{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T09:10:12Z","timestamp":1774861812707,"version":"3.50.1"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2006,10,1]]},"abstract":"<jats:p> Multi-organ involvement by opportunistic infections and neoplasms is the major cause of morbidity and mortality in people living with HIV\/AIDS. We determined the spectrum\/frequency of hepatic histopathological lesions in a prospective study of postmortem liver biopsies from 100 patients (50 females and 50 males, age range 18-55 years) who died from HIV\/AIDS in Jos university teaching hospital, Nigeria. The majority of the patients, 65 (65%), had clinical tuberculosis. Granulomatous hepatitis, chronic hepatitis, non-specific reactive hepatitis (NSRH) and steatosis were the commonest hepatic histopathologic lesions occurring in 34, 20,15 and 12% of patients, respectively. Seven (7%) had normal histological features. This study shows that the liver is affected in HIV\/AIDS as reported elsewhere in the world. Therefore, liver biopsy in HIV patients may be helpful in the management of these patients. <\/jats:p>","DOI":"10.1258\/004947506778604832","type":"journal-article","created":{"date-parts":[[2006,10,8]],"date-time":"2006-10-08T23:11:12Z","timestamp":1160349072000},"page":"228-231","source":"Crossref","is-referenced-by-count":9,"title":["Hepatic histopathological findings in HIV patients at postmortem in Jos university teaching hospital, Nigeria"],"prefix":"10.1177","volume":"36","author":[{"given":"Godwins O","family":"Echejoh","sequence":"first","affiliation":[{"name":"Department of Anatomic Pathology;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barnabas M","family":"Mandong","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew N","family":"Tanko","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agabus N","family":"Manasseh","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edith N","family":"Okeke","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Jos University Teaching Hospital, Jos, Plateau state, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel I","family":"Agaba","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Jos University Teaching Hospital, Jos, Plateau state, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,10,1]]},"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/004947506778604832","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/004947506778604832","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T02:37:10Z","timestamp":1740969430000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/004947506778604832"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,10,1]]}},"alternative-id":["10.1258\/004947506778604832"],"URL":"https:\/\/doi.org\/10.1258\/004947506778604832","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,1]]}}}