{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T05:16:23Z","timestamp":1740978983959,"version":"3.38.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lab Anim"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:p> Although radioactive iodide uptake (RAIU) is one of the reliable diagnostic methods for thyroid function in adult humans, especially in the diagnosis of thyrotoxicosis, there are limited data for RAIU during pregnancy and lactation in humans and animals. Therefore, we proposed to validate RAIU for the lactating rhesus monkey to further human model studies in thyroid disease. RAIU was performed at 6 and 24 h using 100 \u00b5Ci of <jats:sup>123<\/jats:sup>I orally in four lactating monkeys. The thyroid and thigh were counted using a scintillation probe and multichannel analyser. A dose\/standard ratio of counts\/minute was calculated to compensate for background, utilizing differences in the activity between the dose administered and a standard. Thyroidal RAIU varied significantly among monkeys: 6.71 \u00b1 2.40% for the 6 h uptake and 15.44 \u00b1 7.71% for the 24 h uptake. These data showed that the RAIU test may allow a rational clinical approach to thyroid function testing for lactating rhesus monkeys. Additional studies are needed for assessing thyroid function in rhesus monkeys of varying ages and gender with clinical abnormalities. <\/jats:p>","DOI":"10.1258\/la.2009.009014","type":"journal-article","created":{"date-parts":[[2009,12,4]],"date-time":"2009-12-04T01:59:06Z","timestamp":1259891946000},"page":"155-158","source":"Crossref","is-referenced-by-count":3,"title":["Thyroidal radioactive iodide uptake in the lactating rhesus monkey"],"prefix":"10.1177","volume":"44","author":[{"given":"Aysel","family":"Ozpinar","sequence":"first","affiliation":[{"name":"Department of Biochemistry, School of Medicine, University of Acibadem, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Bruss","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Shelton","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nuclear Medicine, School of Medicine, University of California, Davis, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry","family":"Gillespie","sequence":"additional","affiliation":[{"name":"Western Institute for Food Safety and Security, School of Veterinary Medicine, University of California, Davis, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,4,1]]},"reference":[{"key":"bibr-LA-09-014C1","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199602000-00004"},{"key":"bibr-LA-09-014C2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-6480(68)90025-7"},{"key":"bibr-LA-09-014C3","doi-asserted-by":"publisher","DOI":"10.1210\/endo-104-1-175"},{"key":"bibr-LA-09-014C4","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.52.61"},{"key":"bibr-LA-09-014C5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198103193041205"},{"key":"bibr-LA-09-014C6","first-page":"284","volume":"67","author":"Fisher DA","year":"1971","journal-title":"J Ark Med Soc"},{"key":"bibr-LA-09-014C7","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-006-1442-y"},{"key":"bibr-LA-09-014C8","first-page":"561","volume":"20","author":"Bustad LK","year":"1970","journal-title":"Lab Anim Care"},{"key":"bibr-LA-09-014C9","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2000.10.779"},{"key":"bibr-LA-09-014C10","volume-title":"Principles and Practice of Nuclear Medicine","author":"Early PJ","year":"1995","edition":"2"},{"key":"bibr-LA-09-014C11","first-page":"321","volume":"67","author":"Kyzar JR","year":"1972","journal-title":"Vet Med Small Anim Clin"},{"key":"bibr-LA-09-014C12","first-page":"629","volume":"35","author":"Olson LC","year":"1985","journal-title":"Lab Anim Sci"},{"key":"bibr-LA-09-014C13","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(86)90194-8"},{"key":"bibr-LA-09-014C14","doi-asserted-by":"publisher","DOI":"10.1089\/10507250050137734"},{"key":"bibr-LA-09-014C15","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.02110927"},{"key":"bibr-LA-09-014C16","first-page":"1135","volume":"74","author":"Braverman LE","year":"1992","journal-title":"J Clin Endocrinol Metab"},{"volume-title":"Nuclear Medicine Physics","year":"1998","author":"Chandra R","key":"bibr-LA-09-014C17"},{"key":"bibr-LA-09-014C18","first-page":"28","volume":"2","author":"Leuthard M","year":"1968","journal-title":"Can J Med Technol"},{"key":"bibr-LA-09-014C19","first-page":"569","volume":"18","author":"Mantel J","year":"1970","journal-title":"Health Phys"},{"key":"bibr-LA-09-014C20","doi-asserted-by":"publisher","DOI":"10.1148\/113.2.455"},{"key":"bibr-LA-09-014C21","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.43.61"},{"key":"bibr-LA-09-014C22","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1995.00430060083010"},{"key":"bibr-LA-09-014C23","unstructured":"National Council on Radiation Protection and Measurements. 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