{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T05:43:35Z","timestamp":1777873415164,"version":"3.51.4"},"reference-count":109,"publisher":"Frontiers Media SA","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Biol Med (Maywood)"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:p>Prostate cancer is the leading cancer-related cause of death for men in the USA. Prostate cancer risk is significantly lower in Asian countries compared with the USA, which has prompted interest in the potential chemo-preventive action of soy and green tea that are more predominant in Asian diets. It has been proposed that chronic inflammation is a major risk factor of prostate cancer, acting as both an initiator and promoter. Specifically, the nuclear factor-kappa B (NF- \u03baB) pathway has been implicated as an important mediator between chronic inflammation, cell proliferation and prostate cancer. Dietary factors that inhibit inflammation and NF- \u03baB may serve as effective chemo-preventive agents. Recent studies have demonstrated that soy and green tea have anti-inflammatory properties, and may have the potential to block the inflammatory response during cancer progression. This minireview discusses the relationship between chronic inflammation and prostate cancer, emphasizing on the significance of NF- \u03baB, and further explores the anti-inflammatory effects of soy and green tea. Finally, we propose that dietary strategies that incorporate these bioactive food components as whole foods may be a more effective means to target pathways that contribute to prostate cancer development.<\/jats:p>","DOI":"10.1258\/ebm.2010.009335","type":"journal-article","created":{"date-parts":[[2010,5,28]],"date-time":"2010-05-28T12:59:36Z","timestamp":1275051576000},"page":"659-667","source":"Crossref","is-referenced-by-count":26,"title":["Anti-inflammatory activity of soy and tea in prostate cancer prevention"],"prefix":"10.3389","volume":"235","author":[{"given":"Anna","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Nutrition and Exercise Sciences, 103 Milam Hall"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tammy M","family":"Bray","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Exercise Sciences, 103 Milam Hall"},{"name":"Linus Pauling Institute, 571 Weniger Hall, Oregon State University, Corvallis, OR 97331, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Exercise Sciences, 103 Milam Hall"},{"name":"Linus Pauling Institute, 571 Weniger Hall, Oregon State University, Corvallis, OR 97331, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2010,6,1]]},"reference":[{"key":"bibr-EBM-0911-MR-335C1","doi-asserted-by":"publisher","DOI":"10.3322\/CA.2007.0010"},{"key":"bibr-EBM-0911-MR-335C2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)62086-X"},{"key":"bibr-EBM-0911-MR-335C3","doi-asserted-by":"publisher","DOI":"10.3109\/02841869109092336"},{"key":"bibr-EBM-0911-MR-335C4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.12.033"},{"key":"bibr-EBM-0911-MR-335C5","doi-asserted-by":"publisher","DOI":"10.1038\/nrc886"},{"key":"bibr-EBM-0911-MR-335C6","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgh317"},{"key":"bibr-EBM-0911-MR-335C7","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.12.011"},{"key":"bibr-EBM-0911-MR-335C8","doi-asserted-by":"publisher","DOI":"10.1002\/pros.10152"},{"key":"bibr-EBM-0911-MR-335C9","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0045(20000101)42:1<73::AID-PROS9>3.0.CO;2-G"},{"key":"bibr-EBM-0911-MR-335C10","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20000801)89:3<589::AID-CNCR14>3.0.CO;2-C"},{"key":"bibr-EBM-0911-MR-335C11","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-0732"},{"key":"bibr-EBM-0911-MR-335C12","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20331"},{"key":"bibr-EBM-0911-MR-335C13","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)61708-7"},{"key":"bibr-EBM-0911-MR-335C14","first-page":"362","volume":"58","author":"Sheng H","year":"1998","journal-title":"Cancer Res"},{"key":"bibr-EBM-0911-MR-335C15","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81433-6"},{"key":"bibr-EBM-0911-MR-335C16","first-page":"1208","volume":"58","author":"Huang M","year":"1998","journal-title":"Cancer Res"},{"key":"bibr-EBM-0911-MR-335C17","doi-asserted-by":"publisher","DOI":"10.1172\/JCI11891"},{"key":"bibr-EBM-0911-MR-335C18","doi-asserted-by":"publisher","DOI":"10.1172\/JCI11830"},{"key":"bibr-EBM-0911-MR-335C19","doi-asserted-by":"publisher","DOI":"10.1002\/mc.20217"},{"key":"bibr-EBM-0911-MR-335C20","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.10729"},{"key":"bibr-EBM-0911-MR-335C21","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.19.8.5785"},{"key":"bibr-EBM-0911-MR-335C22","first-page":"1275","volume":"21","author":"Li ZG","year":"2002","journal-title":"Int J Oncol"},{"key":"bibr-EBM-0911-MR-335C23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.45.32091"},{"key":"bibr-EBM-0911-MR-335C24","first-page":"2206","volume":"63","author":"Zerbini