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Adequate monitoring alerted us to the deterioration in oxygenation, haemodynamics and cerebral oxygen metabolism. This forced us to change the level of assistance provided by the pump, and thus dramatically correct this impairment. Necropsy revealed an ostium secundum ASD. In conclusion, if hypoxaemia presents after implementation of an LVAD, the presence of a right\u2013left shunt must be ruled out. The first step must be a judicious reduction in assist device flow to minimize intracardiac shunting. Subsequently, atrial septal closure of the defect should be considered. We report an experimental model of severe hypoxaemia after placement of an LVAD as part of a larger research project. <\/jats:p>","DOI":"10.1258\/la.2011.011067","type":"journal-article","created":{"date-parts":[[2011,11,10]],"date-time":"2011-11-10T06:55:37Z","timestamp":1320908137000},"page":"77-80","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Severe hypoxaemia with a left ventricular assist device in a minipig model with an undiagnosed congenital cardiac disease"],"prefix":"10.1177","volume":"46","author":[{"given":"B","family":"Quintana-Villamandos","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Reanimation and Intensive Care, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, C\/Doctor Esquerdo, 46, Madrid 28007, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G 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