{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:54:48Z","timestamp":1777434888450,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Biochem"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:p>Antibody interference in immunoassays is an underestimated problem, which has the potential to cause patient harm and waste health-care resources. We report a case where thyroglobulin antibodies generated a false-positive thyroglobulin result delaying the diagnosis of thyrotoxicosis factitia masquerading as recurrent Graves' disease. A high index of clinical suspicion and good laboratory-clinician communication underpins effective clinical and laboratory strategies to detect potentially erroneous laboratory results due to endogenous antibody interference in immunoassays.<\/jats:p>","DOI":"10.1258\/acb.2007.007163","type":"journal-article","created":{"date-parts":[[2008,6,30]],"date-time":"2008-06-30T14:32:56Z","timestamp":1214836376000},"page":"325-327","source":"Crossref","is-referenced-by-count":16,"title":["Thyrotoxicosis factitia masquerading as recurrent Graves' disease: endogenous antibody immunoassay interference, a pitfall for the unwary"],"prefix":"10.1177","volume":"45","author":[{"given":"V R","family":"Jahagirdar","sequence":"first","affiliation":[{"name":"Department of Diabetes and Endocrinology"},{"name":"Department of Clinical Chemistry"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Strouhal","sequence":"additional","affiliation":[{"name":"Department of Radiology, New Cross Hospital, Wolverhampton WV10 0QP, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Holder","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, University Hospital Birmingham, Birmingham B29 6JB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Gama","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry"},{"name":"Research Institute, Wolverhampton University, West Midlands WY1 1SB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B M","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Endocrinology"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,5,1]]},"reference":[{"key":"bibr-ACB-07-163C1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2006.02439.x"},{"key":"bibr-ACB-07-163C2","doi-asserted-by":"publisher","DOI":"10.1258\/000456302760042128"},{"key":"bibr-ACB-07-163C3","doi-asserted-by":"publisher","DOI":"10.1373\/49.7.1163"},{"key":"bibr-ACB-07-163C4","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/44.3.440"},{"key":"bibr-ACB-07-163C5","doi-asserted-by":"publisher","DOI":"10.1177\/000456329903600603"},{"key":"bibr-ACB-07-163C6","first-page":"105","volume":"25","author":"Tate J","year":"2004","journal-title":"Clin Biochem Rev"},{"key":"bibr-ACB-07-163C7","doi-asserted-by":"publisher","DOI":"10.1007\/BF02938957"},{"key":"bibr-ACB-07-163C8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198208123070705"},{"key":"bibr-ACB-07-163C9","doi-asserted-by":"publisher","DOI":"10.1258\/0004563021902125"},{"key":"bibr-ACB-07-163C10","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0986"},{"key":"bibr-ACB-07-163C11","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-0671"},{"key":"bibr-ACB-07-163C12","unstructured":"Association for Clinical Biochemistry, British Thyroid Foundation.\n                      2006 UK Guidelines for the Use of Thyroid Function Tests\n                      . 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