LF","year":"2003","journal-title":"Cancer Res"},{"key":"bibr-EBM-0911-MR-335C25","doi-asserted-by":"publisher","DOI":"10.1002\/pros.10082"},{"key":"bibr-EBM-0911-MR-335C26","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1204535"},{"key":"bibr-EBM-0911-MR-335C27","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(00)00218-5"},{"key":"bibr-EBM-0911-MR-335C28","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgl097"},{"key":"bibr-EBM-0911-MR-335C29","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2004.07.013"},{"key":"bibr-EBM-0911-MR-335C30","doi-asserted-by":"publisher","DOI":"10.1038\/nature02924"},{"key":"bibr-EBM-0911-MR-335C31","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.arplant.55.031903.141729"},{"key":"bibr-EBM-0911-MR-335C32","unstructured":"GilaniGS, AndersonJB. Phytoestrogens and Health. Champaign, IL: AOCS Press, 2002:660"},{"key":"bibr-EBM-0911-MR-335C33","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/71.6.1705S"},{"key":"bibr-EBM-0911-MR-335C34","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/9.2.101"},{"key":"bibr-EBM-0911-MR-335C35","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-217-44237"},{"key":"bibr-EBM-0911-MR-335C36","doi-asserted-by":"publisher","DOI":"10.1016\/0960-0760(93)90022-O"},{"key":"bibr-EBM-0911-MR-335C37","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/136.1.75"},{"key":"bibr-EBM-0911-MR-335C38","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)45614-1"},{"key":"bibr-EBM-0911-MR-335C39","first-page":"1061","volume":"19","author":"Schmidt F","year":"2008","journal-title":"Oncol Rep"},{"key":"bibr-EBM-0911-MR-335C40","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2000.tb00928.x"},{"key":"bibr-EBM-0911-MR-335C41","doi-asserted-by":"publisher","DOI":"10.1207\/S15327914NC330202"},{"key":"bibr-EBM-0911-MR-335C42","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4644(19980401)69:1<44::AID-JCB5>3.0.CO;2-V"},{"key":"bibr-EBM-0911-MR-335C43","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.200500154"},{"key":"bibr-EBM-0911-MR-335C44","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i8.1162"},{"key":"bibr-EBM-0911-MR-335C45","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2006.07.036"},{"key":"bibr-EBM-0911-MR-335C46","doi-asserted-by":"publisher","DOI":"10.1016\/0091-7435(92)90041-F"},{"key":"bibr-EBM-0911-MR-335C47","doi-asserted-by":"publisher","DOI":"10.1080\/10408399709527797"},{"key":"bibr-EBM-0911-MR-335C48","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008890529261"},{"key":"bibr-EBM-0911-MR-335C49","first-page":"307","volume":"402","author":"Fujiki H","year":"1998","journal-title":"MutatRes"},{"key":"bibr-EBM-0911-MR-335C50","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19970127)70:3<255::AID-IJC1>3.0.CO;2-W"},{"key":"bibr-EBM-0911-MR-335C51","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1998.tb00556.x"},{"key":"bibr-EBM-0911-MR-335C52","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2003.06.001"},{"key":"bibr-EBM-0911-MR-335C53","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.24.883"},{"key":"bibr-EBM-0911-MR-335C54","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/21.10.1885"},{"key":"bibr-EBM-0911-MR-335C55","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.2000.1742"},{"key":"bibr-EBM-0911-MR-335C56","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2001.5415"},{"key":"bibr-EBM-0911-MR-335C57","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/133.11.3805S"},{"key":"bibr-EBM-0911-MR-335C58","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.171326098"},{"key":"bibr-EBM-0911-MR-335C59","doi-asserted-by":"publisher","DOI":"10.1126\/science.279.5350.563"},{"key":"bibr-EBM-0911-MR-335C60","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.18.1472"},{"key":"bibr-EBM-0911-MR-335C61","doi-asserted-by":"publisher","DOI":"10.1136\/mp.54.5.285"},{"key":"bibr-EBM-0911-MR-335C62","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3835(95)03948-V"},{"key":"bibr-EBM-0911-MR-335C63","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2007.09.001"},{"key":"bibr-EBM-0911-MR-335C64","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21266"},{"key":"bibr-EBM-0911-MR-335C65","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/131.10.3168"},{"key":"bibr-EBM-0911-MR-335C66","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-0517"},{"key":"bibr-EBM-0911-MR-335C67","doi-asserted-by":"publisher","DOI":"10.1079\/BJN20031075"},{"key":"bibr-EBM-0911-MR-335C68","doi-asserted-by":"publisher","DOI":"10.1081\/CNV-120023773"},{"key":"bibr-EBM-0911-MR-335C69","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1470295"},{"key":"bibr-EBM-0911-MR-335C70","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-7207(01)00663-3"},{"key":"bibr-EBM-0911-MR-335C71","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/137.7.1769"},{"key":"bibr-EBM-0911-MR-335C72","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.04.009"},{"key":"bibr-EBM-0911-MR-335C73","doi-asserted-by":"publisher","DOI":"10.1207\/S15327914NC3601_3"},{"key":"bibr-EBM-0911-MR-335C74","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.7.2690"},{"key":"bibr-EBM-0911-MR-335C75","doi-asserted-by":"crossref","first-page":"790S","DOI":"10.1093\/jn\/125.3_Suppl.790S","volume":"125","author":"Fotsis