{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T13:05:06Z","timestamp":1789909506614,"version":"4.0.1"},"reference-count":0,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2006,7,1]]},"abstract":"<jats:p> Our objective was to determine the optimal duration of treatment with imiquimod for external genital warts over 4, 8, 12 or 16 weeks. A total of 120 women with a history of genital warts for a median of 3\u20136 months and prior alternative treatments in 73% were evaluated for total clearance rates. There was no statistically significant difference in complete clearance rates after 16-week follow-up across treatment groups: four weeks (40.0%), eight weeks (48.4%), 12 weeks (39.3%) and 16 weeks (51.6%). Imiquimod was well tolerated, and in those treated for four weeks there was a lower incidence of local skin reactions such as erythema and erosion, and no incidences of pain. These preliminary results suggest that a four-week treatment course of imiquimod applied thrice weekly for women with external genital warts may provide a reasonable approach with comparable efficacy and compliance, and minimal adverse events, drug costs and clinic visits. <\/jats:p>","DOI":"10.1258\/095646206777689161","type":"journal-article","created":{"date-parts":[[2006,6,22]],"date-time":"2006-06-22T23:57:04Z","timestamp":1151020624000},"page":"448-452","source":"Crossref","is-referenced-by-count":33,"title":["An open-label phase II pilot study investigating the optimal duration of imiquimod 5% cream for the treatment of external genital warts in women"],"prefix":"10.1177","volume":"17","author":[{"given":"S M","family":"Garland","sequence":"first","affiliation":[{"name":"Department of Microbiology & Infectious Diseases, Royal Women's Hospital, Victoria, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Waddell","sequence":"additional","affiliation":[{"name":"STD Services, Clinic 275, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Mindel","sequence":"additional","affiliation":[{"name":"Sydney Sexual Health Centre, Sydney Hospital, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I M","family":"Denham","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre, Carlton, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"McCloskey","sequence":"additional","affiliation":[{"name":"Sexual Health Clinic, Royal Perth Hospital, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The Australian Genital Warts Study Group on Imiquimod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2006,7,1]]},"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/095646206777689161","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/095646206777689161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T09:16:01Z","timestamp":1740820561000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/095646206777689161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,1]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2006,7,1]]}},"alternative-id":["10.1258\/095646206777689161"],"URL":"https:\/\/doi.org\/10.1258\/095646206777689161","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7,1]]}}}