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Although benzathine penicillin G cannot achieve treponemicidal levels in the CSF, decreased rates of neurological complications of syphilis and non-treponemal titre serological responses are usually observed after treatment with this antibiotic. We here a homosexual man with ANS successfully treated with benzathine penicillin G. This case suggests that reconsideration on the necessity of a lumbar puncture in HIV-infected patients with ANS is warranted. <\/jats:p>","DOI":"10.1258\/ijsa.2012.012124","type":"journal-article","created":{"date-parts":[[2012,10,25]],"date-time":"2012-10-25T15:21:48Z","timestamp":1351178508000},"page":"756-757","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Optimal treatment for asymptomatic neurosyphilis"],"prefix":"10.1177","volume":"23","author":[{"given":"H C","family":"Tsai","sequence":"first","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan and National Yang-Ming University, 386 Ta-Chung 1st Road, Kaohsiung 813, Taipei, Taiwan, ROC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C L","family":"Sy","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan and National Yang-Ming University, 386 Ta-Chung 1st Road, Kaohsiung 813, Taipei, Taiwan, ROC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S S J","family":"Lee","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan and National Yang-Ming University, 386 Ta-Chung 1st Road, Kaohsiung 813, Taipei, Taiwan, ROC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S R","family":"Wann","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan and National Yang-Ming University, 386 Ta-Chung 1st Road, Kaohsiung 813, Taipei, Taiwan, ROC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y S","family":"Chen","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan and National Yang-Ming University, 386 Ta-Chung 1st Road, Kaohsiung 813, Taipei, Taiwan, ROC"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,10,1]]},"reference":[{"key":"bibr-IJSA-12-124C1","first-page":"1","volume":"59","author":"Workowski KA","year":"2010","journal-title":"MMWR Recomm Rep"},{"key":"bibr-IJSA-12-124C2","first-page":"476e","volume":"30","author":"Tsai HC","year":"2010","journal-title":"Pharmacotherapy"},{"key":"bibr-IJSA-12-124C3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1979.03290490044025"},{"key":"bibr-IJSA-12-124C4","first-page":"1","volume":"96","author":"Perdrup A","year":"1981","journal-title":"Acta Derm Venereol"},{"key":"bibr-IJSA-12-124C5","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2004.012914"},{"key":"bibr-IJSA-12-124C6","doi-asserted-by":"publisher","DOI":"10.1097\/01.olq.0000187262.56820.c0"},{"key":"bibr-IJSA-12-124C7","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e31802ea4c6"},{"key":"bibr-IJSA-12-124C8","doi-asserted-by":"publisher","DOI":"10.1086\/515245"},{"key":"bibr-IJSA-12-124C9","doi-asserted-by":"publisher","DOI":"10.1086\/381227"},{"key":"bibr-IJSA-12-124C10","doi-asserted-by":"publisher","DOI":"10.1097\/01.olq.0000230481.28936.e5"},{"key":"bibr-IJSA-12-124C11","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1937.01470210013002"},{"key":"bibr-IJSA-12-124C12","first-page":"1051","volume":"116","author":"Shi X","year":"2003","journal-title":"Chin Med J"},{"key":"bibr-IJSA-12-124C13","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.4.957"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/ijsa.2012.012124","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/ijsa.2012.012124","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/ijsa.2012.012124","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T12:28:09Z","timestamp":1738067289000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/ijsa.2012.012124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":13,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1258\/ijsa.2012.012124"],"URL":"https:\/\/doi.org\/10.1258\/ijsa.2012.012124","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"type":"print","value":"0956-4624"},{"type":"electronic","value":"1758-1052"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}