","affiliation":[{"name":"Central Animal Laboratory, Catholic University, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Lankhorst","sequence":"additional","affiliation":[{"name":"Department for Laboratory Animal Science, Faculty of Veterinary Medicine, State University, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. W. M. A.","family":"Mullink","sequence":"additional","affiliation":[{"name":"Central Institute for the Breeding of Laboratory Animals TNO Zeist, Catholic University, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"Stadhouders","sequence":"additional","affiliation":[{"name":"Department of Submicroscopical Morphology, Catholic University, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"De Boer","sequence":"additional","affiliation":[{"name":"Department of Submicroscopical Morphology, Catholic University, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. W.","family":"Welling","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, State University Groningen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. P. C.","family":"Hectors","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Catholic University, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1985,10,1]]},"container-title":["Laboratory Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/002367785780887428","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/002367785780887428","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T03:55:45Z","timestamp":1738036545000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/002367785780887428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,10,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1985,10,1]]}},"alternative-id":["10.1258\/002367785780887428"],"URL":"https:\/\/doi.org\/10.1258\/002367785780887428","relation":{},"ISSN":["0023-6772","1758-1117"],"issn-type":[{"type":"print","value":"0023-6772"},{"type":"electronic","value":"1758-1117"}],"subject":[],"published":{"date-parts":[[1985,10,1]]}}}