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We present two cases of syphilitic hepatitis and performed a retrospective study to determine the incidence of hepatitis during early syphilis infections among HIV-infected persons. Our study showed that syphilitic hepatitis is common, occurring in 38% (12\/32) of HIV-positive patients with early stages of syphilis infection. Most cases occurred during secondary syphilis, with the most common finding being a maculopapular rash. Syphilis should be included in the differential diagnosis of HIV patients presenting with liver test abnormalities, rash and\/or sexual risk factors. <\/jats:p>","DOI":"10.1258\/ijsa.2008.008324","type":"journal-article","created":{"date-parts":[[2009,3,21]],"date-time":"2009-03-21T01:00:37Z","timestamp":1237597237000},"page":"278-284","source":"Crossref","is-referenced-by-count":54,"title":["Syphilitic hepatitis among HIV-infected patients"],"prefix":"10.1177","volume":"20","author":[{"given":"N","family":"Crum-Cianflone","sequence":"first","affiliation":[{"name":"HIV Clinic, Naval Medical Center San Diego, San Diego, CA"},{"name":"Infectious Diseases Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Weekes","sequence":"additional","affiliation":[{"name":"Infectious Diseases Clinical Research Program, Uniformed Services University of the Health Sciences, 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