{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:46:07Z","timestamp":1777477567052,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Left ventricular (LV) function is a vital parameter for prognosis, therapy guidance, and follow-up of cardiovascular disease. Dual-source computed tomography (DSCT) provides an accurate analysis of global LV function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To assess the performance of DSCT in the determination of global LV functional parameters in comparison with cardiovascular magnetic resonance (CMR) and two-dimensional transthoracic echocardiography (2D-TTE) in patients with valvular heart disease (VHD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>A total of 111 patients (58 men, mean age 49.9 years) with known VHD and who underwent DSCT, 2D-TTE, and CMR a period of 2 weeks before undergoing valve surgery were included in this study. LV end-systolic volume (ESV), end-diastolic volume (EDV), stroke volume (SV), and ejection fraction (EF) were calculated by DSCT using the threshold-based technique, by 2D-TTE using a modified Simpson's method, and by CMR using Simpson's method. Agreement for parameters of LV global function was determined with the Pearson's correlation coefficient ( r) and Bland-Altman analysis. All the DSCT and CMR data-sets were assessed independently by two readers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifty of the total 111 patients had aortic VHD, 29 patients had mitral VHD, and 32 patients had mixed aortic and mitral VHD. An excellent inter-observer agreement was seen for the assessment of global LV function using DSCT ( r = 0.910\u20130.983) and CMR ( r = 0.854\u20130.965). An excellent or good correlation ( r = 0.93, 0.95, 0.87, and 0.71, respectively, P &lt; 0.001) was noted between the DSCT and 2D-TTE values for EDV, ESV, SV, and EF. EDV (33.7 mL, P &lt; 0.001), ESV (12.1 mL, P &lt; 0.001), SV (21.2 mL, P &lt; 0.001), and EF (1.6%, P = 0.019) were significantly overestimated by DSCT when compared with 2D-TTE. An excellent correlation ( r = 0.96, 0.97, 0.91, and 0.94, respectively, P &lt; 0.001) between DSCT and CMR was seen in the evaluation of EDV, ESV, SV, and EF. EDV (15.9 mL, P &lt; 0.001), ESV (7.3 mL, P &lt; 0.001), and SV (8.5 mL, P &lt; 0.001) were significantly underestimated, but EF (1.1%, P = 0.002) was significantly overestimated by DSCT when compared with CMR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study showed that DSCT measurements of global LV function using the threshold-based technique were highly reproducible and compared more favorably with CMR measurements using Simpson's method than those of 2D-TTE using the modified Simpson's method. DSCT enables accurate quantification of global LV function in patients with VHD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1258\/ar.2011.110247","type":"journal-article","created":{"date-parts":[[2012,2,9]],"date-time":"2012-02-09T06:39:45Z","timestamp":1328769585000},"page":"270-277","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Assessment of global left ventricular function with dual-source computed tomography in patients with valvular heart disease"],"prefix":"10.1177","volume":"53","author":[{"given":"So Hyeon","family":"Bak","sequence":"first","affiliation":[{"name":"Department of Radiology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Min","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Radiology"},{"name":"Research Institute of Medical Science"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hae Jeong","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Radiology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Suk","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hweung Kon","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Cardiology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meong Gun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, 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