{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:21:31Z","timestamp":1790623291663,"version":"4.1.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J R Soc Med"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p>Gout has not been described previously as a complication in cystic fibrosis (CF). Here we present data on nine CF patients who have presented with symptoms of acute gout. This gives an estimated prevalence of gout of around 2.5%in our adult CF population, compared to a previously described prevalence in the non-CF population of just over 1%. Serum urate is measured routinely at the annual review in our unit. Mean (SD) serum urate was 0.40(0.09)mmol\/L in male CF patients (n=108) and 0.31 (0.08)mmol\/L in female patients (n = 74). This was significantly greater than in historical controls. Thirty-seven percent of male CF patients and 36% of female patients had serum urate levels above the upper limit of normal.<\/jats:p>","DOI":"10.1258\/jrsm.2011.s11106","type":"journal-article","created":{"date-parts":[[2011,6,30]],"date-time":"2011-06-30T19:31:10Z","timestamp":1309462270000},"page":"36-39","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Gout and hyperuricaemia in adults with cystic fibrosis"],"prefix":"10.1258","volume":"104","author":[{"given":"Alex","family":"Horsley","sequence":"first","affiliation":[{"name":"Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Helm","sequence":"additional","affiliation":[{"name":"Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Brennan","sequence":"additional","affiliation":[{"name":"Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rowland","family":"Bright-Thomas","sequence":"additional","affiliation":[{"name":"Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Webb","sequence":"additional","affiliation":[{"name":"Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester, UK"},{"name":"Respiratory Research Group, Faculty of Medical and Human Sciences, The University of Manchester, Manchester Academic Health Science Centre, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Jones","sequence":"additional","affiliation":[{"name":"Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester, UK"},{"name":"Respiratory Research Group, Faculty of Medical and Human Sciences, The University of Manchester, Manchester Academic Health Science Centre, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,7,1]]},"reference":[{"key":"bibr1-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7553.1315"},{"key":"bibr2-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.024091"},{"key":"bibr3-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1987.tb01232.x"},{"key":"bibr4-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1136\/ard.47.3.218"},{"key":"bibr5-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(86)90018-1"},{"key":"bibr6-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(67)90004-6"},{"key":"bibr7-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1136\/ard.56.1.22"},{"key":"bibr8-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1002\/art.23245"},{"key":"bibr9-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035700"},{"key":"bibr10-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197607292950503"},{"key":"bibr11-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80657-4"},{"key":"bibr12-JRSM.2011.s11106","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)81225-6"}],"container-title":["Journal of the Royal Society of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/JRSM.2011.S11106","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/JRSM.2011.S11106","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/JRSM.2011.S11106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:08:36Z","timestamp":1777525716000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/JRSM.2011.S11106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":12,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1258\/JRSM.2011.S11106"],"URL":"https:\/\/doi.org\/10.1258\/jrsm.2011.s11106","relation":{},"ISSN":["0141-0768","1758-1095"],"issn-type":[{"value":"0141-0768","type":"print"},{"value":"1758-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}