{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T15:11:31Z","timestamp":1788361891817,"version":"build-2803163510"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1988,10,1]],"date-time":"1988-10-01T00:00:00Z","timestamp":591667200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lab Anim"],"published-print":{"date-parts":[[1988,10,1]]},"abstract":"<jats:p> The efficacy and safety of pentobarbitone, ketamine\/xylazine, fentanyl\/fluanisone\/diazepam, and halothane\/nitrous oxide anaesthesia were compared in 4 groups of six New Zealand White rabbits. Heart and respiratory rates, body temperature, reflexes, blood pressure and blood gases were measured. <\/jats:p><jats:p> Pentobarbitone appeared to be unsuitable for anaesthesia in rabbits, as 5 of the 6 rabbits to whom it was administered, required artificial respiration or died. The combinations of ketamine\/xylazine and fentanyl-f1uanisone\/diazepam both produced unpredictable levels of anaesthesia together with a substantial decline in arterial blood pressure and Po<jats:sub>2<\/jats:sub>. Despite a severe drop in blood pressure (up to 37\u00b75%), anaesthesia with halothane and nitrous oxide was found to be superior to the other anaesthetic agents. <\/jats:p>","DOI":"10.1258\/002367788780746197","type":"journal-article","created":{"date-parts":[[2007,5,20]],"date-time":"2007-05-20T23:45:00Z","timestamp":1179704700000},"page":"355-360","source":"Crossref","is-referenced-by-count":53,"title":["Four methods for general anaesthesia in the rabbit: a comparative study"],"prefix":"10.1177","volume":"22","author":[{"given":"M. E.","family":"Peeters","sequence":"first","affiliation":[{"name":"Small Animal Clinic, University of Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Gil","sequence":"additional","affiliation":[{"name":"Central Animal Laboratory, Academic Hospital Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Teske","sequence":"additional","affiliation":[{"name":"Small Animal Clinic, University of Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Eyzenbach","sequence":"additional","affiliation":[{"name":"Experimental Cardiology, Department of Cardiology, University of Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. E. v. d.","family":"Brom","sequence":"additional","affiliation":[{"name":"Small Animal Clinic, University of Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. T.","family":"Lumeij","sequence":"additional","affiliation":[{"name":"Small Animal Clinic, University of Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. W.","family":"de Vries","sequence":"additional","affiliation":[{"name":"Small Animal Clinic, University of Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1988,10,1]]},"container-title":["Laboratory Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/002367788780746197","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/002367788780746197","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T13:05:41Z","timestamp":1737723941000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/002367788780746197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,10,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1988,10,1]]}},"alternative-id":["10.1258\/002367788780746197"],"URL":"https:\/\/doi.org\/10.1258\/002367788780746197","relation":{},"ISSN":["0023-6772","1758-1117"],"issn-type":[{"value":"0023-6772","type":"print"},{"value":"1758-1117","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,10,1]]}}}