{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T18:33:24Z","timestamp":1774118004532,"version":"3.50.1"},"reference-count":34,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:p> A prognostic scoring tool (PST) was created to aid prediction of outcome from HIV-associated Pneumocystis jirovecii pneumonia (PCP) using data obtained from 577 episodes of PCP among 540 patients presenting to a specialist HIV treatment centre in London, UK. It used risk factors identifiable at\/soon after hospitalization, previously identified as being associated with mortality: repeat episode of PCP, patient's age, haemoglobin (Hb) and oxygen partial pressure (PaO2) on admission, presence of medical co-morbidity (Comorb) and of pulmonary Kaposi sarcoma (PKS). The derived PST was 25.5+(age in years\/10) + 2 (if a repeat episode of PCP) + 3 (if Comorb present) + 4 (if PKS detected) \u2013 PaO2 (kPa) \u2013 Hb (g\/dL), and produced scores that ranged between 0 and 19. Patients were divided into five groups according to their prognostic score: 0-3.9 = group 1 (0% mortality), 4-7.9 = group 2 (3% mortality), 8-10.9 = group 3 (9% mortality), 11-14.9 = group 4 (29% mortality) and \u226515 = group 5 (52% mortality). This PST facilitates rapid identification of patients early in their hospitalization who have mild or severe HIV-associated PCP and who are at high and low risk of in-hospital death from PCP. The PST may aid assessment of severity of illness and in directing treatment strategies, but requires validation in patient cohorts from other healthcare institutions. <\/jats:p>","DOI":"10.1258\/ijsa.2011.011040","type":"journal-article","created":{"date-parts":[[2011,11,17]],"date-time":"2011-11-17T18:36:42Z","timestamp":1321555002000},"page":"628-634","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["A prognostic scoring tool for identification of patients at high and low risk of death from HIV-associated Pneumocystis jirovecii pneumonia"],"prefix":"10.1177","volume":"22","author":[{"given":"D","family":"Armstrong-James","sequence":"first","affiliation":[{"name":"Section of Infectious Diseases and Immunity, Imperial College London"},{"name":"Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A J","family":"Copas","sequence":"additional","affiliation":[{"name":"Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, Division of Population Health, University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P D","family":"Walzer","sequence":"additional","affiliation":[{"name":"Research Service, Veterans Affairs Medical Center"},{"name":"Division of Infectious Diseases. 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