{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T10:32:39Z","timestamp":1767177159643,"version":"build-2238731810"},"reference-count":0,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2005,5,1]]},"abstract":"<jats:p>New diagnoses of syphilis in the UK increased eight-fold between 1997 and 2002. This study, conducted in 2002, demonstrated that 31% of clinics were not confident of their expertise to obtain an adequate specimen for dark ground microscopy (DGM), and 35% were not confident of their expertise to detect treponemes on DGM. In all, 64% of clinics had observed adherence problems in HIV-positive patients treated with parenteral regimens, as against 42% with oral regimens. Also, 51% of clinics waited more than a week for the results of initial serological tests for syphilis, and 88% of clinics waited more than a week for confirmatory test results. Other concerns include the failure to perform syphilis serology consistently whenever HIV-positive patients were at risk, and the widespread use of doxycycline as a therapy for syphilis in HIV-positive patients despite concerns that this is not known to be fully treponemicidal in cerebrospinal fluid.<\/jats:p>","DOI":"10.1258\/0956462053888899","type":"journal-article","created":{"date-parts":[[2005,5,17]],"date-time":"2005-05-17T14:57:31Z","timestamp":1116341851000},"page":"348-352","source":"Crossref","is-referenced-by-count":8,"title":["Screening, diagnosis and management of early syphilis in genitourinary medicine clinics in the UK"],"prefix":"10.1177","volume":"16","author":[{"given":"K E","family":"Rogstad","sequence":"first","affiliation":[{"name":"Royal Hallamshire Hospital, Sheffield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Simms","sequence":"additional","affiliation":[{"name":"Health Protection Agency, Communicable Disease Surveillance Centre, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K A","family":"Fenton","sequence":"additional","affiliation":[{"name":"Health Protection Agency, Communicable Disease Surveillance Centre, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Edwards","sequence":"additional","affiliation":[{"name":"West Suffolk Hospital, Bury St Edmunds, Suffolk, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Fisher","sequence":"additional","affiliation":[{"name":"Brighton Health Care Trust, Brighton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C A","family":"Carne","sequence":"additional","affiliation":[{"name":"Clinic 1A, Box 38, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2005,5,1]]},"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/0956462053888899","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/0956462053888899","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T09:52:57Z","timestamp":1740822777000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/0956462053888899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5,1]]},"references-count":0,"aliases":["10.1258\/0956462053888916","10.1258\/0956462054063965"],"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,5,1]]}},"alternative-id":["10.1258\/0956462053888899"],"URL":"https:\/\/doi.org\/10.1258\/0956462053888899","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,5,1]]}}}