{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T05:41:25Z","timestamp":1740807685397,"version":"3.38.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2004,4,1]]},"abstract":"<jats:p> This paper describes the efficacy of azithromycin 1g single dose in the management of uncomplicated gonorrhoea either with or without chlamydial co-infection. Three hundred and one patients were treated for gonorrhoea between January 2000 and June 2001; 226\/301 (75.1%) were treated with azithromycin 1g stat dose while the rest were treated with different regimens. Ninety-seven of 301 (32.2%) of all isolated strains were found to be resistant to at least one antibiotic where penicillin constituted the majority (23%). Chlamydial co-infection was found in 38.2% (115\/301). Only 73.1% (220\/301) attended for a test-of-cure, all but six patients had negative gonorrhoea cultures at their reviews. Among the six failures 3\/32 (9.3%) were initially on amoxicillin, 2\/170 (1.2%) on azithromycin and 1\/22 (4.5%) on ciprofloxacin. Hence, azithromycin stat dose has proved to be a cost-effective treatment for uncomplicated gonorrhoea supported by the increased prevalence of penicillin-resistant organisms, concomitant chlamydial infection and the high failure rate in keeping review appointments. <\/jats:p>","DOI":"10.1258\/095646204773557767","type":"journal-article","created":{"date-parts":[[2004,4,10]],"date-time":"2004-04-10T02:34:19Z","timestamp":1081564459000},"page":"240-242","source":"Crossref","is-referenced-by-count":13,"title":["Efficacy of azithromycin 1g single dose in the management of uncomplicated gonorrhoea"],"prefix":"10.1177","volume":"15","author":[{"given":"Amgad R","family":"Habib","sequence":"first","affiliation":[{"name":"Department of Genitourinary Medicine, New Cross Hospital, Wednesfield Road, Wolverhampton WV10 0QP, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rufus","family":"Fernando","sequence":"additional","affiliation":[{"name":"Department of Genitourinary Medicine, New Cross Hospital, Wednesfield Road, Wolverhampton WV10 0QP, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,4,1]]},"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/095646204773557767","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/095646204773557767","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T16:35:47Z","timestamp":1740760547000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/095646204773557767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,4,1]]}},"alternative-id":["10.1258\/095646204773557767"],"URL":"https:\/\/doi.org\/10.1258\/095646204773557767","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"type":"print","value":"0956-4624"},{"type":"electronic","value":"1758-1052"}],"subject":[],"published":{"date-parts":[[2004,4,1]]}}}