{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T17:58:20Z","timestamp":1775152700128,"version":"3.50.1"},"reference-count":0,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2000,12,1]],"date-time":"2000-12-01T00:00:00Z","timestamp":975628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2000,12,1]]},"abstract":"<jats:p> Our objectives were to describe the baseline findings of a trial of antibiotic prophylaxis to prevent sexually transmitted infections (STIs) and HIV-1 in a cohort of Nairobi female sex workers (FSWs). A questionnaire was administered and a medical examination was performed. HIV-negative women were randomly assigned to either one gram azithromycin or placebo monthly. Mean age of the 318 women was 32 years, mean duration of sex work 7 years and mean number of clients was 4 per day. High-risk behaviour was frequent: 14% practised anal intercourse, 23% sex during menses, and 3% used intravenous drugs. While 20% reported condom use with all clients, 37% never use condoms. However, STI prevalence was relatively low: HIV-1 27%, bacterial vaginosis 46%, Trichomonas vaginalis 13%, Neisseria gonorrhoeae 8%, Chlamydia trachomatis 7%, syphilis 6% and cervical intraepithelial neoplasia (CIN) 3%. It appears feasible to access a population of high-risk FSWs in Nairobi with prevention programmes, including a proposed trial of HIV prevention through STI chemoprophylaxis. <\/jats:p>","DOI":"10.1258\/0956462001915327","type":"journal-article","created":{"date-parts":[[2002,10,16]],"date-time":"2002-10-16T09:48:30Z","timestamp":1034761710000},"page":"804-811","source":"Crossref","is-referenced-by-count":33,"title":["A randomized, placebo-controlled trial of monthly azithromycin                prophylaxis to prevent sexually transmitted infections and HIV-1 in Kenyan sex                workers: study design and baseline findings"],"prefix":"10.1177","volume":"11","author":[{"given":"K","family":"Fonck","sequence":"first","affiliation":[{"name":"International Center for Reproductive Health, Department of Obstetrics\r                  and Gynaecology, Ghent University, Belgium and Departments of Medical Microbiology\r                  and Community Health, University of Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Kaul","sequence":"additional","affiliation":[{"name":"Departments of Medical Microbiology and Community Health, University\r                  of Nairobi, Kenya and Departments of Medical Microbiology, Community Health\r                  Sciences and Medicine, University of Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Kimani","sequence":"additional","affiliation":[{"name":"Departments of Medical Microbiology and Community Health, University\r                  of Nairobi, Kenya and Departments of Medical Microbiology, Community Health\r                  Sciences and Medicine, University of Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Keli","sequence":"additional","affiliation":[{"name":"Departments of Medical Microbiology and Community Health, University\r                  of Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K S","family":"MacDonald","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Mount Sinai Hospital, Toronto & Department of Medicine, University of Toronto, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A R","family":"Ronald","sequence":"additional","affiliation":[{"name":"Departments of Medical Microbiology, Community Health Sciences and\r                  Medicine, University of Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F A","family":"Plummer","sequence":"additional","affiliation":[{"name":"Departments of Medical Microbiology and Community Health, University\r                  of Nairobi, Kenya and Departments of Medical Microbiology, Community Health\r                  Sciences and Medicine, University of Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Kirui","sequence":"additional","affiliation":[{"name":"Department of Public Health, Nairobi City Council, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J J","family":"Bwayo","sequence":"additional","affiliation":[{"name":"Departments of Medical Microbiology and Community Health, University\r                  of Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E N","family":"Ngugi","sequence":"additional","affiliation":[{"name":"Departments of Medical Microbiology and Community Health, University\r                  of Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Moses","sequence":"additional","affiliation":[{"name":"Departments of Medical Microbiology, Community Health Sciences and\r                  Medicine, University of Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Temmerman","sequence":"additional","affiliation":[{"name":"International Center for Reproductive Health, Department of\r                  Obstetrics and Gynaecology, Ghent University, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,12,1]]},"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/0956462001915327","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/0956462001915327","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T07:16:26Z","timestamp":1740813386000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/0956462001915327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,12,1]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2000,12,1]]}},"alternative-id":["10.1258\/0956462001915327"],"URL":"https:\/\/doi.org\/10.1258\/0956462001915327","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,12,1]]}}}