{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T19:36:13Z","timestamp":1766518573361,"version":"3.48.0"},"reference-count":39,"publisher":"Informa UK Limited","issue":"3","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Menopause International"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p>Vitamin D, a hormone critical to the body's maintenance of serum calcium and phosphorus concentrations, is currently the subject of much scientific interest. Low levels of vitamin D have been observed in many populations and epidemiological studies have suggested a link between this biochemical state and a range of diseases, such as cancer, diabetes and multiple sclerosis. While the consequence of vitamin D deficiency is well documented for bone (rickets and osteomalacia), with mixed findings relating to falls and fractures, a causal link between vitamin D deficiency and these wider health outcomes has not been established. If these relationships were found to be causal, the morbidity and mortality resulting from low levels of vitamin D could be substantial; the current evidence base, however, most robustly supports the assessment of serum 25(OH)-vitamin D in the context of specific symptoms, low bone mineral density or biochemical abnormalities, rather than as an entity to treat in its own right or as the basis for a population-wide screening programme.<\/jats:p>","DOI":"10.1258\/mi.2011.011025","type":"journal-article","created":{"date-parts":[[2011,9,8]],"date-time":"2011-09-08T06:41:00Z","timestamp":1315464060000},"page":"102-107","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Vitamin D and the postmenopausal population"],"prefix":"10.1080","volume":"17","author":[{"given":"Christopher R","family":"Holroyd","sequence":"first","affiliation":[{"name":"MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyrus","family":"Cooper","sequence":"additional","affiliation":[{"name":"MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas C","family":"Harvey","sequence":"additional","affiliation":[{"name":"MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2011,9,8]]},"reference":[{"key":"bibr1-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.10338"},{"key":"bibr2-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-9-65"},{"key":"bibr3-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.6.1678S"},{"key":"bibr4-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1007\/BF02555135"},{"key":"bibr5-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1009570"},{"key":"bibr6-mi.2011.011025","first-page":"1009","volume-title":"Endocrinology.","volume":"2","author":"Bouillon R.","year":"2001","edition":"4"},{"key":"bibr7-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.6.1689S"},{"key":"bibr8-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2005.06.020"},{"key":"bibr9-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.07s219"},{"key":"bibr10-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-006-0084-3"},{"key":"bibr11-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2003.10719287"},{"key":"bibr12-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.090728"},{"key":"bibr13-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-1886"},{"key":"bibr14-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-010-1285-3"},{"volume-title":"IOM Report on Calcium and Vitamin D.","year":"2010","key":"bibr15-mi.2011.011025"},{"key":"bibr16-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114510002576"},{"key":"bibr17-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra070553"},{"key":"bibr18-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2364"},{"key":"bibr19-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2006.01685.x"},{"volume-title":"Effectiveness and Safety of Vitamin D in Relation to Bone Health.","year":"2007","author":"Cranney A","key":"bibr20-mi.2011.011025"},{"key":"bibr21-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/85.3.860"},{"key":"bibr22-mi.2011.011025","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2006.07.004"},{"key":"bibr23-mi.2011.011025","doi-asserted-by":"crossref","unstructured":"Lips P, van Schoor NM, Bravenboer N. In: Rosen CJ, ed. Vitamin D Related Disorders, in Primer on Metabolic Bone Diseases and Disorders of Mineral Metabolism. 7th edn. 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