{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:17:19Z","timestamp":1765887439312,"version":"3.33.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Screen"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p> To explore whether the 17% increase in cervical cancer in England in 2009 was due to the change in cervical screening policy. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> Trends in incidence of cervical cancer and of cervical intraepithelial neoplasia grade 3 (CIN3) were analysed for England, Wales and Scotland. Invasive cervical cancer data on 4079 cancers in women aged 20\u201339 diagnosed between April 2007 and August 2011 in England were analysed by single year of age. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> In England there was a 38% (95% confidence intervals [CI] 18\u201362%) increase in cervical cancer incidence rates in women aged 25\u201329 in 2009 relative to 2008, and a 30% (11\u201351%) increase in women aged 35\u201339. Compared rates in 2010 are similar to those in 2008. The average increase between 2000 and 2010 in women aged 25\u201329 was no greater in England than in Scotland and Wales (relative risk 0.98, 95% CI 0.69\u20131.39). In England there has been a gradual increase in CIN3 (particularly for ages 25\u201329) since 2003, with a more dramatic increase in 2009, but a fall in 2010. Audit data showed an increase in cancers diagnosed at age 25 in 2009\/2010 and 2010\/2011 ( P \u2264 0.0004). No increase was observed at age 26. For ages 27\u201329 an increase in cancer was observed for 2008\/2009\u20132009\/2010 when compared with 2007\/2008\u20132010\/2011 ( P &lt; 0.00001), but linear trends were not significant. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> The increase in cervical cancer in England in 2009 cannot be attributed to the lack of screening of women aged 20\u201324, or to a general decrease in the coverage or quality of cervical screening. <\/jats:p><\/jats:sec>","DOI":"10.1258\/jms.2012.012081","type":"journal-article","created":{"date-parts":[[2012,10,23]],"date-time":"2012-10-23T12:45:43Z","timestamp":1350996343000},"page":"127-132","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Dramatic increase in cervical cancer registrations in young women in 2009 in England unlikely to be due to the new policy not to screen women aged 20\u201324"],"prefix":"10.1177","volume":"19","author":[{"given":"Peter","family":"Sasieni","sequence":"first","affiliation":[{"name":"Professor of Biostatistics & Cancer Epidemiology, Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, EC1M 6BQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Castanon","sequence":"additional","affiliation":[{"name":"Epidemiologist, Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, EC1M 6BQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,10,23]]},"reference":[{"key":"bibr-JMS-12-081C1","unstructured":"Cancer Research UK. CANCERSTATS: Cervical cancer \u2013 UK incidence statistics, 2010. Available from: http:\/\/info.cancerresearchuk.org\/cancerstats\/types\/cervix\/incidence\/. (cited 2011 November)"},{"key":"bibr-JMS-12-081C2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.196"},{"key":"bibr-JMS-12-081C3","unstructured":"Office for National Statistics. Cancer statistics registrations. Registrations of cancer diagnosed in 2009, England. Series MB1 no. 40, London, 2011"},{"key":"bibr-JMS-12-081C4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600974"},{"key":"bibr-JMS-12-081C5","doi-asserted-by":"publisher","DOI":"10.1783\/147118908783332104"},{"key":"bibr-JMS-12-081C6","unstructured":"Office for National Statistics. Cancer statistics registrations, England (Series MB1). Series MB1. London, 1990\u20132009"},{"key":"bibr-JMS-12-081C7","unstructured":"Information Services Division. NHS National Services. Cancer of the Female Genital Organ. Scotland: Cancer of the cervix uteri, trends in incidence 1985\u20132009. Annual incidence 1985\u20132009. Scotland, 2011"},{"key":"bibr-JMS-12-081C8","unstructured":"The Welsh Cancer Intelligence and Surveillance Unit. Cancer Incidence in Wales, 1990\u20132009"},{"key":"bibr-JMS-12-081C9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2968"},{"key":"bibr-JMS-12-081C10","unstructured":"SasieniP, CastanonA, LouieK. NHSCSP Audit of Invasive Cervical Cancer. National Report 2007\u20132010, 2011"},{"key":"bibr-JMS-12-081C11","unstructured":"Office of Population Censuses and Surveys. Cancer statistics registrations. Cases of diagnosed cancer registered in England and Wales, 1972\u201373. Series MB1 no. 2, 1979"},{"key":"bibr-JMS-12-081C12","unstructured":"The Information Centre. Cervical Screening Programme 2005\/06. Published December 20, 2006. Available from: http:\/\/www.ic.nhs.uk\/statistics-and-data-collections\/screening\/cervical-screening\/cervical-screening-programme-2005-06"},{"key":"bibr-JMS-12-081C13","unstructured":"Health Protection Agency. STI Annual Data Tables, 2011"},{"key":"bibr-JMS-12-081C14","unstructured":"PHLS Communicable Disease Surveillance Centre. CDR Weekly, 2001"},{"key":"bibr-JMS-12-081C15","unstructured":"PHLS Communicable Disease Surveillance Centre. CDR Weekly, 2004"},{"key":"bibr-JMS-12-081C16","unstructured":"Cancer Research UK. CANCERSTATS: Cervical cancer \u2013 UK mortality statistics, 2010. Available from: http:\/\/info.cancerresearchuk.org\/cancerstats\/types\/cervix\/mortality\/. (cited 2011 November)"},{"key":"bibr-JMS-12-081C17","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6605528"},{"volume-title":"Cervix cancer screening","year":"2005","author":"IARC Working Group on the Evaluation of Cancer Preventative Strategies","key":"bibr-JMS-12-081C18"},{"key":"bibr-JMS-12-081C19","doi-asserted-by":"publisher","DOI":"10.1258\/jms.2012.012028"}],"container-title":["Journal of Medical Screening"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/jms.2012.012081","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/jms.2012.012081","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/jms.2012.012081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T02:11:30Z","timestamp":1738030290000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/jms.2012.012081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["10.1258\/jms.2012.012081"],"URL":"https:\/\/doi.org\/10.1258\/jms.2012.012081","relation":{},"ISSN":["0969-1413","1475-5793"],"issn-type":[{"type":"print","value":"0969-1413"},{"type":"electronic","value":"1475-5793"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}