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Excess body weight increases the risk of medical conditions including type 2 diabetes, hypertension, osteoarthritis, certain cancers and is associated with increased mortality. This review examines pharmacological approaches to promote weight loss. Pharmacological therapy should be considered as an adjunct to diet and lifestyle changes. The licensed drugs orlistat, sibutramine and rimonabant are discussed. Obesity increases the risk of type 2 diabetes. Thus, the effects of metformin and exenatide are examined.<\/jats:p>","DOI":"10.1258\/mi.2008.008005","type":"journal-article","created":{"date-parts":[[2008,5,30]],"date-time":"2008-05-30T16:50:28Z","timestamp":1212166228000},"page":"57-62","source":"Crossref","is-referenced-by-count":14,"title":["Pharmacotherapy for obesity in menopausal women"],"prefix":"10.1080","volume":"14","author":[{"given":"Ashish","family":"Samat","sequence":"first","affiliation":[{"name":"Department of Diabetes and Endocrinology, Birmingham Heartlands Hospital, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asad","family":"Rahim","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Endocrinology, Birmingham Heartlands Hospital, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Barnett","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Endocrinology, Birmingham Heartlands Hospital, 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