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Endometriosis is a polygenic disease with a complex, multifactorial etiology. The mechanism responsible for the initiation and development of this disease remains largely unknown. Prostaglandin E\n                    <jats:sub>2<\/jats:sub>\n                    (PGE\n                    <jats:sub>2<\/jats:sub>\n                    ), a versatile eicosanoid that exerts numerous physiological and pathological functions, has been implicated to play critical roles in the development of endometriosis. A growing body of evidence demonstrates that PGE\n                    <jats:sub>2<\/jats:sub>\n                    regulates many pathophysiological processes including cell proliferation, antiapoptosis, immune suppression and angiogenesis during the development of endometriosis. This review focuses on recent advances in cellular and molecular mechanisms triggered by PGE\n                    <jats:sub>2<\/jats:sub>\n                    that contribute to the pathological processes of endometriosis.\n                  <\/jats:p>","DOI":"10.1258\/ebm.2010.009321","type":"journal-article","created":{"date-parts":[[2010,5,28]],"date-time":"2010-05-28T12:59:36Z","timestamp":1275051576000},"page":"668-677","source":"Crossref","is-referenced-by-count":122,"title":["Prostaglandin E\n                    <sub>2<\/sub>\n                    : the master of endometriosis?"],"prefix":"10.3389","volume":"235","author":[{"given":"Meng-Hsing","family":"Wu","sequence":"first","affiliation":[{"name":"Departments of Obstetrics and Gynecology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Wun","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Physiology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan, 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