{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T05:43:53Z","timestamp":1741067033736,"version":"3.38.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2012,3,9]],"date-time":"2012-03-09T00:00:00Z","timestamp":1331251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p> A primigravida was referred with hyperthyroidism in early pregnancy from longstanding Graves\u2019 disease treated with propylthiouracil. She had selective elevation of free tri-iodothyronine (fT3) levels, low normal free tetra-iodothyronine (fT4) and suppressed thyroid-stimulating hormone (TSH). Given her symptoms of thyrotoxicosis and elevated TSH receptor antibodies, therapy was tailored towards maintaining clinical and biochemical euthyroidism. However the fetus developed a goitre secondary to hypothyroidism. This case highlights the dilemmas in managing maternal T3 toxicosis while aiming for a high normal fT4 to prevent fetal hypothyroidism including the role of fetal ultrasound monitoring and amniocentesis. <\/jats:p>","DOI":"10.1258\/om.2011.110074","type":"journal-article","created":{"date-parts":[[2012,3,10]],"date-time":"2012-03-10T05:14:40Z","timestamp":1331356480000},"page":"178-180","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Neonatal hypothyroidism despite maternal tri-iodothyronine toxicosis: a management problem?"],"prefix":"10.1258","volume":"5","author":[{"given":"Vasant","family":"V Shenoy","sequence":"first","affiliation":[{"name":"Obstetric Medicine, Mater Health Services, University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janelle","family":"Nisbet","sequence":"additional","affiliation":[{"name":"Maternal and Fetal Medicine, Mater Health Services and Mater Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"G Petersen","sequence":"additional","affiliation":[{"name":"Obstetric Medicine, Mater Health Services and Mater Medical Research Institute, University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"David Mcintyre","sequence":"additional","affiliation":[{"name":"Obstetric Medicine, Mater Health Services, University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,3,9]]},"reference":[{"key":"bibr1-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-0141"},{"key":"bibr2-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.6.7573"},{"key":"bibr3-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198607033150104"},{"key":"bibr4-om.2011.110074","first-page":"1040","volume":"99","author":"Peleg D","year":"2002","journal-title":"Obstet Gynecol"},{"key":"bibr5-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6315"},{"key":"bibr6-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2555"},{"key":"bibr7-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030522"},{"key":"bibr8-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1159\/000092466"},{"key":"bibr9-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970150702"},{"key":"bibr10-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2006.19.11.1291"},{"key":"bibr11-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2011.02.002"},{"key":"bibr12-om.2011.110074","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0087"}],"container-title":["Obstetric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/om.2011.110074","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/om.2011.110074","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/om.2011.110074","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T15:06:21Z","timestamp":1741014381000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/om.2011.110074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,9]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1258\/om.2011.110074"],"URL":"https:\/\/doi.org\/10.1258\/om.2011.110074","relation":{},"ISSN":["1753-495X","1753-4968"],"issn-type":[{"type":"print","value":"1753-495X"},{"type":"electronic","value":"1753-4968"}],"subject":[],"published":{"date-parts":[[2012,3,9]]}}}