{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T05:23:21Z","timestamp":1741065801322,"version":"3.38.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1991,4,1]],"date-time":"1991-04-01T00:00:00Z","timestamp":670464000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lab Anim"],"published-print":{"date-parts":[[1991,4,1]]},"abstract":"<jats:p> The characteristics of HSV type-1 infection following subcutaneous inoculation in the dorsum of one hind paw of Sprague-Dawley rats were studied to determine whether infection in rats might more closely parallel the infection in man than is seen in other animals. The serologic and virologic characteristics of acute and latent ganglion infection conformed to those of human infection. Immunohistochemical studies suggested that sensory ganglion infection arose via centripetal axonal migration of virus as is hypothesized in man. In rat, small type B neuronal cell bodies appeared central to the maintenance of latent infection and reactivation observed during co-cultivation of lumbar ganglia. Acute and latent lumbar sensory ganglion infection in rats after subcutaneous hind paw injection of HSV-1 appears to be another suitable model of this infection in man. <\/jats:p>","DOI":"10.1258\/002367791781082568","type":"journal-article","created":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T23:45:04Z","timestamp":1183333504000},"page":"97-105","source":"Crossref","is-referenced-by-count":4,"title":["Characterization of acute and latent herpes simplex virus infection of dorsal root ganglia in rats"],"prefix":"10.1177","volume":"25","author":[{"given":"Joseph M.","family":"Blondeau","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada R3E OW3"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred Y.","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada R3E OW3; Departments of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada R3E OW3; Departments of Pharmacology and Therapeutics, University\r of Manitoba, Winnipeg, Manitoba, Canada R3E OW3"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary B.","family":"Glavin","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, Manitoba, Canada R3E OW3; Departments of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada R3E OW3"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James I.","family":"Nagy","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Manitoba, Winnipeg, Manitoba, Canada R3E OW3"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1991,4,1]]},"container-title":["Laboratory Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/002367791781082568","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/002367791781082568","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T06:47:36Z","timestamp":1740984456000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/002367791781082568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,4,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,4,1]]}},"alternative-id":["10.1258\/002367791781082568"],"URL":"https:\/\/doi.org\/10.1258\/002367791781082568","relation":{},"ISSN":["0023-6772","1758-1117"],"issn-type":[{"type":"print","value":"0023-6772"},{"type":"electronic","value":"1758-1117"}],"subject":[],"published":{"date-parts":[[1991,4,1]]}}}