T","year":"1995","journal-title":"J Nutr"},{"key":"bibr-EBM-0911-MR-335C76","doi-asserted-by":"publisher","DOI":"10.1080\/01635589809514730"},{"key":"bibr-EBM-0911-MR-335C77","first-page":"1328","volume":"53","author":"Matsukawa Y","year":"1993","journal-title":"Cancer Res"},{"key":"bibr-EBM-0911-MR-335C78","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.01.004"},{"key":"bibr-EBM-0911-MR-335C79","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/136.3.704"},{"key":"bibr-EBM-0911-MR-335C80","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2008.10.020"},{"key":"bibr-EBM-0911-MR-335C81","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2008.00383.x"},{"key":"bibr-EBM-0911-MR-335C82","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05614.x"},{"key":"bibr-EBM-0911-MR-335C83","doi-asserted-by":"publisher","DOI":"10.1021\/jf802475z"},{"key":"bibr-EBM-0911-MR-335C84","first-page":"1389","volume":"25","author":"Valachovicova T","year":"2004","journal-title":"Int J Oncol"},{"key":"bibr-EBM-0911-MR-335C85","doi-asserted-by":"publisher","DOI":"10.1207\/S15327914NC352_11"},{"key":"bibr-EBM-0911-MR-335C86","first-page":"2369","volume":"8","author":"Li Y","year":"2002","journal-title":"Clin Cancer Res"},{"key":"bibr-EBM-0911-MR-335C87","first-page":"5178","volume":"62","author":"Christov KT","year":"2002","journal-title":"Cancer Res"},{"key":"bibr-EBM-0911-MR-335C88","first-page":"674","volume":"232","author":"Yatkin E","year":"2007","journal-title":"Exp Biol Med (Maywood)"},{"key":"bibr-EBM-0911-MR-335C89","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/80.13.1045"},{"key":"bibr-EBM-0911-MR-335C90","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1206583"},{"key":"bibr-EBM-0911-MR-335C91","doi-asserted-by":"publisher","DOI":"10.1038\/sj.pcan.4501000"},{"key":"bibr-EBM-0911-MR-335C92","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1207353"},{"key":"bibr-EBM-0911-MR-335C93","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgi040"},{"key":"bibr-EBM-0911-MR-335C94","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgi320"},{"key":"bibr-EBM-0911-MR-335C95","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgn161"},{"key":"bibr-EBM-0911-MR-335C96","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgh178"},{"key":"bibr-EBM-0911-MR-335C97","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/131.11.3095S"},{"key":"bibr-EBM-0911-MR-335C98","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/17.7.1451"},{"key":"bibr-EBM-0911-MR-335C99","doi-asserted-by":"publisher","DOI":"10.1021\/jf801981w"},{"key":"bibr-EBM-0911-MR-335C100","doi-asserted-by":"publisher","DOI":"10.1016\/S0027-5107(01)00181-6"},{"key":"bibr-EBM-0911-MR-335C101","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.12.3486S"},{"key":"bibr-EBM-0911-MR-335C102","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20380"},{"key":"bibr-EBM-0911-MR-335C103","doi-asserted-by":"publisher","DOI":"10.1258\/ebm.2009.009128"},{"key":"bibr-EBM-0911-MR-335C104","first-page":"1055","volume":"7","author":"Fournier DB","year":"1998","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"bibr-EBM-0911-MR-335C105","first-page":"263","volume":"4","author":"Kerwin SM","year":"2004","journal-title":"Curr Med Chem"},{"key":"bibr-EBM-0911-MR-335C106","doi-asserted-by":"publisher","DOI":"10.1080\/01635580701277478"},{"key":"bibr-EBM-0911-MR-335C107","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.11549"},{"key":"bibr-EBM-0911-MR-335C108","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/133.2.516"},{"key":"bibr-EBM-0911-MR-335C109","volume-title":"J Nutr Biochem","author":"Hsu A","year":"2010"}],"container-title":["Experimental Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/ebm.2010.009335","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/ebm.2010.009335","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/ebm.2010.009335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:55:59Z","timestamp":1777571759000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ebm-journal.org\/journals\/experimental-biology-and-medicine\/articles\/10.1258\/ebm.2010.009335\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":109,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1258\/ebm.2010.009335"],"URL":"https:\/\/doi.org\/10.1258\/ebm.2010.009335","relation":{},"ISSN":["1535-3702","1535-3699"],"issn-type":[{"value":"1535-3702","type":"print"},{"value":"1535-3699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}