{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T13:40:51Z","timestamp":1760708451376,"version":"3.38.0"},"reference-count":11,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p> This study evaluated a population with a relatively low prevalence of gonococcal (GC) infection attending a genitourinary (GU) medicine clinic. Nucleic acid amplification testing (NAAT) screening was compared with culture. A total of 2004 male urine, 1699 female endocervical and 424 self-taken vulvovaginal swabs were screened using the BD ProbeTec GC NAAT alongside Neisserial culture. ProbeTec-positive samples confirmed by the Gen-Probe Aptima GC NAAT and\/or culture positive were deemed to have GC infection. Thirty-three out of 4157 (0.8%) specimens gave a reactive result by BD ProbeTec NAAT. Twenty-two were confirmed by Gen-Probe Aptima NAAT alone (4), culture alone (7) or both (11). Four patients were identified with GC infection who would have been missed by standard culture. No samples were culture positive and ProbeTec NAAT negative. Of 11 unconfirmed reactive samples, five gave low readings and three were contacts of gonorrhoea. Screening for Neisseria gonorrhoeae using NAAT is a viable alternative to culture even in a low-prevalence population. <\/jats:p>","DOI":"10.1258\/ijsa.2009.009527","type":"journal-article","created":{"date-parts":[[2012,7,17]],"date-time":"2012-07-17T15:58:14Z","timestamp":1342540694000},"page":"e1-e3","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Screening for <i>Neisseria gonorrhoeae<\/i> using the BD ProbeTec nucleic acid amplification test in a low prevalence genitourinary medicine clinic"],"prefix":"10.1177","volume":"23","author":[{"given":"V","family":"Killick","sequence":"first","affiliation":[{"name":"Department of Genitourinary Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Kell","sequence":"additional","affiliation":[{"name":"Department of Genitourinary Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Plumb","sequence":"additional","affiliation":[{"name":"Microbiology, Torbay Hospital, Lawes Bridge, Torquay, Devon TQ2 7AA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Hurd","sequence":"additional","affiliation":[{"name":"Microbiology, Torbay Hospital, Lawes Bridge, Torquay, Devon TQ2 7AA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Turner","sequence":"additional","affiliation":[{"name":"Microbiology, Torbay Hospital, Lawes Bridge, Torquay, Devon TQ2 7AA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,6,1]]},"reference":[{"key":"bibr-IJSA-09-527C1","unstructured":"Health Protection Agency. All New STI Episodes Seen at GUM Clinics in the UK: 1998\u20132007. See www.hpa.org.uk (last accessed 22 July 2011)"},{"key":"bibr-IJSA-09-527C2","unstructured":"Health Protection Agency. Sexually Transmitted Infections and Young People in the United Kingdom: 2008 Report. See www.hpa.org.uk (last accessed 22 July 2011)"},{"key":"bibr-IJSA-09-527C3","first-page":"6","volume":"83","author":"Ross J","year":"2006","journal-title":"Sex Transm Infect"},{"key":"bibr-IJSA-09-527C4","unstructured":"Department of Health. Better Prevention Better Services Better Sexual Health: The National Strategy for Sexual Health and HIV. London: Department of Health, 2001. See http:\/\/www.dh.gov.uk (last accessed 22 July 2011)"},{"key":"bibr-IJSA-09-527C5","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2005.017616"},{"key":"bibr-IJSA-09-527C6","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2006.022731"},{"key":"bibr-IJSA-09-527C7","unstructured":"South West Regional Sexual Health Task Group. Regional Guidance on the Use of Gonococcal Nucleic Acid Amplification Tests (GC NAATs) in Clinical Practice. South West Regional Sexual Health Task Group Advisory Note 4, February 2009. See http:\/\/www.hpa.org.uk (last accessed 22 July 2011)"},{"key":"bibr-IJSA-09-527C8","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2006.021816"},{"key":"bibr-IJSA-09-527C9","doi-asserted-by":"publisher","DOI":"10.1258\/095646207781439784"},{"key":"bibr-IJSA-09-527C10","unstructured":"DaveJ, EastawayA. Guidance on the Introduction of Molecular Testing for Neisseria gonorrhoeae in Diagnostic Laboratories. Health Protection Scotland, 2007. See http:\/\/www.hps.scot.nhs.uk (last accessed 22 July 2011)"},{"key":"bibr-IJSA-09-527C11","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2008.032789"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/ijsa.2009.009527","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/ijsa.2009.009527","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/ijsa.2009.009527","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T05:54:28Z","timestamp":1740981268000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/ijsa.2009.009527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1258\/ijsa.2009.009527"],"URL":"https:\/\/doi.org\/10.1258\/ijsa.2009.009527","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"type":"print","value":"0956-4624"},{"type":"electronic","value":"1758-1052"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}