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We measured the impact of the treatment of facial lipoatrophy with polymethyl methacrylate (PMMA) in the QOL of patients with HIV\/AIDS by using four questionnaires that address QOL. Forty consecutive patients on ART referred for facial lipoatrophy treatment were enrolled in this study. The first 20 were allocated to the intervention group and were treated with tissue augmentation with PMMA. The other 20 were allocated to the control group, which received treatment only after six months. At baseline, four questionnaires were applied to all patients in both groups and again after six months. The variation in scores within the control group for all domains of all four instruments was significantly better when compared with that within the control group. We detected improvement in the QOL of patients with HIV\/AIDS and facial lipoatrophy when they were treated with PMMA. <\/jats:p>","DOI":"10.1258\/ijsa.2009.009086","type":"journal-article","created":{"date-parts":[[2011,10,18]],"date-time":"2011-10-18T12:26:00Z","timestamp":1318940760000},"page":"596-599","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["The impact of facial lipoatrophy treatment with polymethyl methacrylate in AIDS patients as measured by four quality-of-life questionnaires"],"prefix":"10.1177","volume":"22","author":[{"given":"M","family":"Warde","sequence":"first","affiliation":[{"name":"Division of Plastic Surgery, Federal University of Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Gragnani","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Federal University of Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Gomes","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Federal University of Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Hochman","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Federal University of Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L M","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Federal University of Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,10,1]]},"reference":[{"key":"bibr-IJSA-09-086C1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200124030-00001"},{"key":"bibr-IJSA-09-086C2","first-page":"23","volume":"3","author":"Li HY","year":"2002","journal-title":"JBA"},{"key":"bibr-IJSA-09-086C3","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-005-5001-2"},{"key":"bibr-IJSA-09-086C4","doi-asserted-by":"publisher","DOI":"10.1310\/EYWJ-8B5K-X7VQ-9CPE"},{"key":"bibr-IJSA-09-086C5","doi-asserted-by":"publisher","DOI":"10.1097\/00126334-200212010-00006"},{"key":"bibr-IJSA-09-086C6","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2006.20.668"},{"key":"bibr-IJSA-09-086C7","doi-asserted-by":"publisher","DOI":"10.2310\/6350.2005.31237"},{"key":"bibr-IJSA-09-086C8","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-1298(20)30783-5"},{"key":"bibr-IJSA-09-086C9","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/103.4.466"},{"key":"bibr-IJSA-09-086C10","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199509000-00015"},{"key":"bibr-IJSA-09-086C11","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-822955"},{"key":"bibr-IJSA-09-086C12","first-page":"143","volume":"39","author":"Ciconelli RM","year":"1999","journal-title":"Rev Bras Rheumatol"},{"key":"bibr-IJSA-09-086C13","first-page":"41","volume":"19","author":"Dini GM","year":"2004","journal-title":"Rev Soc Bras Cir Plast S\u00e3o Paulo"},{"key":"bibr-IJSA-09-086C14","unstructured":"Di PietroMC. 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