{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:21:48Z","timestamp":1761578508972,"version":"3.38.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2005,4,1]]},"abstract":"<jats:p> AIDS wasting syndrome results in loss of lean body mass and body cell mass. This 12-week, open-label study used bioelectrical impedance analysis to measure body composition changes in 24 patients with AIDS wasting syndrome receiving recombinant human growth hormone (r-hGH). The primary endpoint was percentage monthly change in body weight before\/after r-hGH. Secondary endpoints included change from baseline in body composition (bioelectrical impedance analysis), isometric strength and CD4+count. Twenty patients completed the study: r-hGH resulted in mean weight gains (+2.7%, P=0.146), and significant increases in mean body cell mass (+8.0%, P=0.0211), lean body mass (+4.8%, P=0.0373) and water (+5.5%, P&lt;0.023). Body fat decreased throughout, but not significantly. r-hGH was generally well tolerated; the most frequent adverse events were fever (7.3%) and diarrhoea (6.3%). Thus, bioelectrical impedance analysis can detect improved body cell mass independent of changes in body weight resulting from r-hGH treatment in patients with AIDS wasting syndrome. <\/jats:p>","DOI":"10.1258\/0956462053654177","type":"journal-article","created":{"date-parts":[[2005,4,21]],"date-time":"2005-04-21T06:28:44Z","timestamp":1114064924000},"page":"307-313","source":"Crossref","is-referenced-by-count":4,"title":["Use of bioelectrical impedance analysis to determine body composition changes in HIV-associated wasting"],"prefix":"10.1177","volume":"16","author":[{"given":"Stephan","family":"Klauke","sequence":"first","affiliation":[{"name":"HIV-Schwerpunktpraxis, Frankfurt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harald","family":"Fischer","sequence":"additional","affiliation":[{"name":"Internistische Praxis, Frankfurt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Rieger","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Dermatologie, AHK Wien, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Fr\u00fchauf","sequence":"additional","affiliation":[{"name":"Internistische Praxis, Offenbach, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Schlomo","family":"Staszewski","sequence":"additional","affiliation":[{"name":"Medizinische Klinik III (Schwerpunkt Infektiologie) Johann Wolfgang Goethe Universit\u00e4t, Frankfurt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter-Henning","family":"Althoff","sequence":"additional","affiliation":[{"name":"Medizinische Klinik B\u00fcrgerhospital, Frankfurt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eilke Brigitte","family":"Helm","sequence":"additional","affiliation":[{"name":"Medizinische Klinik III (Schwerpunkt Infektiologie) Johann Wolfgang Goethe Universit\u00e4t, Frankfurt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2005,4,1]]},"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/0956462053654177","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/0956462053654177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T16:40:25Z","timestamp":1740847225000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/0956462053654177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,4,1]]}},"alternative-id":["10.1258\/0956462053654177"],"URL":"https:\/\/doi.org\/10.1258\/0956462053654177","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"type":"print","value":"0956-4624"},{"type":"electronic","value":"1758-1052"}],"subject":[],"published":{"date-parts":[[2005,4,1]]}}}